ZINC ION FLUORESCENT PROBE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

WIPO Patent Application WO/2020/228640

A1

The present invention relates to the field of organic light-emitting materials, and in particular, to a zinc ion fluorescent probe compound, a preparation method therefor and use thereof in zinc ion detection. The fluorescent probe compound of the present invention is named 2-(7-(2,8-dimethylquinolin-6-yl)-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)phenol, which is synthesized by using 2,8-dimethyltetrahydroquinoline and 2-(2-phenol)-1,8-naphthyridine as main raw materials. The present invention has simple synthesis steps, safe method operation, non-toxic raw materials, and low costs. The fluorescence performance test shows that the fluorescent probe compound of the present invention has high selectivity and sensitivity to Zn2+ and good chemical stability, is particularly suitable for detecting Zn2+ in an aqueous environmental system, and has excitation and emission spectra both in the visible light region, and thus can be used as a fluorescent probe in the zinc ion detection field.

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CHEN XIUWEN (CN)
GUO ZIYIN (CN)
ZHANG ZIPING (CN)
CHEN XUYAN (CN)
ZHU ZHONGZHI (CN)
YANG ZHIHAI (CN)

PCT/CN2020/089423

November 19, 2020

May 09, 2020

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UNIV WUYI (CN)

C07D471/04; C09K11/06; G01N21/64

CN110117282A	2019-08-13
CN109293651A	2019-02-01
CN107628997A	2018-01-26
CN107523292A	2017-12-29
US20050250214A1	2005-11-10
CN105038769A	2015-11-11
JP2005325074A	2005-11-24

JIAQUAN IP LAW FIRM (CN)

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