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WO/2023/044389A1 |
The present disclosure describes improved polymer compositions, such as GelMA or GelAC polymer compositions. In certain embodiments, the improved polymer compositions comprise a corticosteroid active agent, such as loteprednol (i.e., lot...
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WO/2023/042875A1 |
The present invention addresses the problem of providing: a gel formation kit which can be used for the production of a non-human animal and enables the formation of a tumor with high efficiency within a short period of time in the produ...
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WO/2023/044055A1 |
The present invention provides biodegradable fibers, non-woven scaffolds comprising the same, methods of making the same, and methods of use thereof. The composition and methods disclosed herein provide, among other things, packaging mea...
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WO/2023/041798A1 |
The present invention relates to a method for producing a dermal or skin or epidermal equivalent on a two-layer substrate comprising a layer of at least 200 nm in thickness and having a porosity less than or equal to 5 μm formed by elec...
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WO/2023/044463A1 |
Materials, methods, and techniques herein relate to relate to silk protein films. More specifically, the instant disclosure relates to the functionalization and properties of silk protein films, which may be used for treatment applicatio...
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WO/2023/035720A1 |
The present application relates to a method for preparing a pegylated collagen-like protein and the use thereof, which belong to the field of biotechnology. Provided in the present application is a method for preparing a pegylated collag...
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WO/2023/035721A1 |
The present application relates to the field of biotechnology, and relates to a bionic cornea and a preparation method therefor. The present application provides a bionic cornea. A raw material of the bionic cornea is pegylated collagen....
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WO/2023/039427A1 |
Disclosed are compositions, devices, kits, and methods for treatment of Enterobacteriaceae infection. Aspects of the present disclosure are directed to bacteriophage compositions comprising one or more of ES17, ES19, HP3, HP3.1, and HP3....
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WO/2023/035046A1 |
Provided is a method of coating a substrate with a hyperbranched polyglycerol. The hyperbranched polyglycerol is formed by activating the surface of the substrate followed by polymerisation of monomers of glycidol, or derivatives thereof...
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WO/2023/037026A1 |
The invention relates to an adhesive/sol-gel hybrid coating that is an osteoinductive composite material with biocompatible characteristics as of the first 24 hours after use on implantable surfaces or as independent bone filler. In the ...
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WO/2023/037988A1 |
Provided is a method for storing or transporting renal cells, which are usable for a drug evaluation system, have high cell viability and preserve renal physiological function, at a temperature lower than the culture temperature. One asp...
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WO/2023/038463A1 |
The present invention pertains to a 6-arm PEG hydrogel composition, the physical properties of which transition over time within 30 minutes from a sol to a gel. According to the present invention, two types of PEG derivatives are include...
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WO/2023/035731A1 |
The present invention relates to a degradable iron-based alloy material, a preparation method therefor and an application thereof. Raw material components of the degradable iron-based alloy material comprise Fe-Mn-C pre-alloy powder and ...
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WO/2023/036922A1 |
A method of preparing a functional hydrogel material (9) for injection into a human or animal body is indicated, the method comprising the step of polymerizing a prepolymer solution (1), in order to form the functional hydrogel material ...
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WO/2023/038853A1 |
A customized resorbable three-dimensional scaffold for oral and maxillofacial bone grafting involves merging two sets of three-dimensional information obtained from a patient, the first set includes three-dimensional bone information and...
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WO/2023/039371A1 |
The disclosure generally relates to methods, cells, and compositions for preparing cardiac extracellular matrix. In particular, provided herein are methods tor preparing a cardiac extracellular matrix using SUSD2 High fibroblasts and SUS...
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WO/2023/037192A1 |
Composition or system of a radiopaque agent comprising at least a first radiopaque agent in the form of a powder and at least a second radiopaque agent in the form of granules, wherein the first radiopaque agent is an equal or different ...
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WO/2023/035767A1 |
A 3D multi-branch bionic stent, a preparation method therefor and an application thereof. The 3D multi-branch bionic stent comprises: a main fiber tube, one end of the main fiber tube being connected to at least two primary branch fiber ...
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WO/2023/035719A1 |
Provided is a pegylated collagen-like protein. The pegylated collagen-like protein contains a collagen-like protein, and PEG-40k and PEG-20k modified on the collagen-like protein; the modification of PEG-40k and PEG-20k can significantly...
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WO/2023/029161A1 |
A natural collagen material, a preparation method and an application of the natural collagen material, and a subdermal filler, belonging to the field of biomedical materials. The natural collagen material has a significantly increased co...
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WO/2023/034400A1 |
Embodiments disclosed herein relate scaffolds containing fluoridated apatites sintered at a temperature of at least 950 °C and with at least one integration aid to increase integration of the scaffold in a patient, as well as methods of...
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WO/2023/031289A1 |
A method of forming an electroconductive aerogel or hydrogel for use in tissue repair. The method comprises a) forming a suspension of nanoparticles of conductive polymeric material from a miniemulsion of monomeric material in an aqueous...
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WO/2023/034313A1 |
There is disclosed a tool having a set of features for forming a domed acellular dermal matrix (ADM) graft. An acellular dermal matrix (ADM) graft product includes an ADM graft derived from full-thickness skin, with a pre-formed domed sh...
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WO/2023/033137A1 |
One of the purposes of the present invention is to provide a novel method for producing a kidney organoid. Provided is a method for producing a kidney organoid, the method being characterized by including culturing an initial kidney or...
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WO/2023/033012A1 |
[Problem] To provide a polydimethylsiloxane-containing monomer exhibiting good compatibility with hydrophilic monomers, hydrophilic polymers and the like; and furthermore to provide a polymer that exhibits an anti-lipid adhesion property...
