VECTOR FOR PRODUCING SEROTYPE 6 RECOMBINANT ADENOVIRUS

WIPO Patent Application WO/2014/157778

A1

The present invention relates to a vector for producing a serotype 6 recombinant adenovirus and, more particularly, to: a shuttle vector for producing a serotype 6 recombinant adenovirus, which includes a gene for encoding a serotype 6 adenovirus genome that does not include an E1 region and a target protein; a rescue vector for producing the serotype 6 recombinant adenovirus, which includes a serotype 6 adenovirus genome in which the E1 region is removed; and a serotype 6 recombinant adenovirus producing method for performing homologous recombination of the shuttle vector and the rescue vector.

PARK KEERANG (KR)
CHOI YOUNG-KOOK (KR)
CHO YOUNG HWA (KR)

PCT/KR2013/006602

October 02, 2014

July 24, 2013

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SCT CO LTD (KR)
CHUNGBUK HEALTH & SCIENCE UNIVERSITY (KR)

C12N15/64; C12N7/01; C12N15/34

KR100389526B1	2004-04-03
KR100250837B1	2000-04-01
KR20080052512A	2008-06-11

DATABASE GENBANK 12 January 2011 (2011-01-12), accession no. Q413315.1
ROSS, P. JOEL ET AL.: "Construction and Characterization of Adenovirus Vectors", COLD SPRING HARBOR PROTOCOLS, vol. 4, no. 5, May 2009 (2009-05-01), pages 1 - 12
CAPONE, STEFANIA ET AL.: "A novel adenovims type 6 (ad6)-based hepatitis C virus vector that overcomes preexisting anti-ad5 immunity and induces potent and broad cellular immune responses in rhesus macaques", JOURNAL OF VILOLOGY, vol. 80, no. 4, 2006, pages 1688 - 1699

LEE, Cheo Young et al. (KR)
이처영 (KR)

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