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Patent Searching and Data


Title:
VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS FOR USE IN COMBINATION THERAPY
Document Type and Number:
WIPO Patent Application WO2001098294
Kind Code:
A3
Abstract:
The present invention describes novel kits and compositions comprising compounds of the formula (I):(Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer in combination therapy in a patient. The present invention provides novel compounds useful for the treatment of rheumatoid arthritis. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety.

Inventors:
RAJOPADHYE MILIND
BARRETT JOHN A
CARPENTER ALAN P JR
CHEESMAN EDWARD H
HARRIS THOMAS D
Application Number:
US0119794W
Publication Date:
January 09, 2003
Filing Date:
June 21, 2001
Export Citation:
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Assignee:
DUPONT PHARMACEUTICALS COMPANY
International Classes:
A61K41/00; A61K45/06; A61K47/48; C07D401/14; C07D403/06; C07D403/14; C07F9/6503; C07F9/6524; C07F9/6558; C07F13/00; C07K5/02; C07K5/06; C07K9/00; A61K38/00; (IPC1-7): A61K31/415; A61K51/04
Domestic Patent References:
WO1997023480A11997-07-03
WO1999058162A21999-11-18
WO1999040947A21999-08-19
WO1999006347A11999-02-11
WO2000018439A22000-04-06
WO1998047541A11998-10-29
WO2000035488A22000-06-22
Foreign References:
EP0819430A11998-01-21
EP0095906A11983-12-07
Other References:
D.G. BATT ET AL, J. MED. CHEM., vol. 43, no. 1, 2000, pages 41 - 58, XP000915237
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