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WO/2022/025319A1 |
The present invention relates to a soluble microneedle patch containing a skin-permeable recombinant neuropeptide complex, has superior skin permeability, and thus is highly effective in alleviating wrinkles and improving skin elasticity.
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WO/2022/020878A1 |
The present disclosure provides an agent delivery device (1) for delivery of a therapeutic agent or medicinal agent to an individual. The agent delivery device (1) comprises: a frame (2) having at least one frame member (4) configured to...
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WO/2022/018532A1 |
An apparatus includes a body configured to be at least partially implanted on or within a recipient and a plurality of electrodes positioned along the body. The plurality of electrodes includes a first set of electrodes configured to app...
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WO/2022/020354A1 |
Pressure waves are applied to intersect a focal volume or pressure field with a targeted tissue in conjunction with introducing a treatment agent into the targeted tissue to increase permeability of cells in the targeted tissue and cause...
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WO/2021/013907A9 |
A capsule device suitable for insertion into a lumen of a patient, the lumen having a lumen wall, wherein the capsule device (100, 200, 300, 400, 500) comprises a) a capsule housing (110, 120, 210, 220) having an outside shape formed as ...
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WO/2022/020427A1 |
A dissoluble microneedle drug delivery system includes a fixation component having an opening window area, and at least two replaceable and/or dissoluble inner matrices fitting into the window area one after another. The fixation compone...
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WO/2022/014695A1 |
The present invention addresses the problem of providing a preventive agent for Japanese encephalitis and a Japanese encephalitis vaccine that are capable of giving humans adequate immunity even with a dose smaller than that for a subcut...
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WO/2022/015329A1 |
A kit system has a beginning level kit apparatus, an intermediate level kit apparatus, and an advanced kit apparatus. The beginning level kit apparatus has a first derma roller having a head with a plurality of needles each having a leng...
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WO/2022/015071A1 |
The present invention relates to a method for inducing the death and suppressing the growth of bacteria causing infection from the skin during a surgical operation, by means of a local change in pH resulting from the degradation of biode...
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WO/2022/012520A1 |
The microneedle array (10) includes a substrate (12) having a central opening (14) formed therethrough, and a plurality of microneedles (18) positioned about a perimeter (16) defining the central opening (14). At least one of the microne...
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WO/2022/015326A1 |
A three-step process performs, with a derma roller, a plurality of movements along an area of intended rejuvenation of a human user. Furthermore, the three- step process applies, subsequent to the derma roller performance, a chemical com...
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WO/2022/009026A1 |
The present invention is aimed at solving the problem of pain during acupressure massage or acupressure reflexotherapy with applicators at the initial stages, so that the patient can get used to unpleasant sensations, or acclimate to mas...
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WO/2022/010057A1 |
A sample collecting device having microneedles, according to the disclosed present invention, comprises: a body part capable of entering a collection location at which a sample is to be collected; and at least one collecting part provide...
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WO/2022/008878A1 |
A device (1) for introducing microneedles (4) into the skin of a subject; and a method for inserting microneedles into the skin of a subject comprising use of said device.
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WO/2022/005177A1 |
The present invention provides an apparatus and method for manufacturing microneedles using electrohydrodynamic printing, the apparatus comprising: a substrate on which printed microneedles are placed; a nozzle unit that receives a bioco...
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WO/2022/004876A1 |
Provided is a liquid injection device 1 for injecting a liquid into skin via a microneedle 10, the device being constituted from a cartridge unit 20 and a body 30. The cartridge unit comprises: a microneedle; a jetting hole 11 for jettin...
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WO/2022/005071A1 |
The present invention relates to a microneedle comprising a microfiber network structure, and more specifically, to a microneedle which has an insoluble microfiber network structure incorporated in a dissolving microneedle, and thus, wit...
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WO/2022/003653A1 |
A multi-layer microneedle structure and a method for manufacturing same are provided. The multi-layer microneedle structure according to an embodiment of the present invention includes: a base layer formed on a support; a core layer form...
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WO/2021/262655A1 |
A grip apparatus or kit, and methods of use thereof, that includes a grip housing having a cartridge receiving portion and a motor housing mating portion at opposite ends. The cartridge receiving end having dimensioned to receive a needl...
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WO/2021/261554A1 |
A medical puncture needle (10) includes: a body section (14) in which an inner cavity (12) through which a chemical solution flows is formed in the interior thereof; a needle tip section (16) that protrudes from the body section (14) tow...
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WO/2021/258762A1 |
An ultrasound-guided drug-loaded microbubble delivery method and apparatus, and an electronic device and a computer-readable storage medium. The method comprises: step 110, sending a first ultrasound wave signal by using an array transdu...
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WO/2021/257837A1 |
An electronically power-adjusted tattoo machine, power supply, and methods for controlling needle reciprocation are disclosed. The dynamic power adjustment controls needle impact force of a tattoo machine through electronic circuitry whi...
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WO/2021/257737A1 |
Systems and methods for measuring vitals in accordance with embodiments of the invention are illustrated. One embodiment includes a method for measuring vital signs. The method includes steps for identifying regions of interest (ROIs) fr...
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WO/2021/256731A1 |
A needle assembly manufacturing jig according to an embodiment of the present invention comprises: a jig base substrate (100); a needle insertion plate (200) which is positioned on the jig base substrate (100) and into which a plurality ...
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WO/2021/256214A1 |
The present invention relates to a kit comprising: at least one microneedle sheet (1) comprising a substrate layer and a plurality of microneedles on the substrate layer, the microneedles comprising at least one water-soluble or water-di...
