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WO/2012/003130A2 |
A system for delivering a treatment agent such as a radioactive source 26 to a targeted treatment site within a patient's body is disclosed. Aspects of the device provided herein include a cable 42 with contiguous sections 44 and 46 havi...
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WO/2011/124780A2 |
The invention relates to a device (1) for preparing a syringe (S) equipped with a needle (7), said syringe (S) being housed in a sheath (F) for protection and gripping, said device being integrated in a metal-clad enclosure (3) provided ...
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WO/2011/116237A1 |
The present invention provides modified stem cells that comprise a delivery system that comprises at least one microparticle or nanoparticle, wherein the at least one microparticle or nanoparticle comprises an active agent. The present i...
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WO/2011/100586A1 |
Described here are brachytherapy applicators that comprise a modular support matrix. The modular support matrix may define the arrangement of radiation source lumens within the brachytherapy applicator. The modular support matrix can be ...
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WO/2011/053908A1 |
The present invention also features a brachytherapy system comprising a spiral cut tube having a first end and a second end; a radioactive brachytherapy source (RBS) disposed on the first end of the spiral cut tube; and a handle and a ge...
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WO/2011/043816A1 |
Tracers targeting phosphodiesterase1 for use in gamma radiation detection-based diagnostic techniques, particularly gamma-emitter labeled tracers for SPECT and positron emitter-labeled compositions for PET are disclosed. Radio-labeled mu...
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WO/2011/037615A1 |
A microfluidic radiopharmaceutical production system and process for synthesizing per run approximately one (1) to four (4) unit dose of a radiopharmaceutical biomarker for use in positron emission tomography (PET). The system includes a...
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WO/2011/017583A1 |
The present invention features compositions and methods for treating cancers such as melanoma, which have a subpopulation of self -renewing JARIDIB-positive cells essential to maintenance and metastatic progression of the cancer.
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WO/2011/011731A2 |
Systems and methods are provided for treating cervical and/or uterine cancers in brachytherapy with an intracavitary brachytherapy applicator. The system comprises a tandem adapted for insertion into a cervix of a patient. An ovoid assem...
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WO/2010/151429A2 |
A vaginal cervical retractor used to maneuver and visualize the uterus during various medical examinations and procedures would include an inner tube provided with a movable assembly of plastic cups (cervical cup and vaginal cup) designe...
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WO/2010/132428A1 |
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds. A preferred compound of the present invention has the following struc...
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WO/2010/101721A1 |
A rough, bio-absorbable strand is provided. More specifically, a bio-absorbable strand having a central body and a rough or irregular outer surface capable of securing the placement of the strand inside a patient is provided. The strand ...
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WO/2010/099126A2 |
A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling...
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WO/2010/078370A1 |
The present invention relates to methods of synthesizing 18F-radiolabeled styrylpyridine and its tosylate precursor. The present invention further relates to stable pharmaceutical compositions comprising 18F-radiolabeled styrylpyridine.
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WO/2010/059563A2 |
Disclosed herein are systems and methods related to aneurysm treatment. More specifically, the systems and methods disclosed herein relate to localized treatment of aneurysms utilizing polymeric micelles that release therapeutic agent(s)...
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WO/2010/042793A1 |
Brachytherapy apparatus and methods for performing brachytherapy employing expandable members with at least one external fixation element, offering precise therapy due to rotational and/or longitudinal stability of the expandable member.
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WO/2009/105473A9 |
A pneumostoma assessment and treatment system includes devices for aftercare of a pneumostoma and for additional patient care utilizing a pneumostoma. The system utilizes a number of medical devices and modalities to assess the health an...
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WO/2010/025396A1 |
A brachytherapy multiple needle loading device and method are provided. The device allows multiple implantation devices to be loaded at the same time and has a gating retention mechanism that allows the user to load sources into implanta...
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WO/2010/009186A1 |
The present invention features liposomal formulations composed of at least one hydrophilic pharmaceutical compound loaded in the aqueous core of the liposome and at least one hydrophobic pharmaceutical compound in the bilayer of the lipo...
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WO/2009/152320A2 |
A shielding assembly for an infusion system includes a plurality of compartments and a door for each compartment, and provides a radioactive radiation barrier for the compartments. One of the compartments contains one or more radioisotop...
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WO/2009/152440A1 |
The present invention describes small molecule ligand-drug conjugates and methods of using the small molecule ligand-drug conjugates for targeted treatment of cancer in a patient in need thereof. Further described are methods of steriliz...
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WO/2009/149175A1 |
A handheld radiation delivery system is disclosed that includes a two-part delivery module comprising a reusable portion that contains a radioactive source wire and a disposable portion that includes a drive assembly for moving the radio...
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WO/2009/126325A2 |
A brachytherapy applicator and method of use involve source guides that assume a desired curving, non-linear configuration. A flexible source catheter follows the shape of the source guides when inserted therein. Radiation dose received ...
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WO/2009/124257A2 |
Described herein are methods and devices for infusion of a radioactive compound, such as yttrium-90 radiolabeled somatostatin peptide or analog. A radiation shield defining a shielded cavity suitable for storing a radioactive substance i...
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WO/2009/117353A2 |
An instrument used for delivering a hemostat (210) including intermediate shaft (132) and an inner shaft (134) telescopically received therein, and an inflatable balloon (160) coupled to the distal ends thereof. The intermediate and inne...
