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WO/2024/000015A1 |
An electrochemical sensor apparatus for introducing a needle electrode into the skin of a subject to contact a biological fluid or a tissue in the subject and detect a target analyte. The apparatus has a movable portion which urges the n...
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WO/2024/000017A1 |
An electrochemical sensor apparatus for introducing a needle electrode into the skin of a subject to contact a biological fluid or a tissue in the subject and detect a target analyte. The apparatus has a movable portion which urges the n...
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WO/2023/246262A1 |
The present invention provides a method for preparing a microneedle drug membrane, comprising the following operations of: detachably placing a disposable screen plate on a forming mold, the disposable screen plate being provided with a ...
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WO/2023/250117A2 |
Patch applicator devices are provided. The devices can include a reusable or single-use system for applying a push-through or breakaway patch to a patient's skin. The devices can improve application and effectiveness of microneedle based...
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WO/2023/246475A1 |
The present invention provides a vibration structure for hyaluronic acid injection and a device for hyaluronic acid injection. The vibration structure comprises a linear motor, a vibrating rod, a motor housing, and a microcrystalline sea...
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WO/2023/242182A1 |
A system (1) for administering an active ingredient, comprising a magnetizable core (2), wherein the core (2) has a sheath (3) of silicon dioxide, characterized in that the sheath (3) completely surrounds the core (2), wherein the core (...
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WO/2023/241422A1 |
Provided are a roller (a), a microneedle roller (b), and a nursing instrument (c). The roller (a) has a rolling peripheral surface, the rolling peripheral surface can rotate around a rotation axis (L), and at least one loading plane (1) ...
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WO/2023/244207A1 |
The invention relates to a method of manufacturing microneedle patches for transdermal drug delivery using dynamic light processing (DLP) technique using Gelatin Methacrylate (GelMA) or a mixture of Gelatin Methacrylate (GelMA) + Keratin...
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WO/2023/241088A1 |
The present invention relates to the technical field of production devices of microneedle patches for medical and cosmetic purposes, and provides a microneedle patch base layer lamination and separation device and a control method theref...
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WO/2023/236973A1 |
A hydrogel microneedle patch based on a three-dimensional scaffold structure, a preparation method for a microneedle patch, and a use thereof. The microneedle patch comprises microneedles; raw materials of the microneedles comprise polyv...
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WO/2023/240203A1 |
Disclosed herein are patches, methods, devices, and systems for delivering a non-aggregating peptide, such as alcadein and its fragments, into a subject. In some aspects, the patch includes a backing, a matrix comprising a non-aggregatin...
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WO/2023/238345A1 |
To provide a novel microneedle device which reduces the hassle of hydrating the skin in advance. A microneedle device 100 comprises an adhesive layer 1 and a microneedle sheet layer 10, wherein the adhesive layer 1 has one or more openin...
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WO/2023/236845A1 |
The present invention provides a vibration structure for hyaluronic acid injection and a device for hyaluronic acid injection. The vibration structure comprises a rotating motor, a converting member, a vibrating rod, and a microcrystalli...
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WO/2023/236765A1 |
A microneedle roller (A) and a container (T). The microneedle roller (A) comprises a roller unit (a), a first assembly part (b1), and a second assembly part (b2). The roller unit (a) comprises main disks (a1) and spacers (a2) arranged at...
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WO/2023/235298A1 |
The disclosure provides methods for reducing a thermal start-up burst release from an implantable device for controlled release of a therapeutic agent from a device comprising a capsule configured for implantation and having a reservoir....
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WO/2023/232780A1 |
A felting set (1) for attaching an implant (10) to soft tissue (2). The set comprises a felting device (20) and the implant, wherein the implant comprises a patch comprising a non-woven material made of individual fibers (11), wherein th...
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WO/2023/234381A1 |
A transfer instrument (10) facilitates the transfer of a medical sheet (300) to a transplantation target part (402) of a heart (400). The transfer instrument (10) comprises: a first carrier member (18) including a first shaft (24) and a ...
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WO/2023/234380A1 |
This transfer instrument (10) transfers a medical sheet (300) to a transplant destination part (402) of a heart (400). The transfer instrument (10) comprises: a first carrier member (18) which has a first support part (26) and a first sh...
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WO/2023/229079A1 |
A mold support unit is disclosed. The mold support unit supports molds for manufacturing microstructures, and comprises a support plate in which a plurality of support regions on which the molds are placed are formed to be spaced apart f...
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WO/2023/226160A1 |
A super-swelling microneedle patch, comprising a microneedle and a substrate matched with the bottom of the microneedle. The microneedle is made of a cross-linked hydrophilic polymer; the substrate is made of a hydrophobic polymer; and t...
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WO/2023/226136A1 |
A microneedle system for diagnosis and treatment of brain diseases and a preparation method therefor. The microneedle system for diagnosis and treatment of brain diseases comprises 0.1-10 parts of an active pharmaceutical ingredient lipo...
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WO/2023/227003A1 |
Provided are a method for preparing a microneedle patch, a forming mold (1), and an alignment fit device (7). The method comprises the following procedures: filling a forming mold (1) with a forming liquid, wherein the forming mold (1) c...
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WO/2023/229290A1 |
The present invention relates to a microneedle and method for manufacturing the microneedle and, more specifically, to: a microneedle in which by a structure of a recess part of the microneedle, a coating amount of a drug can be increase...
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WO/2023/228378A1 |
A biological tissue attachment patch 1 comprises a battery unit 2 and soluble microneedles that contact the battery unit 2. The soluble microneedles 3 include an active ingredient. A battery reaction is started by inserting the soluble m...
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WO/2023/225101A1 |
Microneedle patches that include a backing layer, and an array of microneedles extending from the backing layer, wherein the microneedles each include a core portion which includes a drug, and a shell portion and a cap portion, wherein t...
