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WO/2021/174039A1 |
Low-viscosity nucleic acid compositions that can be administered by oral or multiple parenteral routes may allow for less frequent dosing than nucleic acid products currently on the market. In particular, low-viscosity defibrotide formul...
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WO/2021/172696A1 |
A laser irradiation device according to the present invention is for treatment of the skin of a human body and comprises: a casing including a grip part and a barrel part; a laser oscillator accommodated in the casing and formed to gener...
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WO/2021/167143A1 |
The present invention relates to a tip for spraying a tattoo dye, the tip comprising: a pressure chamber configured to be able to accommodate liquid; a window provided on one side of the pressure chamber and provided to allow laser irrad...
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WO/2021/165141A1 |
A mold, more particularly a casting mold for producing microstructures, more particularly microneedle arrays, has a main part (10). A plurality of recesses (14) are provided on a top face (12) of the main part (10) and are intended to re...
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WO/2021/166977A1 |
Provided are a method for pretreatment of cell transplantation by which implants can be filled into a transplantation device at improved work efficiency, a device for pretreatment of cell transplantation, and a unit for pretreatment of c...
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WO/2021/167410A1 |
A microneedle patch according to an embodiment comprises: a body in which at least one opening is formed; and a microneedle body which is disposed in the opening and has at least one microneedle formed therein, wherein when an external f...
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WO/2021/166643A1 |
An access port (10) used in connection with a catheter (C) is equipped with a port body (11) that includes a liquid-holding portion (11a) and a diaphragm body (60) that covers the liquid-holding portion (11a). The port body (11) includes...
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WO/2021/166642A1 |
An access port (10) is used in connection with a catheter (C) and is provided with: a port body (11) including a liquid storage unit (11a); and a diaphragm body (60) held by the port body (11) and covering the liquid storage unit (11a). ...
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WO/2021/168351A1 |
A brain drug delivery system having a catheter and a delivery assembly is provided. The catheter has a first channel with a first exit hole and a second channel with a second exit hole, both the first exit hole and the second exit hole b...
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WO/2021/168479A1 |
A wound closure device includes an elastic substrate and one or more microstructure arrays coupled to the elastic substrate via an adhesive layer. The device is long enough or wide enough to treat large wounds.
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WO/2021/164979A1 |
A microneedle array has a plurality of microneedles (10), said microneedles being supported by a substrate. In order to improve the properties of the microneedle array, the substrate is in the form of a grid structure (12, 14) or compris...
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WO/2021/168345A1 |
The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to ac...
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WO/2021/162068A1 |
This transfer device for a living body is for placing an object within a living body and is provided with a plurality of movable units. Each movable unit is provided with one or more needle-shaped parts extending in a first direction. Ea...
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WO/2021/161072A1 |
A leech therapy device adapted to latch a medicinal leech to a predetermined wound site is provided. The leech therapy device incudes a conduit extending between a first end to a second end; an inner diameter of the conduit dimensioned t...
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WO/2021/146428A9 |
Provided herein are microbubble compositions comprising nitro-fatty acids and/or esters thereof, such as amphiphilic esters or allyl esters thereof. Also provided are methods of reducing local inflammation at a site in a patient comprisi...
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WO/2021/157488A1 |
Provided is a method for manufacturing a sterilely manufactured product, in which a drying container can be reused. A first polymer-dissolved solution (22) is accommodated in a first drying container (28) composed of a container main bod...
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WO/2021/158821A1 |
Disclosed herein are aesthetic-enhancing formulations and methods thereof. For example, an aesthetic-enhancing formulation includes, in some embodiments, one or more pigments, one or more active ingredients, and one or more excipients. T...
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WO/2021/155203A1 |
A system and method for controlling a renal therapy device is provided. The system comprises a controller for performing a method comprising: receiving a first power level of a first battery to determine if the first power level of the f...
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WO/2021/154873A1 |
A wirelessly powered tattoo machine is disclosed, which has a substantially radially symmetric exterior shape for optimal manipulability by a user, and integrated controls for on-device configuration and operation. The power supply compo...
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WO/2021/154927A1 |
Disclosed herein are systems and methods for the injection of viscous fluids. For example, inventive systems and methods for injecting viscous fluids, such as concentrated drug formulations, via droplet lubrication are described.
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WO/2021/153279A1 |
A medical device 1 that is used by being implanted in the body, wherein the medical device 1 comprises a body part 11, a container 12 included in the body part 11, an insulating flexible part 13 that closes off an opening of the containe...
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WO/2021/144472A1 |
The present invention relates to a method of a method of measuring a human body analyte concentration in an interstitial fluid, comprising the step of measuring a first electrical current h between a working electrode and a pseudo-refere...
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WO/2021/143951A2 |
The present invention relates to the field of microneedle-array transdermal drug delivery, specifically to a colchicine-containing soluble microneedle patch and a preparation method therefor. The microneedle patch comprises a hyaluronic ...
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WO/2021/138714A1 |
A method and apparatus for enhanced delivery of therapeutically active, cosmetic or skin care agents onto membrane surfaces by use of a combination of magneto-wetting and electro-wetting on ultrasonically generated diamagnetic droplets, ...
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WO/2021/138713A1 |
A method and apparatus for enhanced delivery of haircare active agents onto hair surfaces by use of a combination of magneto-wetting and electro-wetting on ultrasonically generated diamagnetic droplets, including enhanced delivery of sub...
