Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
alpha -HYDROXYARYLBUTANAMINE INHIBITORS OF ASPARTYL PROTEASE
Document Type and Number:
WIPO Patent Application WO2003034989
Kind Code:
A3
Abstract:
Acylated alpha -hydroxyarylbutanamines and related sulfonamides, ureas and carbamates that inhibit aspartyl protease are disclosed, as are methods of treating diseases, particularly HIV, using these compounds. The compounds have the formula (I). A representative example is formula (II).

Inventors:
OR YAT SUN
WANG GUOQIANG
ROUGAS JOHN
MATHEWS JUDE ELIZABETH
MULDOON KATE RYAN
BOYD VINCENT ALFRED
ECKSTEIN JENS WERNER
RIESINGER STEVEN WAYNE
Application Number:
PCT/US2002/033324
Publication Date:
December 04, 2003
Filing Date:
October 18, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ENANTA PHARM INC (US)
International Classes:
C07C235/42; C07C235/52; C07C235/74; C07C235/76; C07C235/84; C07C237/12; C07C237/36; C07C271/22; C07C275/24; C07C275/28; C07C275/30; C07C311/06; C07C311/19; C07C311/51; C07C323/60; C07C333/04; C07D213/65; C07D213/71; C07D215/36; C07D233/76; C07D261/08; C07D271/12; C07D279/30; C07D295/192; C07D295/215; C07D307/20; C07D311/24; C07D333/34; (IPC1-7): C07D233/76; A61K31/166
Other References:
FITCH ET AL.: "The aluminium amalgam reduction of 2-nitroalkanols promoted by ultrasound", TETRAHEDRON LETTERS, vol. 35, no. 33, 1994, pages 6013 - 6016, XP002971510
Download PDF: