Title:
'alpha','beta'-UNSATURATED KETONE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1996/036608
Kind Code:
A1
Abstract:
'alpha','beta'-Unsaturated ketone derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, both being useful as a drug, wherein the ring moiety A represents (a), (b), (c) or (d) (wherein B represents an optionally substituted aromatic ring; R2 represents hydrogen, halogeno, optionally halogenated lower alkyl, etc.; and R3 represents hydrogen, optionally halogenated lower alkyl, cycloalkyl optionally having heteroatom(s), alkoxyalkyl, optionally substituted aryl, optionally substituted heteroaryl, etc.); and R1 represents a group of formula (II) (wherein R4 and R5 are the same or different and each represents hydrogen, optionally halogenated lower alkyl, etc.; and R6 represents hydrogen, optionally halogenated lower alkyl, cycloalkyl optionally having heteroatom(s), optionally substituted aryl, otpionally substituted heteroaryl, etc.).
Inventors:
TANAKA MASAYUKI (JP)
OKITA MAKOTO (JP)
MIYAMOTO MITSUAKI (JP)
KANEKO TOSHIHIKO (JP)
KAWAHARA TETSUYA (JP)
AKAMATSU KEISHI (JP)
CHIBA KENICHI (JP)
OBAISHI HIROSHI (JP)
SAKURAI HIDEKI (JP)
ABE SHINYA (JP)
KOBAYASHI SEIICHI (JP)
YAMANAKA TAKASHI (JP)
OKITA MAKOTO (JP)
MIYAMOTO MITSUAKI (JP)
KANEKO TOSHIHIKO (JP)
KAWAHARA TETSUYA (JP)
AKAMATSU KEISHI (JP)
CHIBA KENICHI (JP)
OBAISHI HIROSHI (JP)
SAKURAI HIDEKI (JP)
ABE SHINYA (JP)
KOBAYASHI SEIICHI (JP)
YAMANAKA TAKASHI (JP)
Application Number:
PCT/JP1996/001330
Publication Date:
November 21, 1996
Filing Date:
May 20, 1996
Export Citation:
Assignee:
EISAI CO LTD (JP)
TANAKA MASAYUKI (JP)
OKITA MAKOTO (JP)
MIYAMOTO MITSUAKI (JP)
KANEKO TOSHIHIKO (JP)
KAWAHARA TETSUYA (JP)
AKAMATSU KEISHI (JP)
CHIBA KENICHI (JP)
OBAISHI HIROSHI (JP)
SAKURAI HIDEKI (JP)
ABE SHINYA (JP)
KOBAYASHI SEIICHI (JP)
YAMANAKA TAKASHI (JP)
TANAKA MASAYUKI (JP)
OKITA MAKOTO (JP)
MIYAMOTO MITSUAKI (JP)
KANEKO TOSHIHIKO (JP)
KAWAHARA TETSUYA (JP)
AKAMATSU KEISHI (JP)
CHIBA KENICHI (JP)
OBAISHI HIROSHI (JP)
SAKURAI HIDEKI (JP)
ABE SHINYA (JP)
KOBAYASHI SEIICHI (JP)
YAMANAKA TAKASHI (JP)
International Classes:
C07D335/06; A61K31/35; A61K31/352; A61K31/38; A61K31/382; A61K31/435; A61K31/47; A61K31/495; A61K31/505; A61P29/00; A61P37/00; A61P43/00; C07D215/227; C07D215/26; C07D215/36; C07D215/48; C07D311/58; C07D471/04; C07D491/052; C07D495/04; C07D215/22; (IPC1-7): C07D215/22; A61K31/35; A61K31/38; A61K31/47; C07D215/26; C07D215/36; C07D311/22; C07D355/06
Foreign References:
| JPH02256665A | 1990-10-17 | |||
| US4158663A | 1979-06-19 | |||
| EP0017332B1 | 1985-07-31 |
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