Title:
A method for treating infectious respiratory diseases
Document Type and Number:
WIPO Patent Application WO1992019244
Kind Code:
A3
Abstract:
A method of treating pneumonia caused by a microorganism by administering directly into the lower respiratory tract of a host an amount of an anti-inflammatory agent effective to reduce inflammation is provided. The method may further include administering to a host an amount of an anti-infectious agent with activity against the microorganism effective to reduce the concentration of the microorganism.
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Inventors:
PRINCE GREGORY A (US)
HEMMING VAL G (US)
HEMMING VAL G (US)
Application Number:
PCT/US1992/003449
Publication Date:
December 10, 1992
Filing Date:
May 01, 1992
Export Citation:
Assignee:
JACKSON H M FOUND MILITARY MED (US)
International Classes:
A61K31/19; A61K31/405; A61K31/57; A61K31/575; A61K31/58; A61K31/60; A61K38/00; A61K39/395; A61K39/40; A61K39/42; A61K45/00; A61P29/00; C07K16/24; (IPC1-7): A61K31/57; A61K31/58; A61K31/405; A61K31/19; A61K31/60; A61K39/395; A61K31/70
Foreign References:
| GB919828A | 1963-02-27 | |||
| US3189604A | 1965-06-15 | |||
| FR5583A |
Other References:
Stomatologija, vol. 50, no. 2, 1971, (Moscow, SU), V.A. NIKITIN et al.: "The treatment of inflammatory diseases of the oral mucous membrane with "Inhalipt" aerosol", pages 12-14, see abstract
Chest, vol. 94, no. 2, suppl., August 1988, G. DÖRING et al.: "Immunologic aspects of cystic fibrosis", pages 109S-115S, see pages 109S,111S
Archives of Disease in Childhood, vol. 54, no. 8, 1979, M.E.C. HORN et al.: "Role of viruses and bacteria in acute wheezy bronchitis in childhood: a study of sputum", pages 587-592, see pages 587-588,591
ORL, vol. 48, no. 4, 1986, S. Karger AG, (Basel, DE), G. CUENANT et al.: "Efficacy of endonasal neomycin-tixocortol pivalate irrigation in the treatment of chronic allergic and bactirial sinusitis", pages 226-232, see abstract; pages 226,230,232
The New England Journal of Medicine, vol. 323, no. 21, 22 November 1990, S.A. BOZZETTE et al.: "A controlled trial of early adjunctive treatment with corticosteroids for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome", pages 1451-1457, see abstract; pages 1451,1452,1455,1456
Database WPI, accession no. 80-004275 (17), Derwent Publications Ltd, (London, GB), & RO,A,65729 (INTR. ANTIBIOTICE) 15 December 1978, see title
Annales de Pédiatrie, vol. 38, no. 7, September 1991, Ph. REINERT et al.: "Evaluation de l'association pivalate de tixocortol-néomycine versus placebo (excipient) dans la rhinopharyngite aiguë de l'enfant", pages 503-508, see abstract
"Rote Liste", 1987, abstract no. 27007: "Sunasthmax dosier-aerosol", Editio Cantor, Aulendorf/Württ, DE, see no. 27007
Chest, vol. 94, no. 2, suppl., August 1988, G. DÖRING et al.: "Immunologic aspects of cystic fibrosis", pages 109S-115S, see pages 109S,111S
Archives of Disease in Childhood, vol. 54, no. 8, 1979, M.E.C. HORN et al.: "Role of viruses and bacteria in acute wheezy bronchitis in childhood: a study of sputum", pages 587-592, see pages 587-588,591
ORL, vol. 48, no. 4, 1986, S. Karger AG, (Basel, DE), G. CUENANT et al.: "Efficacy of endonasal neomycin-tixocortol pivalate irrigation in the treatment of chronic allergic and bactirial sinusitis", pages 226-232, see abstract; pages 226,230,232
The New England Journal of Medicine, vol. 323, no. 21, 22 November 1990, S.A. BOZZETTE et al.: "A controlled trial of early adjunctive treatment with corticosteroids for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome", pages 1451-1457, see abstract; pages 1451,1452,1455,1456
Database WPI, accession no. 80-004275 (17), Derwent Publications Ltd, (London, GB), & RO,A,65729 (INTR. ANTIBIOTICE) 15 December 1978, see title
Annales de Pédiatrie, vol. 38, no. 7, September 1991, Ph. REINERT et al.: "Evaluation de l'association pivalate de tixocortol-néomycine versus placebo (excipient) dans la rhinopharyngite aiguë de l'enfant", pages 503-508, see abstract
"Rote Liste", 1987, abstract no. 27007: "Sunasthmax dosier-aerosol", Editio Cantor, Aulendorf/Württ, DE, see no. 27007
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