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WO/2017/019494A1 |
An implantable orthopedic device having an antimicrobial coating on at least one surface thereof is disclosed. The antimicrobial coating includes alexidine and a carrier polymer.
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WO/2017/019553A1 |
An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) f...
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WO/2017/007430A1 |
Disclosed herein is a drug-coated medical device in the form of a balloon having an inner surface and an outer hydrophobic surface, an adhesion balance layer directly on the outer hydrophobic surface of the balloon, comprising a hydrophi...
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WO/2016/204217A1 |
Provided is a novel biocompatible material having improved biocompatibility. A biocompatible material comprising a fluoropolymer, said biocompatible material being characterized in that the fluoropolymer is a copolymer of a fluoroolefin ...
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WO/2016/201202A1 |
Medical devices, systems, and methods for treating conditions using antithrombin-heparin conjugates are disclosed. For example, medical devices can be coated with antithrombin-heparin (ATH) resulting in reduced thrombogenicity. Various c...
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WO/2016/196633A1 |
Techniques for modifying the surface of implantable devices, such as bioprosthetic valves, to improve the biocompatibility of the implantable devices are provided. In particular, a customizable, non-fouling surface coating may be formed ...
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WO/2016/187698A1 |
Provided herein are compositions comprising: (a) a polymeric catechol binder, such as: polymeric dopamine, polymeric norepinephrine, polymeric epinephrine; polymeric pyrogallol, polymeric tannic acid, polymeric hydroxyhydroquinone, polym...
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WO/2016/190407A1 |
The purpose of the present invention is to provide an antithrombotic material which exhibits high antithrombotic activity that is sustained over a long period, while reducing the thickness of the coating material. The present invention i...
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WO/2016/190202A1 |
Provided is a multi-ply tubular woven fabric structure that is useful as a base material of a hose for protecting a linear object such as a wire or cable for transporting a fluid or powder or a conduit tube, a tubular filter, an artifici...
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WO/2016/184872A1 |
The invention relates to a heparin-functionalized semi-permeable membrane comprising at least one layer of porous biocompatible polymer, and one layer of non-woven biocompatible polymer wherein said heparin is covalently bound to a layer...
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WO/2016/175548A1 |
The present invention relates to an anti-adhesion agent containing a natural biocompatible polymer and a DNA fragment mixture, and a preparation method therefor. The anti-adhesion agent of the present invention has an excellent effect of...
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WO/2016/168710A1 |
Compositions and methods for preventing thrombogenesis can include antithrombin and heparin. In one example, a conjugate of antithrombin and heparin where at least 50 wt% of the heparin is conjugated to antithrombin can be present. Furth...
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WO/2016/158388A1 |
The purpose of the present invention is to provide: a copolymer having blood compatibility and antithrombotic properties of greatly suppressing protein adhesion so as to be usable even when being in contact with a biological component su...
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WO/2016/159243A1 |
The present invention addresses the problem of providing an antithrombotic metallic material which has improved safety against low hemolytic toxicity and can exhibit high antithrombotic properties sustainably. The present invention provi...
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WO/2016/104596A1 |
Provided is a novel low protein adsorption material that resists protein adsorption and has excellent heat resistance, alkali resistance, and molding processability. The low protein adsorption material is characterized by comprising a fl...
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WO/2016/093230A1 |
This bodily-fluid-contacting medical tool has a coating film provided to a bodily-fluid-contacting surface thereof. The coating film includes a block polymer provided with: an acrylic polymer block formed from an acrylic monomer having a...
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WO/2016/073933A1 |
A suture anchor apparatus comprising: an anchoring member made from a metal-based material and comprising a generally elongated body having a proximal end and a distal end, wherein an outer surface of the anchoring member defines a threa...
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WO/2016/067795A1 |
[Problem] To provide: a material that is nonadhesive to biological substances, said material being capable of inhibiting or preventing adhesion of biological substances such as cells and blood components; a curing composition that is usa...
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WO/2016/061419A1 |
Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase sep...
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WO/2016/059024A1 |
A method for growing carbon nanowalls on a substrate of an implantable medical device by means of a processing chamber is provided, said method comprising: providing said substrate in said processing chamber, evacuating said processing c...
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WO/2016/044836A1 |
Microparticles containing heparin or a heparin-like polymer and a biocompatible polymer are described. The heparin or the heparin-like polymer and the biocompatible polymer can be indirectly linked together by a coupling agent, which can...
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WO/2016/037239A1 |
A plasma-activated coating (PAC) process covalently binds enzymes in their bioactive state, has low thrombogenicity and can be robustly applied to medical devices, resisting delamination when deployed in vivo. Applying this process to at...
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WO/2016/030358A1 |
According to the present invention a method which prevents excessive adsorption of microvesicles on the surfaces of tools used for sampling, storing and handling body flu- ids containing microvesicles is provided. The method comprises th...
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WO/2015/189716A1 |
Thrombosis resistant mechanical prosthetic heart valve is technical medical equipment. Thromboembolic is one of the most important complications of the available mechanical valves which may appear as a clot formation on the valve, its dy...
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WO/2015/188716A1 |
An anticoagulation coating is formed on the surface of a carrier, and the coating is formed by alternate adsorption of positively charged and negatively charged polyelectrolytes. The present invention has a simple process, can be achieve...