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WO/2021/253465A1 |
Disclosed are a microneedle casting system and a microneedle fabrication method, comprising a vacuum chamber, a motion platform, a first motion assembly, a liquid-filling needle assembly, a second motion assembly, and a controller; the m...
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WO/2021/252292A1 |
An applicator can include a dispenser for dispensing an amount of a therapeutic composition, which can include an amount of sugar or sugar alcohol and an amount of an alkalizing agent. In some cases, the alkalizing agent can include L-Ar...
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WO/2021/252673A1 |
Chimeric antigen receptor T cells (CAR T) therapy reached a milestone in eradicating Bcell malignancies, but beneficial effects in solid tumors are not obtained yet. A porous microneedle patch is disclosed that carries CAR T cells to sol...
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WO/2021/251464A1 |
This applicator for puncturing the skin with a microneedle array (4) is provided with: a holding unit (211) for holding the microneedle array (4); and a puncture promotion unit (223) that forms a puncture completion state in which a cent...
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WO/2021/253000A1 |
Described is a mixing syringe for receiving a removable carpule partitioned to form two reservoirs independently containing anesthetic solution and buffering solution and having a mixing chamber for mixing the solutions during administra...
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WO/2021/246618A1 |
The present invention relates to a skin peeling device comprising a main body, a hose connected to the main body, and a handpiece connected to the hose. The handpiece includes a head part and a handle part, and the head part and the hand...
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WO/2021/245346A1 |
Disclosed is a microneedle applicator for applying a fluid product to the skin and causing said fluid product to penetrate the skin, the applicator comprising: - an application face (AO) provided with at least one fluid product outlet (O...
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WO/2021/247846A1 |
Disclosed is an ophthalmic implant system including a first or primary device, which may be an intraocular lens assembly or other intraocular implant, and a secondary device comprising a drug delivery device. The drug delivery device is ...
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WO/2021/244630A1 |
A heat-resistant implantable polymer microneedle and a preparation method therefor and an application thereof. The microneedle comprises a needle tip, a needle body, and a base; the needle tip contains a homogeneous system formed by mixi...
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WO/2021/244435A1 |
A radio frequency micro-needle array control device and method, and a radio frequency micro-needle therapeutic apparatus. Said device comprises: a micro-needle array (30); an on/off switching circuit (40), an input end of the on/off swit...
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WO/2021/246731A1 |
A device inserted into a living body to generate an anticancer material is disclosed. The disclosed device comprises: an electric energy conversion module which receives an external signal to convert the external signal into electric ene...
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WO/2021/245348A1 |
Disclosed is a microneedle applicator for applying a fluid product to the skin and causing said fluid product to penetrate the skin, the applicator comprises: - an application face (PO) provided with a fluid product outlet (O) and a plur...
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WO/2021/247544A1 |
A method for applying ultrasound to activate a cavitation enhancing agent in the presence of a therapeutic compound and a microbial biofilm is provided. The ultrasound energy causes the cavitation enhancing agent to cavitate in the ultra...
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WO/2021/246301A1 |
Provided is a novel means for administering a valuable substance having a fat-dissolving effect. A microneedle preparation containing any one or more of a lipolysis agent, a fat-dissolving agent, or a fat metabolism promoter, for the p...
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WO/2021/248054A1 |
The present invention provides a method for treating a condition or disease in a subject, comprising administering to the subject's skin a composition comprising an effective amount of one or more bioactive formulations and compositions,...
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WO/2021/237310A1 |
The present invention relates to agent delivery systems for application to biological tissues. More specifically, the present invention relates to devices and methods for the non-invasive delivery of agents (e.g. pharmaceuticals and the ...
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WO/2021/241486A1 |
Provided is a micro-needle array of which all the fine needles can be more easily inserted into the skin regardless of the positions where the fine needles of the micro-needle array are located on a substrate. The micro-needle array co...
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WO/2021/235666A1 |
The present invention relates to a tattooing device which further includes a driving member having a weight balance in order to minimize vibrations of an eccentric member that eccentrically rotates in a handpiece main body, such that a u...
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WO/2021/231573A1 |
A cradle made of radiation-shielding material holds one or more radioactive seeds. The cradle surrounds all but a portion of the seed, and the potion of the cradle that does not surround the seeds creates an aperture through which the ra...
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WO/2021/229117A1 |
The invention relates to a wearable device for transdermal product supply, comprising a head (3) which houses two ultrasonic resonators (1,2) in resonance and has an outer cavity (6). A first, more distal resonator (1) emits towards the ...
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WO/2021/230582A1 |
The present invention relates to a drug injection device having a reciprocating needle, the drug injection device comprising: a main body; an injection port formed through an outer circumferential surface of the body; a drug chamber in c...
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WO/2021/225983A1 |
A method and apparatus for promoting the delivery of a molecule across a cell membrane comprises delivering a molecule to a delivery site of a region of tissue surrounding the cell membrane. A suction component applies a suction through ...
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WO/2021/221972A1 |
A microneedle assembly that is capable of delivering a drug compound (e.g., vaccine) and/or detecting the presence of an analyte is provided. The assembly comprises at least one microneedle extending outwardly from a support. The microne...
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WO/2021/221973A1 |
A microneedle assembly that is capable of transdermal delivery of a drug compound, such as a vaccine, (e.g., vaccine) across a dermal barrier of a subject (e.g., human), and/or detecting the presence of an analyte in the subject is provi...
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WO/2021/218107A1 |
A sleep mask for treating visual fatigue, comprising a sleep mask body (1); a connecting strip (2) is provided on each of the two sides of the sleep mask body (1), one or more iron pieces (3) are provided at intervals on the inner surfac...
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