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Matches 1 - 50 out of 5,549

Document Document Title
WO/2021/091281A1
The present invention relates to a technique for effective intranasal delivery to the brain. More specifically, the present invention is used for diagnosing, preventing or treating central nervous system encephalopathy, neurodegenerative...  
WO/2021/091862A1
Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, di...  
WO/2021/091107A1
The present invention relates to a pharmaceutical composition for enhancing radiation sensitivity containing ageloxime D as an active ingredient, and a composition for aiding anticancer treatment, wherein the ageloxime D increases the ra...  
WO/2021/084166A1
The invention relates to a gold nanoparticle comprising as active ingredients the antioxidants anti-catalase, superoxide oxidase, glutathione, in combination with adenosine triphosphate, optionally combined with a polymer; a food, cosmet...  
WO/2021/031320A9
A nano-particle based on DNA photothermal melting, a preparation method therefor, and an application thereof. The nano-particle comprises a polydopamine core, DNA double strands, and a gadolinium salt chelate. The DNA double strands are ...  
WO/2021/086312A1
Next generation therapeutics for treatment of microrganisms (especially bacterium, fungus or certain virus) and cancer and for fluorescence diagnosis are provided. Association complex(es) effective as bactericides are formed in situ by l...  
WO/2021/081642A1
The present disclosure relates to methods of ameliorating an inflamed state in a cell or tissue by subjecting an inflamed cell or tissue to a biophotonic composition, illuminating the biophotonic composition for a time sufficient for the...  
WO/2021/084361A1
The present invention relates to exfoliated black phosphorus for use in the treatment of prostate cancer with or without irradiation by photothermal or photodynamic therapy.  
WO/2021/082512A1
Provided herein is the use of biologically inert compounds that can be photoactiveted by blue light at a specific wavelength to remove or kill drug-resistant bacteria. The photoactivatable compounds include blebbistatin analogues such as...  
WO/2021/041430A4
Disclosed herein is a method for converting light energy into mechanical energy and/or oxygen storage, purification, isolation, concentration, and/or removed. The method may comprise exposing a mixture of a polycyclic aromatic compound a...  
WO/2021/076961A1
Compositions and methods of treatment for inhibiting capillary tube regression and/or lymphatic tube regression are described, as well as factors and signaling pathways that control the regression of capillary tube networks. Capillary tu...  
WO/2021/075853A1
The present invention relates to a composition for inhibiting the growth of cancer stem cells and a use thereof. When treated with the EMP3 inhibitor, cancer stem cells expressing ALDH1 decrease in self-renewal potential, invasiveness, a...  
WO/2021/076817A2
Disclosed herein are compounds, compositions, and methods for inhibiting DGAT1 and DGAT2. Also disclosed are kits comprising DGAT1 and DGAT2 inhibitors. The compounds, compositions, and methods can be used to treat a subject with cancer,...  
WO/2021/071448A1
The present invention relates to the use of disinfected bioplastic spoons, disinfected bioplastic cutlery, disinfected bioplastic knife, disinfected bioplastic rod, disinfected bioplastic rod, disinfected bioplastic rod, disinfected biop...  
WO/2021/070896A1
The present invention addresses the problem of providing a pharmaceutical preparation which invades little the human body and can selectively kill bacteria causative of halitosis. According to the present invention, either a compound r...  
WO/2021/069879A1
The invention provides a plasmonic nanoparticle assembly comprising: a core metal nanoparticle having a first median average particle size; and at least two arms, each arm comprising: at least one linking molecule and at least two outer ...  
WO/2021/070920A1
A cyclic peptide that has a cyclic structure consisting of 4-30 amino acids or derivative(s) thereof, or a pharmaceutically acceptable salt thereof. In the cyclic structure, the cyclic peptide contains at least carboranylalanine(Cba) and...  
WO/2021/071413A1
A yeast cell for use in the treatment and/or alleviation of allergy and/or symptoms caused by allergy, wherein the yeast cell has been treated with electromagnetic waves in the range of 1 GHz to 300 GHz, or said yeast cell has been grown...  
WO/2021/070039A2
Disclosed herein are methods of identifying homologous recombination deficiency (HRD) in omics data, comprising generating a mutational spectrum from omics data; and using the mutational spectrum in a trained model to identify HRD. Furth...  
WO/2021/071876A1
The invention provides novel photolytic compounds and prodrugs, nanoparticles and compositions thereof, and methods of conducting photolysis mediated by triplet-triplet annihilation.  
WO/2021/067545A2
The present disclosure relates to listeriolysin O polypeptides and vaccine compositions for treating and preventing Listeria infection.  
WO/2021/067850A2
The present disclosure relates to a method to detect or measure circRNAs in a biological sample of a subject. In particular the present disclosure is directed to a method for diagnosing a neurological, neurodegenerative, or neuropatholog...  
WO/2021/067818A2
Methods and apparatus for efficient data transmit and receive operations using polling of memory queues associated with interconnect fabric interface. In one embodiment, Non-Transparent Bridge (NTB) technology used to transact the data t...  
WO/2021/064180A1
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte differentiation compared to q-VD-OH by its ability to efficiently inhibit caspase-8, which is instrumental to this process. In addition, they ha...  
WO/2021/066081A1
Provided is a novel method with which spores, etc. can be sterilized easily and with excellent safety. This radical manufacturing method is characterized: by comprising a treatment step in which radicals are generated by irradiating a ...  
WO/2021/067577A1
Articles and methods for increasing the triplet upconversion threshold, e.g, by utilizing a heavy atom- functionalized triplet exciton upconverter, are generally described. Some embodiments, for example, are directed to articles and meth...  
