Title:
WIDE DYNAMIC RANGE IMAGING
Document Type and Number:
WIPO Patent Application WO/2011/143508
Kind Code:
A3
Abstract:
Systems and methods for extending the dynamic range of imaging systems, and more particularly fluorescence or luminescence imaging systems, having low optical background, and a linear detector response. Images of a sample at each of a set of exposure times are acquired, a system-level dark estimate for each exposure time is subtracted from each image to form dark-corrected images, and the different exposures (dark-corrected images) are merged into a wider dynamic-range image. Typically merging is performed on a pixel-by pixel basis.
Inventors:
LESIAK CHRISTOPHER J (US)
BOUZID AHMED (US)
FRANZEN DAVID (US)
BOUZID AHMED (US)
FRANZEN DAVID (US)
Application Number:
PCT/US2011/036357
Publication Date:
March 08, 2012
Filing Date:
May 12, 2011
Export Citation:
Assignee:
LI COR INC (US)
LESIAK CHRISTOPHER J (US)
BOUZID AHMED (US)
FRANZEN DAVID (US)
LESIAK CHRISTOPHER J (US)
BOUZID AHMED (US)
FRANZEN DAVID (US)
International Classes:
G01B11/24; G01N21/64
Domestic Patent References:
| WO2003003057A2 | 2003-01-09 |
Foreign References:
| JP2008203138A | 2008-09-04 | |||
| US20070025717A1 | 2007-02-01 |
Other References:
See also references of EP 2569615A4
Attorney, Agent or Firm:
GRAY, Gerald T. et al. (Two Embarcadero Center Eighth Floo, San Francisco California, US)
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