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WO/2023/034389A1 |
A tissue scaffold implant for expanding a stenotic lumen is provided that includes a bridge structure defining at least two angled sides and a lateral anchor integrally formed with the bridge structure. The lateral anchor is configured t...
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WO/2023/032948A1 |
The present invention provides a biocompatible film having biological safety and a stable effect. The present invention provides a biocompatible film containing magnesium and optionally containing calcium, in which the weight of calcium ...
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WO/2023/034614A1 |
Systems and methods for nerve repair can include a polymer configured to form an elongated conduit to receive an in vivo nerve therein and provide a mechanical stabilization to the in vivo nerve. The polymer can be configured to degrade ...
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WO/2023/032947A1 |
The present invention provides a biocompatible material in which a hydrophilic substrate is protected by a metal film, the metal film being dissolved when the biocompatible material is used in a living body environment, enabling the prot...
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WO/2023/028651A1 |
The disclosure relates to a scaffold graft material, or platelet rich plasma (PRP) graft, and method of production thereof, for tissue repair and/or support (e.g. reinforcement). In one particular application, the scaffold material is us...
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WO/2023/032945A1 |
The present invention addresses the problem of providing: a therapeutic agent for arthropathy, which comprises a synovium-derived mesenchymal stem cell that contains a molecule essential for the treatment of joints; and a method for prod...
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WO/2023/031618A1 |
The present invention relates to compositions suitable for tissue engineering. In particular, the invention relates to compositions comprising scaffolds which have been designed and produced with properties making them particularly suite...
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WO/2023/033775A1 |
The present invention provides a method for increasing the hydrophilicity of a surface of a dental implant made of conductive material. In the method, the implant is first subjected to a pre-treatment for removing oxide. The pre-treated ...
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WO/2023/032441A1 |
Developed is a method for creating cartilage tissue to solve the following problems. 1. Cartilage differentiation is not hindered by forming. 2. The cartilage can be formed into an intended shape without using a scaffold. A method for ...
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WO/2023/031972A1 |
The present invention discloses Solid State Luminogens based on pyridinum scaffolds. Particularly, the present invention discloses the design and development of novel N-doped ionic solid state emitters of general Formula (I) and to the p...
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WO/2023/030435A1 |
Provided are compositions for cartilage defects or deficiencies repair, augmentation or treatment comprising an injectable, in situ polymerizable collagen composition and chondrocytes or stem cells in the collagen composition. Also provi...
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WO/2023/034460A1 |
This application describes a device and method to locally administer drugs via in vivo implantation at a disease site. The device minimally comprises a porous and topologically closed cage, one or more biomaterial particles enclosed by t...
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WO/2023/033013A1 |
[Problem] To provide a polydimethylsiloxane-containing monomer exhibiting good compatibility with hydrophilic monomers, hydrophilic polymers and the like; and furthermore to provide a polymer that exhibits an anti-lipid adhesion property...
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WO/2023/028664A1 |
Disclosed are injectable compositions. Such compositions may be formed from cellulosic fibers and a deep eutectic solvent. Also disclosed are methods of preparing an injectable composition, which comprises: (i) contacting cellulosic fibe...
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WO/2023/032840A1 |
Provided are a tissue body formation device that enables an improvement in the ratio of a dense connective tissue, and a tissue body formation method. An exterior part 10 that separates an environment and a hollow space in a partition wa...
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WO/2023/033749A1 |
Disclosed is a method of preparing a Hyaluronic acid-Alginate (HA-Alg) hydrogel, the method comprising: dissolving a required amount of amine-hyaluronic acid (HA-NH2) in a first buffer solution to form an HA-NH2 solution of a first prede...
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WO/2023/033515A1 |
The present application relates to a bone graft material composed of porous whitlockite including nanopores with a size of 100 nm to 1,000 nm, micropores with a size of 1 μm to 100 μm, and macropores with a size of 100 μm to 1,000 μm...
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WO/2023/025944A1 |
The present invention relates to an implant having a surface comprising a coating on at least a portion of the surface of the implant, wherein the coating comprises a first layer, the first layer comprising a polylactide and silver ions....
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WO/2023/027330A1 |
The present invention relates to a hyaluronic acid (HA) filler composition using polyethylene glycol (PEG) and glycolic acid (GA) as crosslinking agents and a method for preparing same. The present invention is characterized by preparati...
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WO/2023/027472A1 |
The present invention pertains to an intervertebral body fusion cage having a shell-type porous structure. More specifically, the present invention pertains to an intervertebral body fusion cage having a shell-type porous structure, wher...
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WO/2023/028030A1 |
Diversified grafts suitable for use in repair and reconstruction procedures are provided. Some diversified grafts (10) comprise two or more heterogenous features (118a, 118b) which form regions having different preferred properties. A di...
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WO/2023/024202A1 |
A photo-cured forming composite hydrogel matrix precursor and a preparation method therefor and a stent having the precursor. The photo-cured forming composite hydrogel matrix precursor comprises methacrylated gelatin, sodium alginate, s...
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WO/2023/024724A1 |
Provided in the present invention are a photothermal-curing resin composition, and a preparation method therefor and the use thereof. The resin composition comprises a combination of specific parts of a prepolymer, a monomer, a photoinit...
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WO/2023/027508A1 |
The present invention relates to a degradable ultrasound transducer which is naturally degraded in a use environment, wherein a degradable ultrasound transducer according to an embodiment of the present invention comprises: a piezoelectr...
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WO/2023/023772A1 |
The present invention is concerned with a manufactured article prepared from a biomaterial comprising isolated and purified type I collagen fibrils derived from abalone and a method of preparing such an article. The manufactured article ...
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