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Patent Searching and Data


Matches 1 - 50 out of 95,074

Document Document Title
WO/2021/092496A1
Provided herein are thiazolidinedione analogues that are useful for treating non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), diabetes, and other metabolic inflammation-mediated disease and disorders. Furt...  
WO/2021/062631A9
Dentifrice compositions for treating dental plaque biofilm comprise zinc lactate, glycine, and fluoride ion.  
WO/2021/092487A1
Gastric residence systems and methods of delivering a drug to an individual using a gastric residence system are described herein. The gastric residence system may include a time-dependent and/or enteric, or dual time-dependent and enter...  
WO/2021/090228A1
The present invention relates to compositions for use in increasing the blood bioavailability of amino acids derived from proteins, preferably proteins of plant origin, wherein said compositions comprise a mixture M comprising or, altern...  
WO/2021/088957A1
Disclosed are a novel aromatic heterocyclic compound as an ATX (Autotaxin) inhibitor, a pharmaceutical composition containing the compound, and a use of the compound and the composition in treatment of a disease having a pathological cha...  
WO/2021/091188A1
The present invention provides a sustained-release pharmaceutical composition for oral administration once or twice a day, containing rebamipide or a pharmaceutically acceptable salt thereof, and chitosan as an anti-gelling agent and a s...  
WO/2021/089011A1
Provided are a compound with a bishydrazide structure represented by formula I, and a preparation method therefor and the use thereof. The compound with a bishydrazide structure can enhance the activity of intestinal stem cells, promote ...  
WO/2021/090245A1
The present technology provides pyrrolidine and piperidine compounds or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. In particular, said comp...  
WO/2021/092515A1
Disclosed herein include methods, compositions, and kits suitable for use in the spatial and temporal delivery of payload molecules to a target site of a subject. Disclosed herein include hydrogel compositions (e.g., particles) comprisin...  
WO/2021/090345A1
Composition for the treatment of intestinal gas and bloating, based on simethicone as an anti-foaming agent, acts on the symptoms of intestinal bloating and on the phenomena at its origin, thus preventing its formation. This allows to fu...  
WO/2021/091009A1
The present application discloses a method for screening an inflammatory bowel disease therapeutic agent on the basis of a mechanism in which RORα inhibits NF-κB transcriptional activity in the bowels, thereby inhibiting the expression...  
WO/2021/091846A1
The present disclosure relates to the use of Compound (I) or a pharmaceutically acceptable salt thereof, for the treatment of mast cell diseases and eosinophilic disorders.  
WO/2021/088999A1
A compound having therapeutic efficacy for liver disease. The compound may be the compound as represented by formula (I), an optical isomer of same, or a pharmaceutically acceptable salt thereof. The compound is applicable in the treatme...  
WO/2021/089300A1
The present invention relates to compounds 4-[5-[(rac)-1-[5-(3-Chlorophenyl)-3- isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine (TT00, TT001 and/or TT002), or a pharmaceutical composition comprising said TT00, TT001 and/or TT0...  
WO/2021/089580A1
The invention relates to an immediate release oral formulation of X842 comprising only limited amounts of surfactant. The invention also relates to the use of the oral formulation in the treatment of gastrointestinal inflammatory disease...  
WO/2021/088460A1
A method for preparing a probiotic-carrying microcapsule, a product prepared therefrom, and an application thereof. The method comprises the steps of: (1) dissolving sodium alginate in a solvent to obtain a sodium alginate solution; (2) ...  
WO/2021/088739A1
A method and a device for determining an intestinal probiotic supplement formula, a storage medium, and a processor. The method comprises dividing intestinal probiotics into a plurality of probiotic groups, and dividing each probiotic gr...  
WO/2021/083970A1
The invention also relates to a microbial strain selected from the genus of Kazachstania spp, Acetobacter spp. and/or Stenotrophomonas spp for use as a medicament, (i) a cellular extract from a strain selected from the genus of Kazachsta...  
WO/2021/085640A1
The present invention provides an agent that is for inhibiting the decrease of muscle mass and that is characterized by containing a ghrelin receptor agonist as an active ingredient and by being used for administration during a fasting p...  
WO/2021/085291A1
The purpose of the present invention is to provide: a composition for TGR5 activation, said composition comprising, as an active ingredient, a substance that has an effect of activating TGR5 and shows a high selectivity for TGR5; and a m...  
WO/2021/082683A1
The present invention provides a use of trametinib in preparation of a medicine for preventing and/or treating non-alcoholic hepatitis, and a use of trametinib in preparation of a medicine for preventing and/or treating non-alcoholic fat...  
WO/2021/086271A1
A composition containing mulberry extract comprises of at least a mulberry extract, a sweetener, and an additive; wherein the mulberry extract is obtained from an extraction of leaves or fruits by a solvent, e.g. water or alcohol, or obt...  
WO/2021/084534A1
The present invention provides compositions and methods for treating, ameliorating, preventing and recurrence-preventing anorectal disorders and genital disorders in a mammalian subject. In accordance with various aspects of the present ...  
WO/2021/085540A1
Provided are: a novel fluorine-containing pyrimidine compound with substituents at the 4-position, the 5-position, and the 6-position and a furan ring structure as a substituent at the 2-position; and a manufacturing method by which the ...  
WO/2021/083336A1
A use of the bile acids represented by formula (1) and derivatives thereof in the preparation of a GPR39 agonist, as well as a drug composite which contains such bile acids and the derivatives thereof as the active ingredient, the drug c...  
