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Matches 1 - 50 out of 35,960

Document Document Title
WO/2021/092358A1
The present inventive concept is related to a modified follicle-stimulating hormone (FSH), in particular, a hypo-glycosylated form of FSH, as well as compositions and formulations including, nucleic acids encoding, cell lines expressing,...  
WO/2021/067941A3
The present disclosure provides, inter alia, compositions, methods, and kits for improving the success rate of in vitro fertilization in small ruminants using microbiome profiles. According to some aspects, the present disclosure provide...  
WO/2021/044357A8
Compositions and devices comprising apomorphine or pharmaceutically acceptable salts are described. The compositions may comprise a solution of apomorphine, or a pharmaceutically acceptable salt thereof, and a propellant. The solution ma...  
WO/2021/088739A1
A method and a device for determining an intestinal probiotic supplement formula, a storage medium, and a processor. The method comprises dividing intestinal probiotics into a plurality of probiotic groups, and dividing each probiotic gr...  
WO/2021/086948A1
Non-hormonal contraception compositions and methods for contraception are provided. One embodiment provides an antibody or an antigen binding fragment thereof that specifically binds to one or more sperm antigens and inhibits the ability...  
WO/2021/081601A1
The present disclosure relates to anti-mullerian hormone (AMH) analogues, more particularly AMH analogues which are agonists of the AMH type II receptor (AMHR2). More particularly, the present disclosure relates to AMH analogues having a...  
WO/2021/085769A1
The present invention relates to a composition comprising Botulinium toxin or a salt thereof for increasing an endometrial blood flow rate, a composition for improving an implantation potential, and a pharmaceutical composition comprisin...  
WO/2021/079339A1
The present invention relates to a stable parenteral dosage form with a ready-to-inject sterile stable aqueous solution of cetrorelix acetate. The invention also relates to an injection device prefilled with the ready-to-inject sterile s...  
WO/2021/080464A1
The invention relates to the field of medicine, and more particularly to reproductive medicine, and can be used in treating women who have had multiple failed in vitro fertilization attempts. The present method involves testing the methy...  
WO/2021/079536A1
This composition for lysis of Staphylococcus aureus or this composition for prevention or therapy of diseases caused by Staphylococcus aureus contains as active ingredients: at least one bacteriophage selected from the group consisting o...  
WO/2021/079986A1
A composition for lysing Staphylococcus aureus or a composition for preventing or treating a disease caused by Staphylococcus aureus, said composition comprising, as active ingredients, at least one bacteriophage selected from the group ...  
WO/2021/079435A1
This composition is for lysing Staphylococcus aureus or treating or preventing diseases caused by Staphylococcus aureus, and contains, as active ingredients, at least one bacteriophage selected from the group consisting of the bacterioph...  
WO/2021/079984A1
The present invention provides a novel compound having an excellent β-lactamase inhibitory effect. The present invention provides: a compound which has an excellent β-lactamase inhibitory effect, and is represented by formula (1a), (1b...  
WO/2021/076618A1
The invention relates to compositions and methods for treating uterine fibroids in vivo, wherein a uterine fibroid treatment agent comprising collagenase in an amount effective to cause shrinkage and/or reduce stiffness of uterine fibroi...  
WO/2021/075491A1
A transdermal absorption-type patch (10) comprises a support body (1) and an adhesive layer (2) layered on the support body (1). The adhesive layer (2) contains: a solid composite body (2a) in which an active ingredient having a molecula...  
WO/2021/076675A1
Embodiments of the disclosure include methods and compositions related to prevention of spontaneous miscarriage in an individual. In certain cases, fibroblasts are provided in an effective amount to an individual in need thereof. Alterna...  
WO/2021/073518A1
Provided in the present invention is the use of an inhibitor of a plasmin inhibitory factor for preventing and/or treating pre-eclampsia or eclampsia, or the use thereof in the preparation of a drug for preventing and/or treating pre-ecl...  
WO/2021/068239A1
Disclosed are a vaginal slow-release administration system for luteal support, a preparation method therefor and a use thereof. The system is a progesterone reservoir type vaginal ring, comprising a core layer, and a film layer double-la...  
WO/2021/070785A1
The discovery has been made that immortalized cells derived from porcine kidney macrophages exhibit a high infection susceptibility for various pig infectious virus strains, which has made it possible to provide, inter alia, a method for...  
WO/2021/069542A1
The present invention concerns compounds and their use in contraception. These compounds are derivatives of zafirlukast and have been found to inhibit CatSper in human sperm cells in low concentrations.  
WO/2021/069700A1
This disclosure relates to crystalline solvated forms of N-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-diox o-1,2,3,4-tetrahydrothieno[2,3- d]pyrimidin-6-yl)phenyl)-N'-methoxyurea. It also relate...  
WO/2021/069711A1
This disclosure relates to crystalline forms, in particular to Form II of N-(4-(l-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6- methoxy-3-pyridazinyl)-2,4-dioxo-l,2,3,4-tetrahydrothieno[2, 3- d ]py rim idin-6-yl)phenyl)-N'-methox...  
WO/2021/064132A1
The invention relates to compositions useful in the treatment of female subjects suffering from menopause related symptoms. There is a strong-felt need for effective treatment and management of such symptoms, which do not rely on estroge...  
WO/2021/063373A1
The present invention relates to a compound represented by formula I and a stereoisomer, tautomer, solvate, polymorph thereof or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, a preparation meth...  
WO/2021/057987A1
The present invention relates to the field of disease test kits, and provides an application of a reagent for measuring the content of calprotectin in faeces (faecal calprotectin) in preparation of a teratozoospermia screening kit. Accor...  
