Title:
VECTORS CAPABLE OF IMMORTALIZING NON-DIVIDING CELLS AND CELLS IMMORTALIZED WITH SAID VECTORS
Document Type and Number:
WIPO Patent Application WO2001038548
Kind Code:
A3
Abstract:
Vectors capable of stably integrating a transgene in the genome of a non-dividing cell or of a slowly-dividing cell, said vector comprising or expressing at least one immortalization molecule and cells immortalized with said vectors.
Inventors:
OCCHIODORO TERESA (AU)
SALMON PATRICK (FR)
TRONO DIDIER (CH)
SALMON PATRICK (FR)
TRONO DIDIER (CH)
Application Number:
PCT/EP2000/011723
Publication Date:
October 18, 2001
Filing Date:
November 24, 2000
Export Citation:
Assignee:
UNIV GENEVE (CH)
OCCHIODORO TERESA (AU)
SALMON PATRICK (FR)
TRONO DIDIER (CH)
OCCHIODORO TERESA (AU)
SALMON PATRICK (FR)
TRONO DIDIER (CH)
International Classes:
C12N15/09; A61K35/12; A61K35/76; A61K48/00; A61P17/02; A61P21/00; A61P31/00; A61P35/00; C12N5/10; C12N5/22; C12N7/01; C12N7/02; C12N15/63; C12N15/867; C12P21/00; C12P21/08; (IPC1-7): C12N15/63; C12N5/16; C12N5/22; C12N7/01; C12N15/64; C12P21/00
Domestic Patent References:
WO1999058701A1 | 1999-11-18 | |||
WO1998012314A1 | 1998-03-26 | |||
WO1997012622A1 | 1997-04-10 | |||
WO1999015641A1 | 1999-04-01 | |||
WO1998039463A2 | 1998-09-11 | |||
WO1998000537A1 | 1998-01-08 |
Foreign References:
US5686306A | 1997-11-11 |
Other References:
MIYOSHI,H. ET AL.: "Development of a self-inactivating lentivirus vector", JOURNAL OF VIROLOGY, vol. 72, no. 10, October 1998 (1998-10-01), pages 8150 - 8157, XP000886313
PARKINSON E K ET AL: "The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation", EUROPEAN JOURNAL OF CANCER,GB,PERGAMON PRESS, OXFORD, vol. 33, no. 5, April 1997 (1997-04-01), pages 727 - 734, XP002117437, ISSN: 0959-8049
See also references of EP 1244798A2
PARKINSON E K ET AL: "The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation", EUROPEAN JOURNAL OF CANCER,GB,PERGAMON PRESS, OXFORD, vol. 33, no. 5, April 1997 (1997-04-01), pages 727 - 734, XP002117437, ISSN: 0959-8049
See also references of EP 1244798A2
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