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WO/2023/094817A1 |
According to the invention, there is provided a solid, amorphous mono-particulate powder composition comprising a pharmacologically-effective dosage amount of atropine, or a pharmaceutically-acceptable salt thereof, encapsulated in an am...
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WO/2023/095568A1 |
[Problem] To provide a method for producing hydroxytyrosol from olive leaves, and a hydroxytyrosol-containing composition. [Solution] This method for producing hydroxytyrosol from olive leaves includes a step for pressurized hot water ex...
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WO/2023/088290A1 |
A composition containing Bifidobacterium lactis and human milk oligosaccharides and an application thereof. The composition is a composition containing Bifidobacterium lactis and human milk oligosaccharides (HMOs for short). The composit...
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WO/2023/087065A1 |
The present invention relates to methods, as well as compositions and kits therefor, for preventing or reducing drug-induced cardiotoxicity in subjects caused by cardiotoxic agents, the method comprising administering to the subject an e...
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WO/2023/092134A1 |
Methods are disclosed herein for promoting survival of a donor liver in a recipient subject, wherein the donor liver is homozygous for rs738409:G mutation in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene. The m...
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WO/2023/088073A1 |
The present invention relates to a multifunctional American ginseng hydrolyzed peptide, a preparation method therefor, and an application thereof. The content of active peptide in the American ginseng hydrolyzed peptide provided by the p...
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WO/2023/086409A1 |
Patients experiencing cardiac arrest may be treated using an extracorporeal membrane oxygenation (ECMO) device to rapidly restore blood circulation and provide oxygenated blood to vital organs. However, ECMO is known to lead to tissue da...
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WO/2023/082217A1 |
A protective agent containing a nano-selenium Cordyceps militaris aqueous extract, and a use of the nano-selenium Cordyceps militaris aqueous extract in reducing radiotherapy injury. The nano-selenium Cordyceps militaris aqueous extract ...
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WO/2023/082216A1 |
An ultra-small selenium nanoparticle-loaded metal-organic framework composite, and a preparation method therefor and an application thereof. The method comprises: adding PEG 400 and selenium powder into a beaker, and stirring after sonic...
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WO/2023/081873A1 |
The present invention provides materials and methods for alleviating organophosphate toxicity. More specifically, the invention provides pharmaceutical compositions comprising a protein, and/or biologically-active fragments and variants ...
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WO/2023/081785A1 |
Methods and compositions for assessing the susceptibility of a subject to chemotherapy-induced neuropathy (CIPN) comprising obtaining one or more measurement of the GSH recycling dependent antioxidant activity of the subject's red blood ...
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WO/2023/081157A1 |
A method including administering a therapeutically effective amount of a therapeutic agent to a subject for improving exercise performance, treating obesity, fatty liver, rhabdomyolysis, Leigh syndrome, mitochondrial Complex I deficiency...
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WO/2023/081784A1 |
Methods and compositions for assessing the susceptibility of a subject to chemotherapy-induced neuropathy (CIPN) comprising obtaining one or more measurement of the GSH recycling dependent antioxidant activity of the subject's red blood ...
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WO/2023/072434A1 |
The invention relates to new spermine derivatives of Formula (I), wherein the meaning of the groups R1, R2, n and m is defined in the description, to a pharmaceutical composition thereof and to their use as heparin antidotes in the contr...
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WO/2023/077016A1 |
Provided herein are methods and compositions for prevention of, reduction of risk of, amelioration of, and/or treatment of neurological disorders related to synaptopathies through manipulation of SIRPα and/or CD47.
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WO/2023/068362A1 |
Disclosed are: a mammalian cell modification method comprising a step for preparing nanoparticles each based on a copolymer that includes a polymer chain segment having a poly(ethylene glycol) segment and a cyclic nitroxide serves as a p...
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WO/2023/068193A1 |
The present invention addresses the problem of providing a detoxifying agent and a detoxifying agent kit both for detoxifying CO and HCN in a living body simultaneously. Provided is a detoxifying agent for removing carbon monoxide and ...
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WO/2023/065833A1 |
An oxygen capsulate, a preparation method therefor comprising the following steps: carrying out three-stage separation on deodorized cocoa butter, then carrying out mixing treatment on negative oxygen ions and deodorized cocoa butter liq...
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WO/2023/067141A1 |
The present invention relates to an antioxidative preparation for technical formulations, and to a production method. The preparation contains a mixture of plant extracts from various plant-based raw materials and/or residual materials, ...
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WO/2023/060320A1 |
The present disclosure generally relates to transdermal formulations comprising one or more chloride intracellular channel (CLIC) proteins, processes for preparing the transdermal formulations, and applications for the transdermal formul...
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WO/2023/034447A9 |
Compounds for binding carbon monoxide are provided (e.g., to sequest carbon monoxide in a composition). Compounds according to certain embodiments include water soluble metal porphyrin complexes having substituents that provide for water...
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WO/2023/062640A1 |
The present invention provides a solvent-free, non-GMO oleoresin obtained from Blakeslea trispora, comprising phytoene at a concentration of 10-40% (w/w). In addition, the invention is directed to compositions and to topical and oral dos...
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WO/2023/064880A1 |
The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.
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WO/2023/056917A1 |
Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nuc...
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WO/2023/060094A1 |
Provided herein are compositions and methods of modulating an aversive taste of active pharmaceutical ingredients (API) in a medicament, nutrient, and/or a dietary supplement via inhibition of a purinergic receptor. Additionally provided...
