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Title:
VITAMIN C SODIUM-CONTAINING EFFERVESCENT TABLET AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2018/077310
Kind Code:
A1
Abstract:
Disclosed is a vitamin C sodium-containing effervescent tablet, comprising the following components in parts by weight: 200-1120 parts of vitamin C sodium, 560-1300 parts of tartaric acid, 600-1500 parts of sodium bicarbonate, and 200-600 parts of sucrose. The present invention targets problems such as existing vitamin C effervescent tablets having high acidity after dissolving, irritating the mouth, throat, oesophagus and gastric mucosa, being unsuitable for long-term use, losing efficacy during storage due to the vitamin C oxidizing easily, and being susceptible to moisture absorption. The vitamin C sodium-containing effervescent tablet is a simple preparation, and has a stable mass.

Inventors:
HUANG AIQIANG (CN)
ZHONG WEN (CN)
HUANG AIYI (CN)
Application Number:
PCT/CN2017/114279
Publication Date:
May 03, 2018
Filing Date:
December 01, 2017
Export Citation:
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Assignee:
GUANGXI SANPOTEL HEALTH IND CO LTD (CN)
International Classes:
A61K9/46; A61K31/375; A61P3/02; A61P7/04; A61P9/06; A61P13/12; A61P21/04; A61P25/00; A61P31/00; A61P35/00; A61P37/02
Domestic Patent References:
WO2016056648A12016-04-14
Foreign References:
CN106420655A2017-02-22
CN106387918A2017-02-15
CN104434864A2015-03-25
Other References:
LI, YING ET AL.: "The Study of Major Content in Vitamin C Effervescence Tablet on Moisture Absorption", JOURNAL OF WUHAN INSTITUTE OF TECHNOLOGY, vol. 31, no. 5, 31 May 2009 (2009-05-31), pages 14 - 17
LOU, GUIQIN ET AL.: "Vitamin C Effersce: Prescription and Craft Preparation", CHINESE JOURNAL OF COAL INDUSTRY MEDICINE, vol. 13, no. 4, 30 April 2010 (2010-04-30), pages 542 - 543
ZHANG, LIFENG ET AL.: "Preparation of Vitamin C Effervescent Tablets", JOURNAL OF SHANXI MEDICAL UNIVERSITY, vol. 35, no. 1, 29 February 2004 (2004-02-29), pages 22 - 24
ZHI, SHITAO ET AL: "Synthetic Study of Sodium Ascorbate", TECHNOLOGY WIND, no. 17, 30 September 2015 (2015-09-30), pages 125 - 126
BI, DIANZHOU ET AL: "Studies on the Stability of Sodium Ascorbate Powders", JOURNAL OF SHENYANG COLLEGE OF PHARMACY, vol. 2, no. 4, 31 December 1985 (1985-12-31), pages 264 - 268
Attorney, Agent or Firm:
CHINA TRUER IP (CN)
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