Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 4,156

Document Document Title
WO/2020/061067A9
The disclosure relates to compositions and methods of treating, improving, and accelerating the healing of large segmental bone defects in a subject. The method comprises administering to a patient in need of treatment an effective amoun...  
WO/2021/058835A1
The present disclosure relates to acidic sophorolipids and uses thereof, including for use in therapy and, in particular, in the treatment or prevention of cancer and associated pathologies.  
WO/2021/053996A1
[Problem] To provide a medical instrument that has excellent sliding properties (in particular, piercing characteristics) and is able to exert excellent antithrombogenicity. [Solution] This medical instrument comprises: a base material h...  
WO/2020/240446A1
A plasma-activated coating (PAC) process covalently binds enzymes in their bioactive state, has low thrombogenicity and can be robustly applied to medical devices, resisting delamination when deployed in vivo. Applying this process to at...  
WO/2020/236139A1
Intraocular lenses with pressure sensors embedded therein, and methods of manufacture.  
WO/2020/218058A1
A tungsten wire (10) is one made from tungsten or a tungsten alloy, wherein the wire diameter D of the tungsten wire (10) is 100 μm or less and the number of twists to torsional rupture per 50 mm of the tungsten wire (10) is 250×exp(-0...  
WO/2020/213529A1
The present disclosure provides an antithrombogenic material having a substrate and a surface modified layer provided on at least a portion of the substrate, wherein: the surface modified layer includes a block copolymer having a first s...  
WO/2020/212978A1
There is provided herein a method of coating a polyurethane surface of an insertable medical device, the method comprising obtaining an insertable medical device or a part thereof comprising a polyurethane surface; performing a direct th...  
WO/2020/214836A1
The present invention pertains to methods of coating antimicrobial peptides on the biomaterial and the biomaterial coated thereby. The coating solution described herein comprises one or more antimicrobial peptides (AMPs) dissolved in a b...  
WO/2020/190214A1
Disclosed herein is a medical device, comprising a covalently-bonded heparin coating on a substrate, where the covalently bonded heparin coating is the reaction product of (a) an isocyanate-bearing material on or covalently bonded to the...  
WO/2020/181642A1
A preparation method for an ionic bond-covalent bond synergy-based surface heparinized anticoagulant medical device. In said method, firstly, a hydrophilic polymer of which the side chain is modified by a low molecular weight hyperbranch...  
WO/2020/061067A8
The disclosure relates to compositions and methods of treating, improving, and accelerating the healing of large segmental bone defects in a subject. The method comprises administering to a patient in need of treatment an effective amoun...  
WO/2020/108670A3
Provided is a hemostatic composition comprising trypsin and zeolite, wherein pore channels of the zeolite are micropores, the zeolite contains divalent metal cations, and the mass ratio of the trypsin to the zeolite is 1:200-4:10. In the...  
WO/2020/158847A1
The purpose of the present invention is to provide a medical base material for an indwelling cardiovascular device, wherein a special knitted structure, which is formed of multifilaments containing ultrafine fibers, can maintain antithro...  
WO/2020/061067A3
The disclosure relates to compositions and methods of treating, improving, and accelerating the healing of large segmental bone defects in a subject. The method comprises administering to a patient in need of treatment an effective amoun...  
WO/2020/144244A1
The present disclosure relates to an anticoagulant-coated microporous hollow fiber membrane showing reduced thrombogenicity. The disclosure further relates to a method for producing the membrane and a filtration and/or diffusion device c...  
WO/2020/136665A1
Present invention discloses preparation of covalent conjugate Heparin – polymer using carboxyl group of Heparin sodium and terminal hydroxyl and/or group of amino group of polymer. This attachment is conducted for increasing the compat...  
WO/2020/130466A1
Disclosed is a blood-compatible polymer represented by formula 1. A polymer in which fluorinated methacrylate is grafted to a polyvinylidene fluoride copolymer, according to an aspect of the present invention, is a polymer with blood com...  
WO/2020/122193A1
Provided is a medical device having adequate mechanical characteristics and exceptional non-adsorptivity with respect to biological components. This medical device comprises a base material and a film formed on the surface of the base ma...  
WO/2020/108670A2
Provided is a hemostatic composition comprising trypsin and zeolite, wherein pore channels of the zeolite are micropores, the zeolite contains divalent metal cations, and the mass ratio of the trypsin to the zeolite is 1:200-4:10. In the...  
WO/2020/105570A1
The present invention pertains to an alloy for medical use that comprises Pt, Co, Cr, Ni and Mo. This alloy comprises 10-30 atm% inclusive of Pt, 20-31 atm% inclusive of Cr, 5-24 atm% inclusive of Ni, 4-8 atm% inclusive of Mo and the bal...  
WO/2020/070258A1
There is provided inter alia an anticoagulant surface which surface has covalently bound thereto a plurality of fragments of heparin, wherein said fragments consist of 5-18 saccharide units and at least some of said plurality of fragment...  
WO/2020/045611A1
A goal of the present invention is to provide a cylindrical member for implantation that is capable of maintaining high patency through the achievement of antithrombotic properties, low swelling, and a low Young's modulus. The present in...  
WO/2020/039016A1
A vascular device (1) for insertion in a body lumen (7) comprises a surface (111), wherein at least a portion of the surface (111) is provided with double or more charged ions (112) such that the ions (112) are exposed to a bodily fluid ...  
WO/2019/170859A3
There is provided inter alia a solid object having a surface comprising a layered coating of cationic and anionic polymer, wherein the outer coating layer is a layer comprising cationic polymer to which is covalently bound an anticoagula...  
