iNDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS

WIPO Patent Application WO2003074529

A3

The invention relates to compounds represented by the formula FI and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R<1> and R<11> are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

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KANIA ROBERT STEVEN (US)
ROMINES WILLIAM HENRY III (US)
CRIPPS STEPHAN JAMES (US)
HE MINGYING (US)
LOU JIHONG (US)
ZHOU RU (US)

PCT/IB2003/000740

December 24, 2003

February 17, 2003

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PFIZER (US)
KANIA ROBERT STEVEN (US)
ROMINES WILLIAM HENRY III (US)
CRIPPS STEPHAN JAMES (US)
HE MINGYING (US)
LOU JIHONG (US)
ZHOU RU (US)

C07D409/14; A61K31/4045; A61K31/4365; A61P35/00; A61P43/00; C07D495/04; (IPC1-7): C07D495/04; A61K31/4365; A61P35/00

WO2001094353A1	2001-12-13
WO2003000194A2	2003-01-03

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