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Title:
VEGFR-FC FUSION PROTEIN FORMULATIONS
Document Type and Number:
WIPO Patent Application WO/2019/099921
Kind Code:
A3
Abstract:
Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept.

Inventors:
WEXLER-COHEN YAEL (US)
KAUSHIK RAHUL RAJAN (US)
CALLAHAN WILLIAM J (US)
PADALA SAI CHAKRADHAR (US)
FESINMEYER ROBERT MATTHEW (US)
Application Number:
PCT/US2018/061644
Publication Date:
June 27, 2019
Filing Date:
November 16, 2018
Export Citation:
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Assignee:
AMGEN INC (US)
International Classes:
A61K9/00; A61K9/08; A61K38/17; A61K47/02; A61K47/12; A61K47/14; A61K47/26
Domestic Patent References:
WO2016208989A12016-12-29
WO2017129685A12017-08-03
WO2014039682A12014-03-13
WO2017066554A12017-04-20
Foreign References:
US20130323242A12013-12-05
Attorney, Agent or Firm:
MAH, Angie (US)
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