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Matches 1 - 50 out of 5,711

Document Document Title
WO/2023/164848A1
Provided are a catalyst loaded with a TEMPO compound, and a preparation method therefor and the use thereof. The catalyst loaded with a TEMPO compound uses a polymer resin as a carrier, wherein the polymer resin is a polystyrene resin co...  
WO/2023/165094A1
Disclosed in the present application are a hydroxypentyl benzoic acid diester compound, and a preparation method therefor and the use thereof. The principle of combination is used in the present application. On the one hand, the drug con...  
WO/2023/161765A1
Disclosed is a system (100), a process (300), and a process (400) for washing of slurry mixture of mono nitroxylene and recovery of ammonia and water from slurry mixture of mono nitroxylene. Further, the said system (100) comprises of pl...  
WO/2023/156832A1
Disclosed in a process (100) for preparation of highly pure 4-(N-butyl) aniline by performing steps of adding (101) sulfuric acid and a n-butylbenzene to a tank reactor, nitration (103) of n-Butylbenzene by using a nitrating agent, where...  
WO/2023/157862A1
Provided is a method for producing α-fluoroether starting from an inactivated chloride. Disclosed is a method for producing a compound represented by formula (3), the method comprising step A in which a compound represented by formula (...  
WO/2023/140012A1
A compound according to one embodiment of the present disclosure is represented by formula (1). In formula (1), R1 to R22 each independently include at least one atomic element selected from the group consisting of H, B, C, N, O, F, Si...  
WO/2023/120292A1
Provided is a method for producing a sulfonamide derivative, the method being characterized by including a step of causing a compound having a nitro group to react with a compound having a thiol group under light irradiation, and forming...  
WO/2023/092208A1
The present invention relates to a method for producing a twice photocrosslinkable injectable polymeric solution, capable of gelling in situ in physiological conditions and under visible light, and releasing nitric oxide (NO) in a prolon...  
WO/2023/072285A1
Disclosed are an enoate compound containing an aromatic ring, and a preparation therefor and the use thereof. The compound of the present invention is simple in terms of structure and easy to synthesize. Synthetic raw materials are deriv...  
WO/2023/070961A1
Provided is a method for a photooxidation reaction of a benzylic carbon-hydrogen bond of an aromatic compound under acid/photocatalytic conditions. The use of the method is to synthesize aryl formic acids and aryl ethyl ketones. The acid...  
WO/2023/057545A1
A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in a method of therapy, wherein: R1 is selected from: (i) phenyl, optionally substituted by R1a and R1b; (ii) pyridyl; and (iii) naphthyl, optionally subst...  
WO/2023/048034A1
The present invention addresses the problem of providing a method for producing an aromatic compound having an ethynyl group by means of a simple and inexpensive coupling reaction using a halogen-containing aromatic compound. The prese...  
WO/2023/043197A1
The present invention provides a cannabidiol derivative, a method for preparing same, and a composition for cognitive function improvement comprising same. The novel cannabidiol derivative of the present invention has been confirmed to e...  
WO/2023/041781A1
A chemical process for preparing at least one aromatic isocyanate, said process comprising n chemical sub-processes sp(i), wherein a sub-process sp(i) is carried out in a chemical processing sub-unit U(i), i=1...n, n≥1, wherein during ...  
WO/2023/040100A1
The present invention belongs to the technical field of organic synthesis, and provides a method for preparing 3-hydroxy-4-nitrobenzaldehyde. In the present invention, dimethyl sulfoxide is used as a solvent for a reaction; and since dim...  
WO/2023/036720A1
The present invention relates to a compound of structure (I), wherein A is a core moiety which is selected from structure (Ia), (Ib), (Ic) and (Id), to which is attached through X, a direct valence bond or a divalent linking group, m num...  
WO/2023/023201A1
The present invention relates to precious metal (Pd/Pt/Rh/Ru) free, preferably Pd free, processes for preparing a compound having formula (1) wherein: R1, R2, and X are as defined in the specification, or a salt thereof. Preferably, the ...  
WO/2023/018473A1
The present invention relates to the analytical methods for determining the concentration of the analyte in the sample and one or both of (i) the absolute configuration of the analyte in the sample, and (ii) the enantiomeric and/or the d...  
WO/2023/008401A1
The present invention addresses the problem of industrially and inexpensively providing an aromatic compound having an ethynyl group using Sonogashira coupling, with chloronitrobenzene, the raw materials of which are inexpensive, being u...  
WO/2023/004687A1
Provided by the present invention is an unnatural amino acid, which is a compound having a structure as shown in formula (I) or an enantiomer thereof. Further provided by the present invention is an application of the unnatural amino aci...  
WO/2022/266940A1
A nitrification device for mesitylene production, comprising a device housing. A motor is fixedly mounted in the middle of the top of the device housing; a nitrated compound inlet and a mixed acid inlet are respectively formed in the top...  
WO/2022/263620A1
The present invention relates to a method for preparing a compound suitable for signal enhanced magnetic resonance imaging comprising the steps of vinylating a mono-, di- or tricarboxylic acid comprising a moiety -Q-Z with Q being O or N...  
WO/2022/253354A1
The present invention provides a method for preparing aldehydes or ketones by oxidizing alcohol. Alcohol is oxidized into an aldehyde or ketone by using water as a solvent, using hydrated ferric nitrate (Fe(NO3)39H2O), 4-hydroxy-2,2,6,6-...  