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WO/2023/056980A1 |
Provided are design of self-replicating RNA molecules and an application thereof, the self-replicating RNA molecules each comprising: a first RNA sequence, which encodes an N protein or a functional fragment thereof; a second RNA sequenc...
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WO/2023/052520A1 |
The present invention relates to a condensation product, obtained or obtainable by reaction of phenol, formaldehyde, sulfuric acid and urea, for use in a method for the treatment or prevention of a condition associated with one or more p...
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WO/2023/051925A1 |
The present invention relates to a condensation product, obtained by the reaction of a phenolic compound and a carbonyl compound, for use in a method for the treatment or prevention of a condition associated with one or more protease(s) ...
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WO/2023/050585A1 |
A medical hydrogen storage material and a preparation method therefor, which are applicable to the field of biomedical applications. The medical hydrogen storage material comprises a high-molecular polymer containing an alcoholic hydroxy...
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WO/2023/054168A1 |
Provided is a water-in-oil composition for external use that contains ascorbic acid or a salt thereof. This prepared water-in-oil composition for external use contains: (A) at least one selected from the group consisting of ascorbic acid...
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WO/2023/052573A1 |
Nicotinamide riboside trioleates chloride (NRTOCl) is a novel hydrophobic derivative of nicotinamide riboside chloride. It can be used in a composition formulated for oral administration, preferably a beverage, such as a Ready-to-Drink (...
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WO/2023/047708A1 |
An anti-aging agent that includes K11H[(VO)3(SbW9O33)2] and/or Na9[SbW9O33].
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WO/2023/048216A1 |
The purpose of the present invention is to provide high-purity crystals of anserine and a method for producing the crystals. The purpose is accomplished with, for example, crystals of anserine which give, in an examination with character...
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WO/2023/048096A1 |
The present invention provides a Grifola albicans featuring caps that are not easily colored, and a method for cultivating same. Specifically, provided is a Grifola albicans variety having an accession number of NITE BP-03509, and a prog...
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WO/2023/040084A1 |
A method for extracting collagen tripeptide, a collagen tripeptide prepared using said method, and an application thereof in preparing an antioxidant product. The preparation method comprises: crushing fish skin, then washing the fish sk...
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WO/2023/040077A1 |
Disclosed in the present invention are a fermented Ophiocordyceps sinensis powder with high adenosine and high ergosterol, and a production method therefor, which relate to the technical field of fermented Ophiocordyceps sinensis powders...
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WO/2023/043173A1 |
The present invention relates to an antibacterial and antioxidant composition containing a grape callus culture medium, as an active ingredient, comprising epsilon (ε)-viniferin, delta (δ)-viniferin, resveratrol, and the like, and, spe...
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WO/2023/040097A1 |
Provided is a method for extracting a flavonoid component in millettia speciosa champ, comprising the following steps: performing quick-freezing treatment on millettia speciosa champ; preparing a eutectic solvent-ethanol aqueous two-phas...
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WO/2023/035632A1 |
The present disclosure relates to the field of skin repair and improvement, and in particular to an active peptide and a use thereof. The active peptide obtained in the present disclosure has the advantages of delaying senescence, anti-o...
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WO/2023/038418A1 |
The present invention relates to a bifidobacterium bifidum EPS DA-LAIM strain (KCTC 14638BP) for intestinal health, having the effect of promoting growth of lactobacillus, polysaccharides produced from same, and a composition comprising ...
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WO/2023/038624A1 |
Methods, compositions, and systems for steeping, propagation and fermentation, particularly large-scale operations for production of starch and ethanol and fermentation product streams are provided. Addition of mycotoxin mitigating enzym...
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WO/2023/038162A1 |
The present invention relates to a composition for improving oxidative stress comprising a membrane-free stem cell extract, wherein a membrane-free stem cell extract derived from adipose stem cells is used at a concentration of 0.5 to 2....
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WO/2023/036219A1 |
Provided in the present invention are a homogalacturonan, a complex, and a preparation method therefor and the use thereof. Provided in the present invention is a preparation method for homogalacturonan, comprising the following steps: s...
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WO/2023/034615A1 |
Disclosed are methods for treatment of neurodegenerative diseases or inhibiting the progression of neurodegenerative disease. The methods may comprise inhibiting cellular dysfunctionality and subsequent cell death due to cellular accumul...
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WO/2023/029928A1 |
An amino lipid and an application thereof: using ethenesulfonyl fluoride (ESF), a dual-function electrophile, to build an amine head group and a hydrophobic chain into an amino lipid, fully utilizing the click chemical reaction propertie...
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WO/2023/028730A1 |
Disclosed is the use of aloesone in the preparation of a product for resisting oxidative stress injury. The aloesone has anti-oxidation activity of directly scavenging DPPH free radicals, and can scavenge ROS to inhibit macrophage apopto...
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WO/2023/030272A1 |
An isolated antigen binding protein, the antigen binding protein binding the protein G protein-coupled receptor, class C, group 5, member D (GPRC5D) at an EC50 value of 1.0 μg/mL. A chimeric antigen receptor comprising the antigen bindi...
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WO/2023/025258A1 |
The present disclosure provides a composition and method used for controlling heat generation in an organism, and a use. The composition of the present disclosure comprises a molecule used for modulating a combination of EBI-3 and p28, o...
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WO/2023/026043A1 |
The present invention relates to nutritional compositions for maintaining and enhancing one carbon (1C) metabolism. The compositions are useful for maintaining general body health, reducing physiological consequences of metabolic stress,...
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WO/2023/027164A1 |
The present invention addresses the problem of providing an ROS production promoter. The present invention provides an ROS production promoter that contains an agent that recognizes a transferrin receptor.
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