Title:
YEAST CELLS WITH REDUCED PROPENSITY TO DEGRADE ACRYLIC ACID
Document Type and Number:
WIPO Patent Application WO/2023/049789
Kind Code:
A3
Abstract:
The current disclosure relates to yeast cells that are genetically modified to reduce their propensity to degrade certain platform chemicals, such as acrylic acid, and to methods of preparing and using such yeast cells for the production of acrylic acid and other compounds.
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Inventors:
ZHOU JIADONG (US)
Application Number:
PCT/US2022/076840
Publication Date:
May 04, 2023
Filing Date:
September 22, 2022
Export Citation:
Assignee:
NITTO DENKO CORP (JP)
International Classes:
C12N9/16; C07K14/395; C12N1/18; C12N1/36; C12P7/40
Domestic Patent References:
| WO2013044076A1 | 2013-03-28 | |||
| WO2009155382A1 | 2009-12-23 | |||
| WO2016138303A1 | 2016-09-01 | |||
| WO2013059362A1 | 2013-04-25 | |||
| WO2005052182A2 | 2005-06-09 |
Foreign References:
| CN108004274A | 2018-05-08 |
Other References:
STINE A. ET AL: "Exploring De Novo metabolic pathways from pyruvate to propionic acid", BIOTECHNOLOGY PROGRESS, vol. 32, no. 2, 1 March 2016 (2016-03-01), pages 303 - 311, XP093025013, ISSN: 8756-7938, Retrieved from the Internet DOI: 10.1002/btpr.2233
LUNELLI B. H. ET AL: "A new process for acrylic acid synthesis by fermentative process", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 137-140, no. 1-12, 1 April 2007 (2007-04-01), pages 487 - 499, XP002591666, ISSN: 0273-2289, DOI: 10.1007/S12010-007-9074-Y
STRAATHOF A. J. J. ET AL: "Feasibility of acrylic acid production by fermentation", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 67, no. 6, 1 June 2005 (2005-06-01), pages 727 - 734, XP019331875, ISSN: 1432-0614, DOI: 10.1007/S00253-005-1942-1
CHAO GAO ET AL: "Biotechnological routes based on lactic acid production from biomass", BIOTECHNOLOGY ADVANCES, ELSEVIER PUBLISHING, BARKING, GB, vol. 29, no. 6, 26 July 2011 (2011-07-26), pages 930 - 939, XP028306427, ISSN: 0734-9750, [retrieved on 20110806], DOI: 10.1016/J.BIOTECHADV.2011.07.022
BORODINA I. ET AL: "Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via beta-alanine", METABOLIC ENGINEERING, vol. 27, 23 October 2014 (2014-10-23), AMSTERDAM, NL, pages 57 - 64, XP055270794, ISSN: 1096-7176, DOI: 10.1016/j.ymben.2014.10.003
ZHANG ZHENGBO ET AL.: "Nitrile- and amide-hydrolysing activity of acrylic acid-tolerant yeast Trichosporon asahii ZZB-1", ANN. MICROBIOL., vol. 62, no. 2, 8 July 2011 (2011-07-08), IT, pages 615 - 622, XP093015857, ISSN: 1590-4261, Retrieved from the Internet DOI: 10.1007/s13213-011-0298-2
XU XIN ET AL: "Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance", BIOTECHNOLOGY FOR BIOFUELS, vol. 12, 97, 23 April 2019 (2019-04-23), pages 1 - 14, XP093015967, Retrieved from the Internet DOI: 10.1186/s13068-019-1427-6
LUNELLI B. H. ET AL: "A new process for acrylic acid synthesis by fermentative process", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 137-140, no. 1-12, 1 April 2007 (2007-04-01), pages 487 - 499, XP002591666, ISSN: 0273-2289, DOI: 10.1007/S12010-007-9074-Y
STRAATHOF A. J. J. ET AL: "Feasibility of acrylic acid production by fermentation", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 67, no. 6, 1 June 2005 (2005-06-01), pages 727 - 734, XP019331875, ISSN: 1432-0614, DOI: 10.1007/S00253-005-1942-1
CHAO GAO ET AL: "Biotechnological routes based on lactic acid production from biomass", BIOTECHNOLOGY ADVANCES, ELSEVIER PUBLISHING, BARKING, GB, vol. 29, no. 6, 26 July 2011 (2011-07-26), pages 930 - 939, XP028306427, ISSN: 0734-9750, [retrieved on 20110806], DOI: 10.1016/J.BIOTECHADV.2011.07.022
BORODINA I. ET AL: "Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via beta-alanine", METABOLIC ENGINEERING, vol. 27, 23 October 2014 (2014-10-23), AMSTERDAM, NL, pages 57 - 64, XP055270794, ISSN: 1096-7176, DOI: 10.1016/j.ymben.2014.10.003
ZHANG ZHENGBO ET AL.: "Nitrile- and amide-hydrolysing activity of acrylic acid-tolerant yeast Trichosporon asahii ZZB-1", ANN. MICROBIOL., vol. 62, no. 2, 8 July 2011 (2011-07-08), IT, pages 615 - 622, XP093015857, ISSN: 1590-4261, Retrieved from the Internet
XU XIN ET AL: "Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance", BIOTECHNOLOGY FOR BIOFUELS, vol. 12, 97, 23 April 2019 (2019-04-23), pages 1 - 14, XP093015967, Retrieved from the Internet
Attorney, Agent or Firm:
JOHNSON, Brent A. et al. (US)
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