WO/2021/086610A1
This invention relates to the use of plant extracts, compositions thereof, and compounds isolated from plant extracts or obtained from synthetic means thereof, for the treatment of diseases, disorders or symptoms thereof (e.g., prolifera...  
WO/2021/083372A1
A solid composition containing angiotensin II, a preparation method and use method therefor and a use thereof. The composition comprises angiotensin II and an auxiliary additive, wherein the auxiliary additive comprises sulfobutyl beta c...  
WO/2021/084229A1
A transdermal patch is provided, wherein the patch comprises a cross-linked poly(ethylene oxide) hydrogel loaded with naltrexone, or a pharmaceutically acceptable salt or solvate thereof, and an occlusive adhesive tape. The poly(ethylene...  
WO/2021/083409A1
An anti-CD97 monoclonal antibody, variable region and constant region sequences thereof, and application thereof. The variable region sequences of the anti-CD97 monoclonal antibody comprise nucleotide sequences such as a heavy chain sequ...  
WO/2021/086999A1
Provided herein are compositions and methods to that target microbial proteases to ameliorate the intestinal barrier dysfunction and restore mucosal integrity. They are useful to treat and prevent diseases and disorders caused by pathoge...  
WO/2021/083912A1
The present invention relates to novel uses of nitazoxanide, or analogues thereof.  
WO/2021/082502A1
Provided is a Lactobacillus casei producing short-chain fatty acids in a high yield, a culture method therefor and an application thereof. Lactobacillus casei LC89 capable of producing short-chain fatty acids in a high yield is preserved...  
WO/2021/048195A3
This invention relates to the delivery of a composition, preferably a pharmaceutical composition, comprising D-pinitol, D-Chiro inositol or myo-inositol or any pharmaceutically acceptable salt thereof, for use in the treatment or prevent...  
WO/2021/080257A1
The present invention relates to a composition for preventing or treating inflammatory bowel disease, comprising sulglycotide as an active ingredient. A group to which sulglycotide, an active ingredient of the present invention, was admi...  
WO/2021/080544A1
The invention is related to preparation of a food supplement comprising microorganism mixtures, which is developed scientifically and technologically in order to prevent chronic constipation problems (constipation) in humans, especially ...  
WO/2021/081362A1
The present disclosure relates to a synbiotic compositions, comprising a plurality of preselected strains of probiotic bacteria with a sterilized organic vegetable and fruit juice liquid medium which may be used for colon health and impr...  
WO/2021/079988A1
This agent for promoting odontoblast propagation and differentiation contains a calcium salt of 4-(meth)acryloyloxyethyltrimellitic acid.  
WO/2021/079921A1
Provided are: a growth inhibitor against pathogenic bacteria in the oral cavity and to be added to a composition for the oral cavity; an oral microflora improver; and a composition for the oral cavity using the growth inhibitor and the o...  
WO/2021/079536A1
This composition for lysis of Staphylococcus aureus or this composition for prevention or therapy of diseases caused by Staphylococcus aureus contains as active ingredients: at least one bacteriophage selected from the group consisting o...  
WO/2021/078110A1
Disclosed is a drug combination for preventing or treating irritable bowel syndrome. The drug combination comprises dosmalfate and lysozyme.  
WO/2021/078937A1
The present invention relates to a pharmaceutically compatible iron chelator or prodrug thereof for use in treating and/or preventing a disease caused or aggravated by STAT3 hyperactivity in effector cells in a subject; and to methods, k...  
WO/2021/080020A1
Provided is a novel anti-tumor agent capable of delivering siRNA or shRNA specifically to pancreatic cancer cells and suppressing tumor enlargement, infiltration, and metastasis of pancreatic cancer. The present invention provides a nu...  
WO/2021/078087A1
Disclosed are a traditional Chinese medicine pill realizing targeted release, and a preparation method therefor. The traditional Chinese medicine pill comprises a pill core layer, a middle powder layer and an outer coating powder layer, ...  
WO/2021/077236A1
An onion skin extract with properties that protect the gastrointestinal mucosa against damage induced by non-steroidal anti-inflammatory drugs or by alcohol, pharmaceutical composition or food comprising it, method of obtainment, and use...  
WO/2021/078958A1
The present invention relates to compounds and compositions comprising said compounds, for use in the prevention and/or treatment of non-alcoholic fatty liver disease (NAFLD), in particular hepatic steatosis or non-alcoholic steatohepati...  
WO/2021/078274A1
The present invention relates to a pyridazinone or pyridazine compound and a derivative and a pharmaceutical composition thereof. Specifically, the present invention provides a pyridazinone or pyridazine compound as shown in formula (I) ...  
WO/2021/078912A1
The Applicant has discovered that the peptide of SEQUENCE ID NO: 1 (WKDEAGKPLVK) mediates changes in key biomarker activities associated with NASH (Table 1), and that the peptide is capable of penetrating HepG2 liver cells in a hepatic c...  
WO/2021/078023A1
Provided is a small molecule compound, which is characterized in having the structure represented by the following molecular formula: (I), wherein X1 and X2 are selected from carbon or nitrogen; G1 is a carbocyclic ring or heterocyclic r...  
WO/2021/078864A1
The present invention concerns the field of medications for the treatment of lesions and wounds of the skin and mucosa. The present invention relates to the use of a composition comprising a combination of a mucoadhesive component in the...  
WO/2021/079986A1
A composition for lysing Staphylococcus aureus or a composition for preventing or treating a disease caused by Staphylococcus aureus, said composition comprising, as active ingredients, at least one bacteriophage selected from the group ...  

Matches 1 - 50 out of 95,074