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WO/2009/117357A2 |
An instrument (100) for controlling bleeding includes an outer shaft (112) an intermediate shaft telescopically received within the central lumen of the outer shaft, and an inner shaft telescopically received within the central lumen of ...
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WO/2009/111060A2 |
A vaginal brachytherapy applicator has an insertable tip section, preferably rigid or at least firm enough to retain its shape when inserted, and a tubular handle section extending proximally from the tip section. A common lumen extends ...
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WO/2009/106961A1 |
The hydraulic circuit for the injection of fluids for applications in medicine, particularly radioactive diagnostic fluids in nuclear medicine, comprises an infusion line associable with a patient, introduction means for introducing a pr...
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WO/2009/106977A1 |
Appliance for the injection of fluids for applications in medicine, particularly radioactive diagnostic fluids in nuclear medicine, which comprises a hydraulic circuit associable with a patient and automatic injection means for injecting...
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WO/2009/108380A2 |
Attenuating masks for selective attenuation of radiation, particularly from an x-ray source in brachytherapy, employ materials having atomic number in a specific range, so as to attenuate radiation dose intensity generally proportionally...
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WO/2009/102461A1 |
In a kyphoplasty procedure to expand and repair a damaged vertebra, diseased bone around the vertebral fraction zone is irradiated by use of a small radiation source inserted through the cannula used in the kyphoplasty procedure.
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WO/2009/091354A1 |
A brachytherapy appliance removably positionable on or against a surface of a living body, such as the body of a human or animal, for positioning a therapeutic delivery device in a desired precise location in relation to a selected porti...
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WO/2009/073698A1 |
A homogenous dispersion of aqueous droplets of a radiopharmaceutical or radiodiagnostic agent within a non-aqueous medium and method of making the same is provided. The homogenous dispersion is largely free of impurities and constitutes ...
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WO/2009/067203A1 |
A special photosensitizer formulation and Photodynamic Therapy method for treating choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD) is provided. CNV is a major cause for vision loss in elderly pat...
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WO/2009/066182A2 |
A method and composition for administering a therapeutic agent to a lesion comprising a contrast/carrier agent and ethanol.
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WO/2007/024715A9 |
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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WO/2009/045230A1 |
This invention provides a safer and more effective treatment for undesirable tissue masses, especially bone cancer and soft tissue tumors. The method involves a composition for direct administration of a therapeutic, radioisotope formula...
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WO/2009/027394A1 |
The present invention provides a kit for delivering catheter brachytherapy to a subject comprising a medical balloon catheter (1) having a proximal (2) and distal (3) end, comprising a elongated catheter tube (5) with an inflation lumen ...
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WO/2009/018383A1 |
Systems and methods for enhancing the selective targeting of agents (204) for preferential action at a target with reduced action with healthy tissue distal the target tissue. One or more agents (204) can be combined with nano scale stru...
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WO/2009/018332A1 |
The invention provides modified oligonucleotides of formula (I), comprising at least one metal chelator which provides a powerful tool for study of the pharmacokinetics of siRNA and its correlation with in vivo activity. The chelated met...
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WO/2009/015341A1 |
A seed anchor includes a tubular anchor body having a plurality of partial cylindrical walls splayed outwardly at an axial end of the anchor body to form an anchoring structure configured to resist axial movement of the seed anchor in a ...
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WO/2009/008988A1 |
Disclosed are intradermal^ administered products and methods for producing an immune response in a human or in an animal comprising an antigen and a polyphosphazene polyelectrolyte adjuvant in an amount effective to elicit an immune resp...
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WO/2009/005528A1 |
A cartridge may include a housing configured to contain a plurality of like items and a track inside the housing The tiack extends in a first direction, and a plunger may be slidable along the track in the fust direction and configured t...
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WO/2008/156503A1 |
This disclosure relates to compositions for delivering agents to a subject, and in particular, to compositions for delivery of therapeutic agents or diagnostic agents in the presence or absence of targeting moieties. In part, this disclo...
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WO/2008/140351A1 |
The invention relates to medical engineering. The inventive automated strontium-rubidium infusion system comprises a container with eluent, a strontium-rubidium generator with a filter and a pressure sensor and an eluate infusion unit, w...
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WO2008094199A9 |
The invention is a novel adaptive CT-friendly brachytherapy applicator with remotely-controlled radial and longicudinal motion radioactive source lumen shields that can be manipulated by the radiation oncologist to optimize the dose dist...
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WO/2008/134662A1 |
The present invention relates to biochemical methods for assessing metabolic fitness and/or aerobic demands of a living system. Specifically, the rate of synthesis and turnover of the molecular components of mitochondrial mass are used t...
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WO/2008/127897A1 |
Alkoxy[13C]methyl phenyl sulfone is a precursor to the production of Lithium (E)-β- Alkoxy[1,2,3-13C3]acrylate and thence Alkoxy (E)-β-Alkoxy[1,2,3-13C3]acrylate. Alkoxy (E)-β-Alkoxy[1,2,3-13C3]acrylate can then serve as a precursor f...
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WO/2008/124149A1 |
A system is provided for use in brachytherapy where a central tube permits passage of a radioactive source therethrough to deliver a prescribed dosage of radiation. One or more balloons are coaxially positioned around the central tube. A...
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WO/2008/115399A1 |
The disclosure is directed to radiation catheter devices, methods for controlled application of irradiation to tissue at a body site, such as a cavity formed after removal of tissue, e.g. cancer, using such radiation catheter devices, so...
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