WO/2021/060281A1
The purpose of the present invention is to provide a novel compound which has a prostaglandin E2 (PGE2) receptor EP2/EP4 dual antagonizing effect and is useful as: a preventive or therapeutic agent for a disease selected from cancer, pai...  
WO/2021/052152A1
The present invention relates to the technical field of biomedicine engineering, and provides a composition related to soluble dimer immunoadhesin and a method. The dimeric immunoadhesin comprises a dimerized first and second polypeptide...  
WO/2021/054864A1
The group of inventions relates to medicine, specifically to andrology, and may be used in pharmacology to correct disorders of spermatogenesis. Proposed is the use of 9-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-selenoxanthene to correct disor...  
WO/2021/054865A1
The group of inventions relates to medicine, specifically to pharmacology, and concerns the treatment of fertility disorders in men. Proposed is the use of 9-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-selenoxanthene as an agent for treating pat...  
WO/2021/054866A1
The group of inventions relates to medicine, specifically to sexual pathology, and concerns increasing/restoring sexual desire (libido) and improving sexual function caused by androgen deficiency in males. Proposed is the use of 9-phenyl...  
WO/2021/054863A1
The group of inventions relates to medicine, specifically to andrology. Proposed is the use of 9-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-selenoxanthene as a stimulator of testicular tissue reparative regeneration processes. Also proposed is ...  
WO/2021/050800A1
Provided herein are methods for identifying patient having treatment resistant cancers, such as HPV- related cancers. Therapeutic methods for treatment of cancers are also provided.  
WO/2021/023877A3
The present disclosure provides compositions and methods for treating estrogen-dependent disorders, such as disorders of the female reproductive system, including uterine fibroids and endometriosis, among others. Compounds described here...  
WO/2021/048688A1
The invention is related to medicine, in particular urology, and can be used for creating a product for the treatment of erectile dysfunction. The product contains, as the active ingredient, 5-20 wt % of 9-phenyl-sym-octahydroselenoxanth...  
WO/2021/043726A1
The disclosure provides compositions and methods for the use of oxytocin antagonists, such as substituted pyrrolidin-3-one oxime derivatives of formula (I), among other compounds, in the treatment of subjects undergoing embryo transfer t...  
WO/2021/042911A1
The present invention relates to the field of medicines, and relates to a compound represented by formula (I) and acting as a MAGL inhibitor and a pharmaceutically acceptable salt thereof, a preparation method therefor, use thereof, and ...  
WO/2021/044302A1
The invention relates to the preparation of estetrol of formula (I), derivatives thereof protected at positions 3,15α,16α,17β of general formula (III), and 3-hydroxy derivatives thereof protected at positions 15α,16α,17β of general...  
WO/2021/044357A1
Compositions and devices comprising apomorphine or pharmaceutically acceptable salts are described. The compositions may comprise a solution of apomorphine, or a pharmaceutically acceptable salt thereof, and a propellant. The solution ma...  
WO/2021/039951A1
The present invention addresses the problem of providing a means for improving the diffusibility and dispersibility of an active ingredient in udders, in the case of preparing a formulation of granulocyte-macrophage colony stimulating fa...  
WO/2021/038460A1
The present invention relates to methods of treatment of menstrual cycle induced disorders and symptoms with cathinone, particularly methods employing 3-methyl methcathinone (3-MMC). The present invention also relates to kits comprising ...  
WO/2021/036294A1
A vaginal acid-base buffer gel and a preparation method, the gel consisting of the following components by mass: 1%-39% of an oil phase base, 60%-99% of a water phase base, 0.001%-2% of a pH regulator and 0.05%-5% of a bacteriostat, wher...  
WO/2021/039833A1
The present invention addresses the problem of providing a novel means for preventing the inhibition of the proliferation of keratinocytes even when the keratinocytes begin to contact with each other. The present invention can solve th...  
WO/2021/036803A1
Disclosed is a protein of the amino acid sequence shown in SEQ ID NO:1 or SEQ ID NO:2, and an application of a long-acting protein preparation prepared from a modified protein in the preparation of a drug for improving sexual dysfunction...  
WO/2021/031148A1
Provided are a crystal form of a gonadotropin releasing hormone antagonist, a preparation method therefor, and use thereof. A crystal form C and a crystal form D have high purity, good illumination stability, high temperature stability, ...  
WO/2021/027741A1
Provided are a Lactobacillus johnsonii strain (Ljohn-1) and the use thereof. The strain was deposited in the China Center for Type Culture Collection in June, 2019, with the deposit number CCTCC No. M2019426. The strain, a dominant strai...  
WO/2021/027742A1
Provided is a Lactobacillus crispatus Lcris-2, which was preserved in the China Center for Type Culture Collection in June 2019 with the preservation number: CCTCC No. M2019427. The strain belongs to the dominant strain of women's vagina...  
WO/2021/027740A1
A multi-lactobacillus composition. The multi-lactobacillus composition is a dominant strain separated and selected from the vagina of a healthy woman in China. The multi-lactobacillus composition comprises at least three of the following...  
WO/2021/027937A1
The present invention relates to new solid forms (including crystalline and amorphous solids) of relugolix, a compound applied as gonadotropin-releasing hormone (GnRH) receptor antagonist, and a preparation method therefor. The provided ...  
WO/2021/030655A1
This document relates to methods and materials for assessing and/or treating hypertensive disorders of pregnancy (e.g., preeclampsia) and/or one or more comorbidities associated with a hypertensive disorder of pregnancy. For example, met...  
WO/2021/023805A1
The present invention relates to a compound for treatment of a disease or disorder involving depression, erectile dysfunction, anxiety, sexual dysfunction and/or ejaculatory disorders; or a combination thereof.  

Matches 1 - 50 out of 35,960