WO/2022/254047A1
The invention generally relates to emodin derivatives of general structure (I), to pharmaceutical compositions comprising same and to their uses in medicine, especially in the treatment of bacterial or viral infections. The invention fur...  
WO/2022/243099A1
A process for preparing substituted biphenyls of the formula (I) which comprises reacting a compound of the formula (Il) in the presence of a base and of a palladium catalyst, with an organoboron compound of the formula (IV).  
WO/2022/232366A1
Described herein are novel reduction reactions. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticide...  
WO/2022/223390A1
The present invention relates to a method of synthesizing a photolytically degradable compound, which method comprises identifying a biologically active target molecule comprising substituted aromatic group(s); providing a starting mater...  
WO/2022/219953A1
The purpose of the present invention is to provide: an ion exchanger which shows small shrinkage upon the contact with an organic solvent in a water-wetted state; and a method for producing the ion exchanger. Provided is an ion exchanger...  
WO/2022/150721A9
The present disclosure provides a class of compounds including a ligand moiety that specifically binds to a cell surface receptor, such as a folate receptor. The cell surface folate binding compound can trigger the receptor to internaliz...  
WO/2022/205574A1
The present invention relates to a method for producing entacapone tablets, comprising: auxiliary material sieving, batching, mixing, sieving, mixing, dry granulation, sieving, mixing with magnesium stearate, and pressing into a tablet f...  
WO/2022/204381A1
Disclosed herein are new pharmacological therapies that increase CYB5R3 activity, improve vascular function and limit inflammation by restoring the redox balance in CVD. In one embodiment, disclosed herein are compounds that include an a...  
WO/2022/201155A1
The present invention relates to a novel nitration process of 2- chloro -4- fluorobenzoic acid to 2-chloro-4- fluoro-5-nitrobenzoic acid, 2-chloro-4- f luoro-3 -nitrobenzoic acid and 3, 5-dinitro-2-chloro-4- fluorobenzoic acid; purifying...  
WO/2022/192414A2
Provided herein are synthetic methods for the preparation of intermediates that are utilized in the synthesis of omecamtiv mecarbil dihydrochloride.  
WO/2022/186162A1
The purpose of the present invention is to provide a method for producing a nucleophilic reaction product, the method being capable of using a halogenated carbonyl compound for the reaction without requiring isolation thereof, while bein...  
WO/2022/171808A1
The present invention relates to a Photo-caged MALDI Matrix Compound for use in a method of matrix-assisted laser desorption/ionization mass spectrometry, as well as to a sprayable liquid composition and a Photo-sensitive MALDI Matrix Co...  
WO/2022/168670A1
The purpose of the present invention is to provide a charge transfer complex which enables the achievement of a curable resin composition that has an excellent balance between curability and storage stability if used as an epoxy resin cu...  
WO/2022/155936A1
Disclosed in the present invention is a method for synthesizing an aryl benzyl ether compound, i.e., synthesizing a corresponding aryl benzyl ether compound by means of an oxidative coupling reaction of a phenolic compound and a toluene ...  
WO/2022/155932A1
Disclosed is an application of an iron (III) complex containing 1,3-di-tert-butyl imidazolium cation in synthesizing arylbenzyl ether compounds. Specifically, di-tert-butyl peroxide is used as an oxidant, and a corresponding arylbenzyl e...  
WO/2022/140654A1
The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts thereof.  
WO/2022/134297A1
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...  
WO/2022/127038A1
Disclosed herein is a method for producing dinitronaphthalene, which includes subjecting naphthalene to a nitration reaction with nitric acid in a reactor, so as to obtain a dinitronaphthalene-containing solution. The reactor includes at...  
WO/2022/121317A1
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...  
WO/2022/108984A1
The invention relates in particular to methods and intermediates for the synthesis of Compound 1 that inhibits MCL1 and is useful in the treatment of cancers.  
WO/2022/100487A1
Disclosed is an amino-combretastatin derivative, and in particular a compound represented by general formula (I), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a hydrate of the pharmaceutically acceptable salt thereof...  
WO/2022/098847A1
Disclosed herein are compounds related to tolcapone and its metabolite, 3-OMT, along with 3-deoxytolcapone, as well as pharmaceutical compositions comprising the same. Also disclosed are methods of using such compounds and compositions, ...  
WO/2022/083728A1
Disclosed are an intermediate of pregabalin and a preparation method therefor. Provided are a compound as represented by formula (I) and a preparation method therefor. The preparation method for the compound as represented by formula (I)...  
WO/2022/082148A1
Processes and systems for producing isomeric mixtures of aromatic amine monomers from aromatic feeds. An example process for producing isomeric mixtures of aromatic amine monomers from aromatic feeds may include nitrating at least a port...  
WO/2022/068057A1
Provided is a continuous production method for 2,4-dinitrochlorobenzene. In the method, concentrated nitric acid, concentrated sulfuric acid, and chlorobenzene serve as raw materials; after a mixed acid solution is prepared, chlorobenzen...  
WO/2022/061920A1
A method for preparing 3',5'-dichloro-2,2,2-trifluoroacetophenone. The method comprises subjecting 3'-chloro-2,2,2-trifluoroacetophenone as a raw material to four steps, i.e. nitrification, reduction, chlorination and deamination, so as ...  
WO/2022/052683A1
The present invention provides a method for preparing a water-soluble magnolol derivative and a honokiol derivative, methods for preparing intermediates of a water-soluble magnolol derivative and a honokiol derivative, and a related mono...  

Matches 1 - 50 out of 5,711