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WO/2018/207847A1 |
The present invention provides: a pyrazole-3-carboxylic acid amide derivative having an excellent pest control effect or a salt thereof; and a pest control agent which contains this pyrazole-3-carboxylic acid amide derivative as an activ...
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WO/2018/202524A1 |
The invention relates to compounds of formula (I), wherein Z, Y, A1, A2, A3, A4, X, R7, R8 and R9 have the above-mentioned meanings, and to methods and intermediate products for the production and use thereof for controlling animal pests...
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WO/2018/204563A1 |
The present invention relates to the field of malaria. More specifically, the present invention provides compositions and methods useful for the prophylaxis and treatment of malaria, as well as other parasitic and fungal infections. In a...
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WO/2018/202897A1 |
The invention relates to various compositions, including pharmaceutical compositions comprising an oxidation agent selected from sodium, potassium, magnesium or calcium hypochlorite, chlorite or chlorate, an artemisinin composition or a ...
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WO/2018/201196A1 |
A composition or medicament including an extract of Terminalia ferdinadiana (T. ferdinandiana) as an antimicrobial or antibacterial agent for use in treating microbiasl/bacterial infection in humans or animals, preferably B. anthracis or...
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WO/2018/199208A1 |
The present invention addresses the problem of developing and providing a novel insecticide for agriculture and horticulture in response to the occurrence of pests resistant to existing chemicals, etc., since there is still large damage ...
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WO/2018/198021A1 |
The present invention relates to dosing regimen of a new antimalarial drug, as monotherapy or combination therapy.
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WO/2018/200812A1 |
Provided herein are immunoconjugates comprising STING agonists. Also disclosed are methods of making the immunoconjugates and methods of treating cancer using the immunoconjugates.
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WO/2018/193063A2 |
The present invention provides a fragment of piasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of piasmodium cir...
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WO/2018/189490A1 |
The invention relates to microcapsules intended to protect probiotics, comprising a shell and a core wherein the probiotics are dispersed in the form of biofilms distributed in distinct clusters, characterised in that the shell and the c...
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WO/2018/189314A1 |
The present invention relates to an injectable implant comprising an effective amount of a macrocyclic lactone, or a salt thereof, and a bioresorbable polymer, and its use in preventing and/or treating parasites infestations in non human...
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WO/2018/190321A1 |
A compound represented by formula (1), or a salt thereof, is provided that is effective as a parasitic pest control agent. In the formula, R1 represents an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group, etc., R2 repre...
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WO/2018/185685A1 |
The present invention relates to a topical pharmaceutical composition comprising: at least two pharmaceutical agents selected from the group consisting of pentamidine isethionate, ketoconazole and miltefosine; an agent for boosting skin ...
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WO/2018/187623A1 |
The present invention provides crystalline forms of compound of formula (la) and processes of making the crystalline forms. Also provided are compositions comprising the crystalline forms and crystalline forms for treating or preventing ...
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WO/2018/185346A1 |
The invention relates to a pharmaceutical composition for systemic, particularly parenteral treatment of infectious diseases, based on an aqueous, sterile and pyrogen-free solution of chlorine dioxide, which contains 5 to 1000 mg/l (ppm)...
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WO/2018/182523A1 |
The present invention relates to a vaccine for therapeutic or prophylactic treatment of a pathological condition. In particular, the present invention relates to a vaccine for therapeutic or prophylactic treatment of malaria. In an aspec...
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WO/2018/176079A1 |
This invention relates to berberine alkaloids, formulations thereof and their use for the prevention and/or treatment of infectious disease, especially disease caused by C. perfringens and Eimeria in animals. The invention also relates t...
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WO/2018/183922A1 |
The present invention provides methods and compositions for immunizing a subject against malaria.
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WO/2018/176093A1 |
This invention relates to berberine alkaloids, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals, particularly Lawsonia infection. In particular, the invention relates to berberine al...
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WO/2018/183512A1 |
A single-dose oral formulation of spinosad and lufenuron and methods for its use in the extended control of a flea infestation on a domestic animal such as a dog without emesis.
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WO/2018/178345A1 |
The present invention is directed to a salt of a compound of formula (I), R1 is halogen or methyl; X is methyl, OR2, or SR2; Y1, Y2 is CR3 or N, and one of Y1, Y2 is N and one of Y1, Y2 is CR3; R2 is methyl or ethyl; R3 is hydrogen or me...
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WO/2018/175633A1 |
Provided herein are methods and compositions for vaccinating subjects against malaria, or otherwise promoting the development of an immune response against Plasmodium falciparum. In some aspects, provided here are compositions comprising...
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WO/2018/174170A1 |
A compound represented by formula (I) has an excellent controlling effect on arthropod pests. (In the formula, Q represents a group represented by formula Q1 or the like; A1 represents CR7 or the like; A2 represents NR8A or the like; A4 ...
