Title:
VERSATILE CANINE INFLUENZA VIRUS VACCINE COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2016/186259
Kind Code:
A1
Abstract:
The present invention relates to a versatile canine influenza virus vaccine composition using the HA2 helical domain of a hemagglutinin protein, which is an influenza surface protein, and to a pharmaceutical composition for preventing or treating canine influenza virus infectious diseases. The polypeptide represented by SEQ ID NO: 3 and the polypeptide expressed by residues 379 to 474 of SEQ ID NO: 1 of the present invention can be mass-produced in E. coli, effectively produce neutralizing antibodies to various canine influenza virus subtypes, and boost an immune induction effect of the existing canine influenza vaccine through combined administration, and thus the polypeptides can be widely utilized as versatile vaccines for influenza virus subtypes and new influenza virus variants.
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Inventors:
JEONG DAE GWIN (KR)
SONG DAE SUB (KR)
KIM JEONG KIE (KR)
SONG DAE SUB (KR)
KIM JEONG KIE (KR)
Application Number:
PCT/KR2015/009617
Publication Date:
November 24, 2016
Filing Date:
September 14, 2015
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
A61K38/16; A61K39/12; A61K39/39; A61K48/00
Domestic Patent References:
WO2015006384A1 | 2015-01-15 |
Foreign References:
KR20130130326A | 2013-12-02 | |||
KR100850545B1 | 2008-08-05 | |||
US20120014972A1 | 2012-01-19 |
Other References:
WANG ET AL.: "Vaccination with A Synthetic Peptide from the Influenza Virus Hemagglutinin provides Protection against Distinct Viral Subtypes", PNAS, vol. 107, no. 44, 2010, pages 18979 - 18984, XP002675044
Attorney, Agent or Firm:
KIM, SOON WOONG (KR)
κΉμμ (KR)
κΉμμ (KR)
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