Title:
VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST
Document Type and Number:
WIPO Patent Application WO/1994/008582
Kind Code:
A1
Abstract:
A benzazepine compound represented by formulae (I) or (II) or a salt thereof, and a vasopressin antagonist or an oxytocin antagonist containing the above compound as the active ingredient.
Inventors:
OGAWA HIDENORI (JP)
KONDO KAZUMI (JP)
YAMASHITA HIROSHI (JP)
NAKAYA KENJI (JP)
KOMATSU HAJIME (JP)
TANAKA MICHINORI (JP)
KITANO KAZUYOSHI (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)
KONDO KAZUMI (JP)
YAMASHITA HIROSHI (JP)
NAKAYA KENJI (JP)
KOMATSU HAJIME (JP)
TANAKA MICHINORI (JP)
KITANO KAZUYOSHI (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)
Application Number:
PCT/JP1993/001483
Publication Date:
April 28, 1994
Filing Date:
October 15, 1993
Export Citation:
Assignee:
OTSUKA PHARMA CO LTD (JP)
OGAWA HIDENORI (JP)
KONDO KAZUMI (JP)
YAMASHITA HIROSHI (JP)
NAKAYA KENJI (JP)
KOMATSU HAJIME (JP)
TANAKA MICHINORI (JP)
KITANO KAZUYOSHI (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)
OGAWA HIDENORI (JP)
KONDO KAZUMI (JP)
YAMASHITA HIROSHI (JP)
NAKAYA KENJI (JP)
KOMATSU HAJIME (JP)
TANAKA MICHINORI (JP)
KITANO KAZUYOSHI (JP)
TOMINAGA MICHIAKI (JP)
YABUUCHI YOICHI (JP)
International Classes:
C07D223/16; C07D401/06; C07D401/12; C07D403/06; C07D403/12; C07D405/12; C07D521/00; (IPC1-7): A61K31/55; A61K31/60; C07D223/16; C07D401/00; C07D403/00; C07D405/00
Foreign References:
| JPH04154765A | 1992-05-27 | |||
| US3542760A | 1970-11-24 | |||
| US3516987A | 1970-06-23 | |||
| JPH05132466A | 1993-05-28 | |||
| JPH04321669A | 1992-11-11 |
Other References:
Regul. Pept., 45(1-2), 295-298 (1993).
J. Pharmacol. Exp. Ther., 263(2), 627-631 (1992).
Br. J. Pharmacol., 105(4), 787-791 (1992).
Lecture Summaries of Discussion on Natural Organic Compound (the 33rd) 228-235 (1991).
J. Pharmacol. Exp. Ther., 263(2), 627-631 (1992).
Br. J. Pharmacol., 105(4), 787-791 (1992).
Lecture Summaries of Discussion on Natural Organic Compound (the 33rd) 228-235 (1991).
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