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WO/2023/225222A1 |
Various example of the present disclosure provide sensing apparatuses configured for wearable and wireless use for deep tissue physiological monitoring. The sensing apparatuses may be embodied by a thin flexible patch configured to confo...
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WO/2023/224422A1 |
A microneedle therapy device including a needle cover according to one embodiment of the present invention comprises: a pneumatic pump; a valve which opens and closes the supply of compressed air into the needle cover of the pneumatic pu...
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WO/2023/224197A1 |
The present invention relates to a micro-structured body employing a gyroid form in triply periodic minimal surface (TPMS) structures by using two-photon polymerization (TPP), and to a driving method therefor. The use of the present inve...
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WO/2023/224198A1 |
The present invention relates to a dispenser for electroporation comprising a disposable cartridge, the dispenser being supplied with a voltage from a main body and performing electroporation and drug injection into a target to be electr...
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WO/2023/220479A1 |
Systems, methods and apparatus for atomizing a topical and spraying both a user's skin and a microneedle roller. The microneedle roller can be off-axis from a needle axis thereby allowing the roller to either precede atomized topical rea...
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WO/2023/218230A1 |
The present invention relates to a dissolvable microneedle patch comprising a plurality of microneedles assembled on a substrate, which is made of a material having liquid-permeable cavities, wherein the microneedle comprises a needle ti...
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WO/2023/217747A1 |
A microneedle for transdermal drug delivery, the microneedle comprising an input channel extending through the microneedle along a longitudinal axis of the microneedle, the input channel defining a sidewall, a first end, and a second end...
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WO/2023/214209A1 |
A transdermal patch for delivering a vitamin B12 comprising at least three layers is developed. The transdermal patch comprises a first layer comprising at least one side adhesive surface configured to adhere to the skin, a second layer ...
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WO/2023/214581A1 |
Provided is an applicator which is equipped with a measure for alleviating pain that occurs when a microneedle formulation is applied to skin and/or a measure for improving a puncture property, and to which a microneedle formulation of n...
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WO/2023/214406A1 |
A device for multisite injection is disclosed. The device comprises, a first container in fluid connection with at least two needles; a second container in fluid connection with at least one needle; and an injection unit configured to in...
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WO/2023/214362A1 |
The present invention relates to a process for producing a three-dimensional structure comprising the steps of: a) providing a light source; b) coupling said light source to a proximal end of at least one optical fibre, in such a way as ...
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WO/2023/205341A1 |
Aspects of the present disclosure include polymeric structures having one or more polymeric microneedles. Polymeric structures according to certain embodiments exhibit a macrostructural change (e.g., exhibit elastic deformation) in respo...
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WO/2023/203462A1 |
The invention relates to a lancet (10) extending along a longitudinal axis (X) and comprising a head (11) that is suitable for being fixedly or detachably connected to, or formed as one piece with, a gripping means (12); the head compris...
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WO/2023/205496A1 |
A system for tracking the location of an anatomical structure, the system comprising: a J- bar and electrical lead assembly comprising: a J-bar comprising a tracker, a distal electrical connector formed on the tracker, and at least one m...
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WO/2023/197672A1 |
The present invention relates to a planar microneedle comprising a base layer and a microneedle. The microneedle comprises a needle tip, a middle part, and a needle base. The microneedle further comprises a first side wall, a circumferen...
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WO/2023/193798A1 |
Provided is a low-temperature-spraying and ultrasonic-introduction beauty system (1), comprising a beauty device (2) and a computing device (3). The beauty device (2) comprises: an image acquisition unit (26) configured to acquire an ima...
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WO/2023/194999A1 |
Disclosed herein are flexible microneedle arrays with improved characteristics, such as durability and high drug loading. Further disclosed methods of manufacturing the microneedle arrays, and uses thereof in treatment of a disease or a ...
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WO/2023/193089A1 |
A medical system includes a therapeutic fluid supply containing a therapeutic drug and a medical device in fluid communication with the therapeutic fluid supply. The medical device includes an expandable element and an injection tube cou...
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WO/2023/195666A1 |
A drug injection device of the present invention may comprise: a lumen part for forming an internal channel and an external channel; a gas part for supplying gas to the internal channel; and a medical liquid part for supplying a drug to ...
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WO/2023/196674A1 |
An automated external defibrillator (AED) system includes shock generating electronics configured to provide at least one electrical shock suitable for a patient experiencing a cardiac event, a battery configured for providing power to t...
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WO/2023/193422A1 |
Provided are a silicon-based ice microneedle and a preparation therefor. The silicon-based ice microneedle comprises a silicon wafer (10) and several micron needle-shaped structures (20) formed on the silicon wafer (10) and distributed i...
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WO/2023/193384A1 |
Provided is a beauty device (100), comprising a housing (10), a storage container (30), an applying/massage unit (40), and a driving unit (50). A mounting cavity is provided in the housing (10). The storage container (30) is provided in ...
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WO/2023/186923A1 |
The present disclosure is directed to an externally controlled, implantable, agent delivery device (310), a system including such a device, and methods for treating an internal disorder or disease, diagnosing, and/or imaging an organ or ...
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WO/2023/192143A1 |
The disclosure relates to the continuous monitoring, with contact, or contactless, of the cerebrospinal fluid (CSF) using dedicated sensor(s) assemblies. Specifically, the disclosure relates to assemblies, systems, uses and methods for c...
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WO/2023/190910A1 |
This microneedle structure 10 comprises a needle-shaped part 12 having a hole 13 formed in the interior thereof. The needle-shaped part 12 contains a resin and a filler 21. Such a microneedle structure can be configured to have a needle-...
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