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WO/2017/046695A1 |
The present invention provides a process for preparation of trientine dihydrochloride (1) comprising reaction of protected triethylene tetramine with hydrochloric acid in an aqueous system to yield the dihydrochloride salt wherein the fo...
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WO/2017/046709A1 |
The invention provides a method of preparing a biocide. The method includes forming a reaction mixture of a first compound and a second compound. The first compound is a quaternary ammonium salt providing a desired cation and in the form...
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WO/2017/036357A1 |
Provided are a cathepsin K inhibitor and application thereof, and specifically is a compound having a structure represented by formula (I) and being used to treat or prevent a cathepsin dependent disease. In particular, the cathepsin is ...
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WO/2017/005907A1 |
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.
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WO/2017/005908A1 |
The invention relates to zeolitic adsorbents based on agglomerated crystals of zeolite X comprising barium, potassium and sodium. These adsorbents are applicable in the separation of fractions of aromatic C8 isomers, especially xylenes.
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WO/2017/000270A1 |
The present invention relates to a crystal form A and a crystal form B of sertraline citrate, and preparation methods therefor. The crystal form A and the crystal form B of sertraline citrate have good dissolvability, high dissolution an...
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WO/2016/209628A1 |
This disclosure describes a low temperature process for the preparation of tertiary amines from nitriles and secondary amines via reductive amination using transfer hydrogenation. The process can use a nitrile and a dialkylamine and proc...
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WO/2016/209629A1 |
This disclosure describes a low temperature process for the preparation of dimethyl amines from nitriles via reductive amination. In some embodiments, the process proceeds under mild conditions with aqeuous dimethylamine and show an unex...
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WO/2016/199763A1 |
The present invention pertains to a method for producing 1-cyclopropylethylamine or an acid addition salt thereof. Provided is a method for producing high-purity 1-cyclopropylethylamine or an acid addition salt thereof including reacting...
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WO/2016/194727A1 |
The present invention manufactures an age resistor using a method with excellent industrial productivity while using biomass as starting material. The invention is characterized in comprising a step for forming acetone by oxidizing isopr...
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WO/2016/193882A1 |
The present invention provides one pot process for preparation of highly pure unsaturated cinacalcet hydrochloride (II) comprising: i) converting 3-(trifluromethyl) cinnamic acid (III) into 3-(3-(trifluoromethyl)phenyl)prop-2-en-1-ol (IV...
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WO/2016/196816A1 |
The invention generally relates to methods of making substituted arenes via direct C-H amination. More specifically, methods of making para- and ortho-substituted arenes via direct C-H amination are disclosed. This abstract is intended a...
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WO/2016/191873A1 |
A compound having a chemical formula according to Formula (I) is disclosed where one of Z1, Z2 and Z3 is and one of the Z1, Z2, and Z3 that is bonded to a carbon atom that is adjacent to the carbon atom bonded to is P(AR1)(A'R2). Metal-b...
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WO/2016/189129A1 |
The invention relates to a method for the reductive amination of a carbonyl compound, comprising one or more carbonyl groups that can be aminated reductively, forming the corresponding primary amine, characterized in that the reaction is...
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WO/2016/183101A1 |
Methods for synthesizing trifluoroethyl, difluoroethyl, pentafluoropropyl, and difluorophenethyl anilines by palladium-catalyzed coupling of fluoroalkylamines with aryl bromides and aryl chlorides are provided herein. The reaction is con...
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WO/2016/182257A1 |
Provided is a method for purifying 1,4-diaminobutane, comprising the steps of: separating a second composition containing 1,4-diaminobutane carbonate from a first composition containing 1,4-diaminobutane carbonate by distillation; and re...
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WO/2016/177656A1 |
The instant invention relates to novel solid forms of the compound of formula (I) or salts thereof (formula I) as well as processes for their manufacture, pharmaceutical compositions comprising them, and their use as medicaments.
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WO/2016/172128A1 |
Provided is a method for preparing a structure directing agent (SDA) for crystalline molecular sieve synthesis comprising the steps of (a) hydrolyzing analkyl sulfate counterion of a quaternary ammonium salt to produce an organic ammoniu...
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WO/2016/167361A1 |
The purpose of the present invention is to provide a novel method for producing an organic compound substantially free of Pd in an inexpensive and simple manner. The present invention pertains to a method for producing an organic compoun...
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WO/2016/164767A1 |
The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.
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WO/2016/160857A1 |
The present invention provides an N-substituted glycinium (fluorosulfonyl)(trifluoro- methylsulfonyl)imide compounds and methods for producing and using the same. In particular, the N-substituted glycinium (fluorosulfonyl)(trifluoromethy...
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WO/2016/160855A1 |
The present invention provides N-substituted glycinium bis(fluorosulfonyl)imide compounds and methods for producing and using the same. In particular, the N-substituted glycinium bis(fluorosulfonyl)imide compound is of the formula: (I) w...
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WO/2016/155948A1 |
Process for preparing aminated aromatic hydrocarbons that may be substituted comprising the steps of reacting an aromatic hydrocarbon with ammonia in the presence of a catalyst having a crystalline microporous structure wherein the catal...
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WO/2016/146627A1 |
The present invention relates to a process for the preparation of diaminobutane from ornithine, comprising steps of: i. preparing a solution of (a) a salt of ornithine and an acid; and (b) an aldehyde or a ketone, or a mixture thereof; i...
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WO/2016/143539A1 |
Provided is a bis(aminomethyl)cyclohexane isomerization method wherein bis(aminomethyl)cyclohexane is isomerized while introducing an inert gas into a reaction solution that includes bis(aminomethyl)cyclohexane, at least one type of comp...
