Title:
WATER-SOLUBLE PENTACYCLIC TRITERPENE COMPOSITION AND PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/1992/009553
Kind Code:
A1
Abstract:
A water-soluble pentacyclic triterpene composition comprising a clathrate formed between a pentacyclic triterpene compound of the amyrin family, such as oleanolic acid, ursolic acid or hederagenin, and a cyclodextrin. The water-insoluble triterpene compounds are solubilized by clathration while retaining various pharmacological functions thereof. The composition manifests the effect of caries inhibition or the like when added to food, drink, dentifrice, gargle, chewing gum, and so forth.
Inventors:
SUZUKI HIROSHI (JP)
WATANO SIGERU (JP)
SASAZUKA TADASHI (JP)
TUTUMI TAIRA (JP)
WATANO SIGERU (JP)
SASAZUKA TADASHI (JP)
TUTUMI TAIRA (JP)
Application Number:
PCT/JP1991/001577
Publication Date:
June 11, 1992
Filing Date:
November 19, 1991
Export Citation:
Assignee:
HOKKAIDOSUGAR CO LTD (JP)
International Classes:
A23G3/00; A23G3/36; A23G4/00; A23G4/12; A61K8/00; A23L29/00; A61K8/63; A61K8/73; A61K31/19; A61P1/02; A61Q11/00; C07C51/50; C07C62/32; (IPC1-7): A23L1/03; A61K7/16; C07C51/50; C07C62/32
Foreign References:
| JPS5031021A | 1975-03-27 | |||
| JPS5315467A | 1978-02-13 | |||
| JPS6136213A | 1986-02-20 | |||
| JPH01290619A | 1989-11-22 |
Other References:
See also references of EP 0555484A4
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