microRNA EXPRESSION PROMOTING AGENT AND FOOD OR BEVERAGE FOR PROMOTING EXPRESSION OF microRNA

WIPO Patent Application WO/2020/184390

A1

The present invention relates to a microRNA expression promoting agent containing pterostilbene, wherein the microRNA is at least one selected from the group consisting of miR-34a, miR-16, miR-126, miR-193b, and let-7a.

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OTSUKA KURATAKA (JP)
OCHIYA TAKAHIRO (JP)

PCT/JP2020/009481

September 17, 2020

March 05, 2020

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KEWPIE CORP (JP)

A61P1/02; A61K31/09; A61P9/00; A61P9/10; A61P19/10; A61P25/00; A61P25/28; A61P35/00; A61P43/00

WO2013051459A1	2013-04-11
WO2019049612A1	2019-03-14

WAKIMOTO, R. ET AL.: "Differential Anticancer Activity of Pterostilbene Against Three Subtypes of Human Breast Cancer Cells", ANTICANCER RESEARCH, vol. 37, no. 11, 2017, pages 6153 - 6159, XP055738597, DOI: 10.21873/anticanres.12064
MCCORMACK, D. E. ET AL.: "Genomic Analysis of Pterostilbene Predicsts Its Antiproliferative Effects Against Pancreatic Cancer In Vitro and In Vivo", JOURNAL OF GASTROINTESTINAL SURGERY, vol. 16, 2012, pages 1136 - 1143, XP035057855, DOI: 10.1007/s11605-012-1869-7
HAGIWARA, K. ET AL.: "Stilbene derivatives promote Ago2-dependent tumor- suppressive microRNA activity", SCIENTIFIC REPORTS, vol. 2, no. 314, 2012, pages 1 - 9, XP055581662, DOI: :10.1038/srep00314

HASEGAWA Yoshiki et al. (JP)

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