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WO/2016/143737A1 |
Provided is a novel polyamine compound represented by formula (1). (In formula (1), R1 and R2 each independently represent a substituent group selected from hydrogen, a C1-10 alkyl group, a C1-10 alkoxy group, a hydroxyl group, an amide ...
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WO/2016/143738A1 |
Provided is an epoxy-resin curing agent containing an alicyclic polyamine compound represented by formula (1). (In formula (1), R represents a substituent group selected from hydrogen, a C1-10 alkyl group, a C1-10 alkoxy group, a hydroxy...
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WO/2016/143637A1 |
[Problem] The present invention addresses the problem of providing a new method that is for manufacturing a primary amine through catalytic hydrogen reduction of a nitrile and that enables obtaining of a primary amine with high selectivi...
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WO/2016/143538A1 |
An isomerization method is provided which enables achieving, easily and with high activity, an isomerization reaction of a specific compound without involving high pressure reactions or complicated multistage processes. This isomerizatio...
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WO/2016/143769A1 |
A mononuclear iron bivalent complex having iron-silicon bonds, which is represented by formula (1), can exhibit an excellent catalytic activity in at least one reaction selected from three reactions, i.e., a hydrosilylation reaction, a h...
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WO/2016/143537A1 |
The purpose of the present invention is to achieve, simply and with high activity, an isomerization reaction of the industrially important compound diaminodicyclohexylmethane without involving complicated multistage processes. This diami...
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WO/2016/143536A1 |
A method of isomerizing cyclohexane diamine is provided which enables achieving, easily and with high activity, an isomerization reaction of cyclohexane diamine without involving high pressure reactions or complicated multistage processe...
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WO/2016/139594A1 |
Disclosed herein is a method comprising the steps of: a) producing a hydrocarbon stream from syngas via a Fischer-Tropsch reaction, wherein the hydrocarbon stream comprises a first C2 hydrocarbon stream comprising ethane and a first ethy...
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WO/2016/120235A1 |
The invention relates to a method for producing isophorone diamine, characterized in that A) isophorone nitrile is hydrogenated in an aminating manner into isophorone diamine directly in one step in the presence of ammonia, hydrogen, a h...
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WO/2016/121691A1 |
Provided is a resin which has a low linear thermal expansion coefficient and a low absorbance. This resin is characterized by comprising at least one structure that is selected from among structures represented by general formula (1) or ...
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WO/2016/116607A1 |
The present invention relates to an improved process for the racemization of (S) -1-aminoindane. (S) -1-aminoindane is formed as a side product in the process of preparation (R) -1-aminoindane by enantiomeric resolution of racemic 1-amin...
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WO/2016/113757A1 |
The present invention provides a novel recyclable catalysts of formula A, [Formula A should be inserted here] wherein X is selected from the group consisting of [Formula should be inserted here] The present invention also provides a nove...
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WO/2016/108941A1 |
The present disclosure provides a method for reducing the aldehyde content in an amine catalyst by treating the amine catalyst with a treating agent selected from a non-cyclic amide substituted with an isocyanate reactive group, a guanid...
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WO/2016/108712A1 |
The invention relates to the field of organic synthesis, and more particularly to a method of producing N,N-disubstituted aminomethylstyrenes or α-aminomethylstyrenes of general formula (I), which includes reacting a secondary amine of ...
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WO/2016/096905A1 |
This invention concerns the first mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalystand amine donor. The initial heterogeneous metal- catalyzed reaction between the ca...
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WO/2016/095870A1 |
Provided are a bisphenol and diamine containing benzocyclobutene structural unit, and preparation and application thereof; specifically, the present invention uses 4-halo-benzocyclobutene as a raw material to obtain 4-acyl-benzocyclobute...
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WO/2016/095136A1 |
Provided is a method for purifying 1,5-pentanediamine comprising: providing 1,5-pentanediamine to be purified and treating the 1,5-pentanediamine to be purified by a reduction reaction to obtain purified 1,5-pentanediamine. Meanwhile, fu...
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WO/2016/097914A1 |
The present invention discloses a process for preparation of white curcumin from purified curcuminoids. The curcuminoids are obtained by solvent extraction and crystallization of dried turmeric powder. The autoclave is charged with ethyl...
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WO/2016/093193A1 |
This method for manufacturing an N,N,N-trimethyl adamantyl ammonium hydroxide has, in sequence, (A) a step for obtaining an N,N-dimethyl adamantyl amine by dimethylating 1-aminoadamantane, (B) a step for reacting the N,N-dimethyl adamant...
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WO/2016/083210A1 |
The invention relates to a method for producing trans-enriched MDACH, characterized in that an MDACH starting mixture is distilled in the presence of an auxiliary agent. Trans-enriched MDACH is distilled, and - the auxiliary agent is an ...
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WO/2016/084565A1 |
Provided is a method for manufacturing a compound having an excellent reaction rate (high reaction rate). The method for manufacturing a compound includes a step for supplying, into a reaction vessel: compound (1) which has at least one ...
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WO/2016/080551A1 |
A catalyst fibrous structure having a catalyst metal carried on a fibrous structure, wherein (a) a Log differential micropore volume distribution curve thereof obtained by measurement using a mercury intrusion technique has a peak having...
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WO/2016/074121A1 |
Providing a process for forming an amine, such as a primary, a secondary or a tertiary amine, via the direct amination of an alcohol using a catalyst comprising at least a palladium compound on a support comprising cerium oxide.
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WO/2016/071249A1 |
The present invention relates to a novel method for producing substituted biphenylamines.
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WO/2016/071410A1 |
Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, wherein the halogen ato...
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