WO/2021/067491A1
The present invention includes system, methods, and compositions for the generation of novel oxygen microbubbles, and in particular oxygen microbubbles with a longer acyl-chain phospholipid for increased circulation persistence and oxyge...  
WO/2021/058979A1
The invention addresses radioresistance in cancer treatment involving radiotherapy and, in particular, limitations associated with the use of the drug sulfasalazine. Specifically, it provides a series of compounds for use as radiosensiti...  
WO/2021/060498A1
The present invention provides: nanoparticles including a compound that includes porous silica and at least one high-Z atom selected from the group consisting of gadolinium atoms, iodine atoms, gold atoms, silver atoms, and platinum atom...  
WO/2021/030145A3
The present disclosure provides a system for functional ultrasound imaging, where the system comprises: a) an apparatus for delivering a nucleic acid encoding a mechanosensitive ion channel to a target neural cell population in a region ...  
WO/2021/055703A1
Described herein are tough gel compositions that comprise an interpenetrating networks (IPN) hydrogel. The IPN hydrogel comprises a first polymer network (covalently crosslinked) and a second polymer network (ionically crosslinked), at l...  
WO/2021/054490A1
The present invention relates to an amphiphilic polymer, water-dispersible metal nanoparticles comprising same, and a manufacturing method therefor, the amphiphilic polymer comprising a polyethylene glycol repeating unit in the backbone,...  
WO/2021/054767A1
The purpose of the present invention is to prepare carbon-coated gadolinium oxide as a contrast medium which is non-toxic in vivo and capable of dual-modal imaging, by coating, with carbon, the surface of gadolinium oxide. The carbon-coa...  
WO/2021/053173A1
The present disclosure relates to the field of nanomedicine, in particular for treating cancers. The present disclosure more specifically provides new methods of treating undesirable M2-polarized macrophages and/or inducing M1 macrophage...  
WO/2021/055554A2
The present invention provides methods to improve a cancer patient's response to immune checkpoint inhibitor (ICI) therapy, and functional test to predict likelihood of response. Specifically, the invention provides methods to improve pa...  
WO/2021/049519A1
The purpose of the present invention is to provide a method for preventing precipitation due to storage of an injectable solution for boron neutron capture therapy. The present invention provides a method for preventing precipitation o...  
WO/2021/047099A1
Disclosed is a method for synthesizing a novel ferrihydrite nano-photosensitizer, the method comprising the following steps: weighing 303 mg of an Fe(NO3)39H2O solid, and sufficiently dissolving same in 30 ml of distilled water to formul...  
WO/2021/050658A1
Provided are compositions, products of manufacture, kits and methods for remotely-controlled and non-invasive manipulation of intracellular nucleic acid expression, genetic processes, function and activity in live cells such as T cells i...  
WO/2021/049898A1
The present invention relates to a system for corneal cross-linking of injured corneas, treating keratoconus, or correcting vision, the system comprising: a hyaluronic acid-dye conjugate; and a contact lens including an LED light source....  
WO/2021/045485A1
The present invention relates to an immune microbubble complex, and a use thereof. An immune microbubble complex (IMC) according to the present invention is obtained by conjugating antibodies to microbubbles, wherein the microbubbles hav...  
WO/2021/046100A1
Provided are compositions, combinations, and methods and uses for treating a subject having a tumor or lesion, including those not responsive or resistant to prior therapeutic treatments, such as prior immune checkpoint inhibitor treatme...  
WO/2021/044627A1
The present invention comprises a drug administration step S1 and a light irradiation step S2 of irradiating cells C with therapeutic light L to at least 1 J/cm2, the therapeutic light L having an intensity of more than 0 mW/cm2 and 50 m...  
WO/2021/041430A1
Disclosed herein is a method for converting light energy into mechanical energy and/or oxygen storage, purification, isolation, concentration, and/or removed. The method may comprise exposing a mixture of a polycyclic aromatic compound a...  
WO/2021/040570A1
This invention relates to the field of medicine, particularly to a medicament for treating bacterial infections, which presents a technology-processed product resulting from multiple serial dilutions of the stock substances of antibodies...  
WO/2021/035349A1
This application relates to compositions comprising cellulose nanocrystals (CNCs) and photosensitizer molecules conjugated to the CNCs. In some embodiments the compositions generate reactive oxygen when exposed to light. Methods of prepa...  
WO/2021/042045A1
The present invention relates to high throughput in vitro genetic manipulation. In particular, it relates to scalable CRISPR gene insertions in mammalian cells.  
WO/2021/041942A1
The present invention relates to a methods for modulating Collagen Prolyl 4-hydroxylase (C-P4H1) in a cell. The present invention further relates to methods for inhibiting a cancer cell. The instant invention also relates to methods for ...  
WO/2021/031320A1
A nano-particle based on DNA photothermal melting, a preparation method therefor, and an application thereof. The nano-particle comprises a polydopamine core, DNA double strands, and a gadolinium salt chelate. The DNA double strands are ...  
WO/2021/031321A1
A multi-color up-conversion nanoprobe, a preparation method therefor, and an application thereof. The nanoprobe comprises up-conversion nano particles and a silicon dioxide layer sequentially from inside to outside. The up-conversion nan...  
WO/2021/027509A1
A proton-triggering-based nanodrug system having hydrophilic-hydrophobic-size double conversion characteristics, and a preparation method therefor and use thereof. The system is self-assembled by a benzene ring-containing aromatic small ...  

Matches 1 - 50 out of 5,549