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Title:
VIOLOGEN-FUNCTIONALIZED PORPHYRINS FOR REDUCING BIOFOULING ON SURFACES
Document Type and Number:
WIPO Patent Application WO/2017/031173
Kind Code:
A8
Abstract:
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cell-adhesion specificity to a surface or material in need thereof, such as a surface of an indwelling medical implant, or a marine surface. The porphyrine compounds are characterized by having the following group attached to the porphyrine core through a carboxylate ester group. A is independently an optionally substituted N-heterocyclic aromatic ring; x is independently an integer from 0 to 6; R2 is independently lower aminoalkyl or lower aminoaryl.

Inventors:
CUI, Xinyan (1st Floor Gardner Steel Conference Center, 130 Thackeray AvenuePittsburgh, PA, 15260, US)
SNYDER, Noah (1st Floor Gardner Steel Conference Center, 130 Thackeray AvenuePittsburgh, PA, 15260, US)
CATT, Kasey (1st Floor Gardner Steel Conference Center, 130 Thackeray AvenuePittsburgh, PA, 15260, US)
ELES, James (1st Floor Gardner Steel Conference Center, 130 Thackeray AvenuePittsburgh, PA, 15260, US)
Application Number:
US2016/047290
Publication Date:
April 13, 2017
Filing Date:
August 17, 2016
Export Citation:
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Assignee:
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (1st Floor Gardner Steel Conference Center, 130 Thackeray AvenuePittsburgh, PA, 15260, US)
International Classes:
C07F13/00; A61L27/28; A61L29/08; A61L31/08; C07D487/22; C07F3/02; C07F15/02
Attorney, Agent or Firm:
SCOTT, Gregory, K. (Klarquist Sparkman, LLPOne World Trade Center, Suite 1600,121 Sw Salmon Stree, Portland OR, 97204, US)
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