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WO/2018/167271A1 |
The present invention is related to a stable topical veterinary composition comprising:• a) selamectin, • b) dimethyl sulfoxide (DMSO) in an amount between 0.5-15% w/v,• c) an organic solvent and • d) optionally an antioxidant.
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WO/2018/167385A1 |
The present invention relates to a composition comprising pyrethrum for the control of target arthropod pests on a human or animal to be treated. The composition comprises a synergic mixture as an active agent, consisting of pyrethrum, a...
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WO/2018/166427A1 |
Provided are a Streptomyces avermitilis strain C63-51 with a high yield of ivermectin B1b and a method for producing ivermectin B1b by using this strain. By using the above-mentioned strain and method, efficient production of single iver...
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WO/2018/161291A1 |
Provided in the present invention is an eprinomectin nanoemulsion, the eprinomectin nanoemulsion containing eprinomectin, a solvent and a long-chain monoester; the monoester is represented by the formula R-COO-R', wherein R is selected f...
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WO/2018/161938A1 |
A gynecological vaginal wash for adjusting female vaginal microecology and a preparation method thereof. The wash is prepared by adding a natural fragrance to acidic water with an acidic water volume concentration of 0.01-0.5% and adjust...
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WO/2018/162312A1 |
The present invention relates to novel spiro compounds of formula I, wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their ...
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WO/2018/160845A1 |
This application describes compounds, compositions, and methods which are useful in treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite.
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WO/2018/157874A1 |
Disclosed are a dihydroartemisinin diploid derivative, a pharmaceutical composition thereof, and an application. The derivative is an artemisinin diploid, used for drugs treating or preventing malaria caused by plasmodium, drugs treating...
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WO/2018/153957A1 |
The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.
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WO/2018/157083A1 |
Plasmodium P47 D2 polypeptides, products, compositions and kits containing such polypeptides and methods (processes) of making and using such polypeptides in analytical, research, diagnostic and human and animal health applications. Also...
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WO/2018/152602A1 |
The present invention relates, in general, to a combination of Crotamine and drugs used for therapy. More specifically, the present invention relates to a combination of Crotamine, a toxin from the snake Crotalus durissus terrificus, and...
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WO/2018/149909A1 |
The present invention relates to pharmaceutical compositions for the treatment of helminthiasis, which comprise the active ingredient felodipine or a pharmaceutically suitable salt or solvate thereof. The invention relates in particular ...
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WO/2018/148186A1 |
Provided herein are immunogenic compositions containing recombinant proteins capable of presenting all, or antigenic portions of, the Eimeria tenella Elongation Factor 1 alpha, or EF-1α, protein in the development of active immunity to,...
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WO/2018/148660A1 |
Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The ...
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WO/2018/141063A1 |
Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one em...
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WO/2018/141029A1 |
The present invention relates to immunogenic polypeptides, immunogenic fragments thereof and compositions comprising same, for use in eliciting an immune response in a subject to a tick. The invention also provides for methods of using s...
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WO/2018/142288A1 |
The invention relates to compounds and pharmaceutical compositions for use in treating malaria infections. The invention also relates to uses and methods of treating a malaria infection in a subject using the compounds and pharmaceutical...
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WO/2018/139436A1 |
The present invention provides: a heterocyclic compound which exhibits an excellent controlling effect against harmful arthropods and which is represented by formula (I) (in the formula, Q denotes a group represented by Q1 or the like, A...
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WO/2018/140533A1 |
Compositions are provided that contain sporulated coccidial oocysts, wherein the compositions are free of antibiotics and comprise formalin at a concentration sufficient to inhibit microbial growth for at least 12 months while maintainin...
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WO/2018/132882A1 |
The present invention pertains to the field of the production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the invention describes the production of the re...
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WO/2018/129618A1 |
The present disclosure relates to compounds of Formula (I) which are multimeric forms of a monomeric binding peptide linearly bonded to PEG moieties to form the multimers. The multimeric forms stimulate angiogenesis and promote wound hea...
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WO/2018/130853A1 |
The present invention relates to novel compounds and pharmaceutically acceptable salts or solvates thereof which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such...
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WO/2018/124129A1 |
The present invention addresses the problem of developing and providing a novel agricultural and horticultural insecticide due to factors such as the development of pests resistant to existing chemicals since damage by pests is still a m...
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WO/2018/124088A1 |
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...
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WO/2018/124181A1 |
The present invention provides a functionalized mRNA including mRNA and double-stranded RNA including at least one RNA oligomer hybridized with mRNA. Functionalized mRNA is provided according to this configuration.
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WO/2018/124896A1 |
The subject of the invention is a composition for prevention and control of bee diseases and the use of the hemp oil for preparation of the composition. In more detail, the invention relates to a composition comprising hemp essential oil...
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WO/2018/115532A1 |
The invention relates to a composition comprising at least one compound of formula I R-SOa-S-R' (I), in which a is equal to 1 or 2 and R and R' are, independently of one another, a linear or branched C1-C5 alkyl group, for use in the pre...
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