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WO/2021/138715A1 |
A method and apparatus for enhanced delivery of fluid compositions onto target surfaces by use of a combination of magneto-wetting and electro-wetting on ultrasonically generated diamagnetic droplets.
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WO/2021/142160A1 |
A gelatin-based (e.g., gelatin methacryloyl (GelMA)) patch is disclosed with an array of microneedles (MNs) for minimally invasive sampling of bodily fluids such as interstitial fluid (ISF). The properties of the patch can be tuned by al...
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WO/2021/141304A2 |
A microneedle applicator is provided. A microneedle applicator according to an embodiment of the present invention comprises: a microneedle array; an operation member disposed on the upper portion of the microneedle array and operating s...
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WO/2021/137236A1 |
A three-dimensional biomatrix embedded with an anticancer drug and having an inherent ability to induce bone regeneration and/or to inhibit bone degeneration and uses of same for treating, ameliorating or inhibiting progression of bone c...
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WO/2021/135359A1 |
A unilateral-driven patch-type drug infusion device, comprising: an infusion unit, which includes a drug storage unit (1110); a screw (1130) connected to a piston (1120) and a driving wheel (1140) provided with wheel teeth (1141), respec...
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WO/2021/136933A1 |
The present invention relates to the field of cancer therapy. In particular, the present invention relates to a method of preventing, treating or inhibiting the development of tumours and/or metastases in a subject by administering one o...
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WO/2021/132787A1 |
A skin care device according to an embodiment of the present invention comprises: a main body comprising a battery and a grip electrode electrically connected to the battery; and a head connected to one end of the main body, wherein the ...
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WO/2021/132100A1 |
The purpose of the present invention is to provide a method for producing a microneedle device that has a coating containing dexmedetomidine and isoproterenol, the method providing high isoproterenol stability during and after the produc...
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WO/2021/127721A1 |
A hand-held tattoo machine, comprising: a body; a power supply integrated within the body; a control system integrated within the body; a user input interface on the body to receive input from a user holding the tattoo machine; and a nee...
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WO/2021/127720A1 |
A hand-held tattoo machine, comprising: a body; a control system; a user interface to receive input from a user holding the hand-held tattoo machine; and a needle assembly comprising at least one needle which is driven by the control sys...
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WO/2021/132022A1 |
Provided is a microneedle array production method with which microneedle arrays provided with needle-shaped protrusions having a constricted shape can be efficiently and stably produced. This microneedle array production method comprises...
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WO/2021/133440A1 |
Methods to treat anemia are provided whereby an erythropoietin stimulating agent (ESA) and an iron supplement are administered by a wearable device, based on patient parameters sensed by the wearable device. The method can involve monito...
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WO/2021/126951A1 |
A medical device comprising a housing defining at least one enclosure for storing agent in a first form, a force applicator within the housing and adjacent the enclosure, a drive mechanism for moving the agent toward the force applicator...
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WO/2021/125955A1 |
A reusable applicator for applying a microneedle patch to a skin of a subject which comprises a base for positioning onto the skin. The base comprises a skin-side end and a holder for holding the microneedle patch in position relative to...
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WO/2021/121589A1 |
An applicator for applying a microneedle patch to a skin of a subject, comprising a base having a skin-side end and a holder for holding the microneedle patch. Two or more contact parts are movable over the skin and away from each other ...
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WO/2021/125067A1 |
The present invention relates to a cosmetic process for a keratin substance such as the skin or the lips, comprising the steps of: applying onto the keratin substance at least one composition comprising at least one coloring agent; and a...
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WO/2021/121638A1 |
Transdermal drug delivery devices are described herein such as a microneedle array patch, to be placed on the skin for transdermal delivery of a medicament. The transdermal drug delivery device for delivery of a bioactive agent through m...
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WO/2021/123736A1 |
The invention concerns improvements in needle-free devices for delivery of therapeutic and/or prophylactic agents, such as solid dose drugs, including vaccines. The needle-free device disclosed herein comprises novel structural arrangeme...
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WO/2021/119347A1 |
A cold atmospheric plasma (CAP)-mediated ICB therapy/delivery device are disclosed herein that employs a patch having microneedles that are used to deliver the CAP transdermally along with an immune checkpoint inhibitor for enhancing tra...
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WO/2021/119022A1 |
A rotary tattoo machine includes an inner housing; a tattoo needle; an electric motor including a shaft assembly; and a bearing arm including a bearing. The machine also includes a cam, the cam moving up and down the shaft assembly due t...
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WO/2021/118205A1 |
The present invention relates to an implantable medical device capable of releasing an anti-inflammatory substance and, particularly, to an implantable medical device, which releases anti-inflammatory drugs while inserted in the body, so...
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WO/2021/119478A1 |
Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending ...
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WO/2021/119025A1 |
Embodiments of a method for removing a tattoo through patterned trans-epidermal pigment release includes determining first treatment area of skin of a patient through a primary template including primary apertures, marking the first trea...
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WO/2021/119332A1 |
A delivery device or patch is disclosed that includes a detachable hybrid microneedle depot (d-HMND) for cell delivery. The system includes, in one embodiment, an array of microneedles formed from an outer PLGA shell and an internal gela...
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WO/2021/109005A1 |
A drug administration connector (100) and a drug administration device (200). The drug administration connector (100) comprises: a drug administration connector body (1), the interior of which is hollow, one end of the drug administratio...
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