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WO/2015/175899A1 |
The inventive composition first is highly viscous, remaining in place when administered to a patient. Then it decreases in viscosity and liquefies, facilitating easy removal, after a period of time ranging from minutes to weeks, such as ...
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WO/2015/157533A1 |
Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating la...
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WO/2015/137259A1 |
A method for producing a medical tool which has a surface lubricant layer on a surface of a base material and the surface of which exhibits lubricity and antithrombogenicity when wet, the method including a step of forming a coating laye...
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WO/2015/128475A1 |
The present invention relates to a method of producing a solid carrier, to which at least one affinity-reagent is coupled that binds specifically to a target molecule, comprising the steps of (i) coupling at least one affinity-reagent to...
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WO/2015/125890A1 |
The present invention relates to a medical material that contains a copolymer that comprises a repeating unit (A) that is indicated by formula (1) and a repeating unit (B) that is indicated by formula (2), the repeating unit (A) being 0....
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WO/2015/098763A1 |
This medical device comprises a substrate and a coat layer that contains an antithrombogenic material covering the substrate surface. The antithrombogenic material comprises a copolymer that contains a repeating unit (A) represented by f...
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WO/2015/098764A1 |
The present invention relates to a medical material which comprises a copolymer that contains a repeating unit (A) (for example, one derived from N-vinylacetamide) and a repeating unit (B) (for example, one derived from methoxyethyl acry...
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WO/2015/087966A1 |
The purpose of the present invention is to provide an antithrombotic material and an antithrombotic article having improved antithrombotic properties and improved heat resistance, an antibacterial material and an antibacterial article ha...
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WO/2015/080176A1 |
The purpose of the present invention is to provide an anti-thrombotic material in which heparin or an anti-thrombotic compound other than a heparin derivative is fixed to a base material, elution of the compound exhibiting anti-thromboti...
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WO/2015/080177A1 |
The purpose of the present invention is to provide an antithrombotic material capable of enhancing safety in terms of low hemolytic toxicity and actualizing a high antithrombotic property persistently over an extended period of time. The...
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WO/2015/071313A1 |
The invention concerns polyurethane (PUR) having an antithrombogenic coating, wherein the antithrombogenic coating comprises at least one antithrombogenic substance covalently bound to a surface of the PUR via at least two bonds, wherein...
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WO/2015/048619A2 |
A medical device includes a base material having an immobilized enzyme and dextran sulfate. The dextran sulfate has a molecular weight that is less than 40 kilo dalton (kDa). The medical device is formed from at least a base material. An...
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WO/2015/031265A1 |
The invention includes conductive polymeric coatings, medical device, coating solutions and methods of making the same. A coating solution for forming a conductive polymer layer can include a conductive monomer, at least one photoreactiv...
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WO/2014/204402A1 |
The invention concerns a medical or veterinary device comprising a covalently immobilized and cross-linked agarose coating, a method for the production of same and a cross-linked agarose coating.
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WO/2014/178256A1 |
The present invention relates to an adhesion preventing agent which comprises an amphiphilic compound represented by general formula (I). (In the formula, X and Y each represents a hydrogen atom or together represent an oxygen atom, n re...
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WO/2014/174237A1 |
Antimicrobial and antithrombogenic polymer or polymeric blend, compounds, coatings, and materials containing the same, as well as articles made with, or coated with the same, and methods of making the same exhibiting improved antimicrobi...
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WO/2014/133102A1 |
Provided is a biocompatible polymer composition comprising a structure having at least one side chain ether group and a main chain formed from a biodegradable polymer skeleton, as well as an intermediate compound for producing the polyme...
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WO/2014/123077A1 |
Provided are a medical coating material which has excellent hydrophilic properties and a medical device which is coated with said material. This medical coating material comprises a copolymer which includes a segment A having vinylimidaz...
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WO/2014/112956A1 |
Method of treatment of a vascular graft addresses the need for improved methods of increasing hemocompatibility of vascular grafts made from polyethylene terephthalate polymers against the state of the art. The present invention does not...
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WO/2014/107690A1 |
Hemo-compatible, anti- and non-thrombogenic, heparin-based bioactive coat a surface to be contacted with blood, such as a surface of an oxygenator device (e.g., a Hollow Fiber Membrane (HFM) surface) or an artificial lung, which coatings...
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WO/2014/101748A1 |
The present invention provides a collagen material with a local hemostatic or anticoagulant function. An amino acid polar group on a collagen peptide chain, such as carboxyl or amino, reacts, and electrical property of the polar group is...
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WO/2014/092239A1 |
The present invention relates to a tissue sealant in which collagen and fibrin are mixed and to a method for preparing same. To this end, the method of the present invention comprises the steps of: mixing a first material using fibrinoge...
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WO/2014/081345A1 |
The method for manufacturing a bioresorbable hybrid vascular implant of small diameter comprises using a polymer composition produced on the basis of polyhydroxybutyrate with hydroxyvalerate (PHBV) and epsilon-polycaprolactone (PCL), ...
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WO/2014/077498A1 |
The present invention relates to a needle housing a suture thread, and can be used in various ways for purposes such as post-surgical suturing, shaping and lumbar pain treatment. To this end, the present invention comprises: a needle (10...
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WO/2014/071387A1 |
Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In ...
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