WO/2019/203898A1
A method of manufacturing a medical product having an engineered heparin bioactive matrix for clinical application on a blood contacting surface comprises: a) activating a blood contacting surface of at least one component of a medical d...  
WO/2019/195607A1
A deployment system and method of use thereof is provided for an interior driveline that mitigates the risk of infections for a variety of implanted medical appliances with a percutaneous conduit. The interior driveline and driveline dep...  
WO/2019/195056A1
Described herein are cell compositions comprising a mesenchymal stem function cell (MSFC), e.g., an engineered MSFC or derivatives thereof, as well as compositions, pharmaceutical products, and implantable elements comprising an MSFC, an...  
WO/2019/187860A1
[Problem] To provide a medical appliance that has excellent sliding properties (piercing characteristics) and is able to exert excellent antithrombogenicity. [Solution] This medical appliance has, at the surface, a coating comprising a c...  
WO/2019/188598A1
[Problem] To provide a medical appliance that has excellent slipperiness (in particular, piercing characteristics) and is able to exert excellent anti-thrombogenicity. [Solution] This medical appliance has, at the surface, a patchy struc...  
WO/2019/170858A1
According to the invention there is provided inter aliaaprocess for the manufacture of a solid object having a surface comprising a layered coating of cationic and anionic polymer wherein the outer coating layer comprises an anticoagulan...  
WO/2019/170859A2
There is provided inter alia a solid object having a surface comprising a layered coating of cationic and anionic polymer, wherein the outer coating layer is a layer comprising cationic polymer to which is covalently bound an anticoagula...  
WO/2019/142710A1
Provided is a medical coating material with which it is possible to form a continuous coating without exposing the substrate surface, especially on silicone rubber substrates. The medical coating material according to the present inventi...  
WO/2019/138412A1
Compositions comprising electrospun fibers and pharmaceutical agents encapsulated thereto are provided. Further, articles such as medical devices and methods of use of said fibers, including, but not limited to coating of medical tubes, ...  
WO/2019/129640A1
A biodegradable cardiovascular implant is provided for growing cardiovascular tissue in a patient. The implant distinguishes an electro-spun network with supramolecular compounds having hard-blocks covalently bonded with soft-blocks resu...  
WO/2019/078056A1
Provided is a curable composition that makes it possible to obtain a cured product having excellent adhesion to substrates and excellent biocompatibility. Also provided are a film and a cured product having excellent adhesion to substrat...  
WO/2019/077929A1
Provided is a curable composition that makes it possible to obtain a cured product having excellent adhesion to substrates and excellent biocompatibility. Also provided are a film and a cured product having excellent adhesion to substrat...  
WO/2019/079535A1
Described herein is the use of a methylated/sulfated hyaluronan, sulfated hyaluronan, or the pharmaceutically acceptable salt or ester thereof for the treatment of chronic rhinosinusitis.  
WO/2019/074791A1
In this work, a hydrophilic, yet slippery solid surface was developed. Because the surfaces are hydrophilic, there is significant affinity between the surface and contacting water, which results in substantial spreading of the contacting...  
WO/2019/065947A1
The purpose of the present invention is to provide a medical material using a nickel titanium alloy which reduces the thickness of a polymer electrolyte while supporting an antithrombotic compound in an amount sufficient to create a ther...  
WO/2019/057709A1
The present invention relates i.a. to compositions which are suitable for treatment of infertility or subfertility, in particular infertility or subfertility caused by polycystic ovary syndrome (PCOS)or anovulation, or which are suitable...  
WO/2019/046853A1
The disclosure concerns medical devices configured to utilize nitric oxide (NO) donor materials to release NO gas upon contact with moisture in order to mitigate bacterial proliferation, coagulation, or a combination thereof, at a site o...  
WO/2019/042261A1
Disclosed in the present invention are a composite heparin anticoagulation coating liquid, microspheres for a coating, a preparation method, and applications. In the present invention, by means of combined use of curcumin and heparin, th...  
WO/2019/035365A1
Provided is an article, which is an antibacterial article, a cell culture article, an antithrombotic article, or a biomedical article, to which proteins, blood components, cells and bacteria tend not to adhere. The antibacterial article,...  
WO/2019/010490A1
Provided herein are synthetic bioconjugates comprising collagen-binding peptides covalently bound to chemically modified glycan backbones, compositions containing the same, and uses thereof.  
WO/2019/007423A1
An implantable apparatus, comprising at least one corrodible zinc-containing portion, wherein a content range of zinc in the at least one zinc-containing portion is [30, 50) wt.% and zinc in the zinc-containing portion is an amorphous st...  
WO/2019/007400A1
Disclosed are a biodegradable film, a preparation method and the use thereof. The preparation method for the biodegradable film comprises placing a mobile phase made of a film-forming raw material in a dry, flat-bottomed container, solid...  
WO/2018/237166A1
High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and ot...  
WO/2018/233767A1
The invention relates to a coating or a body provided with a coating. The coating is at least partly made of a composite material which comprises a porous support that has a metal core surrounded with a metal oxide. According to the inve...  
WO/2018/197341A1
A fluorinated aromatic sulfone polymer [polymer (F-PS)] comprising: recurring units [units (A)] derived from at least one dihalo-diaryl sulfone [monomer (A)]; recurring units [units (B)] derived from at least one aromatic diol [monomer (...  

Matches 1 - 50 out of 4,156