Title:
WATER SOLUBLE FLUORESCENT DYES FREE OF AGGREGATION AND SERUM BINDING AND RELATED PRODUCTS AND METHODS
Document Type and Number:
WIPO Patent Application WO2000031187
Kind Code:
A9
Abstract:
The present invention thus relates to marker components, fluorescent probes, oligonucleotides, hybridization assays, and immunoassays using such products and methods for making such products. According to the present invention, detectably labeled marker components are provided that comprise a fluorophore moiety coupled to two or more small solubilizing axial ligands, [define] which preferably reduce or remove the problems of solvent sensitivity and non-specific binding.
Inventors:
DANDLIKER WALTER B (US)
HSU MAO LIN (US)
HSU MAO LIN (US)
Application Number:
PCT/US1999/026983
Publication Date:
November 30, 2000
Filing Date:
November 12, 1999
Export Citation:
Assignee:
HYPERION INC (US)
DANDLIKER WALTER B (US)
HSU MAO LIN (US)
DANDLIKER WALTER B (US)
HSU MAO LIN (US)
International Classes:
G01N21/64; C07D487/22; C09B47/00; C09B47/06; C09B47/08; G01N33/533; G01N33/543; G01N33/566; G01N33/58; (IPC1-7): C09B47/04; G01N33/533; G01N33/58
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