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Matches 1 - 50 out of 686

Document Document Title
WO/2022/092260A1
The present invention addresses the problem of providing a cross-coupling reaction method that can use a wide variety of compounds as starting materials, that can substantially not use organic solvent, and that can rapidly provide reacti...  
WO/2022/090762A1
The present invention concerns dispiroindenopyridines and dispiroindenopyridazines and derivatives thereof, methods for their preparation, the study and definition of their properties, and their uses. In particular, the present invention...  
WO/2022/089598A1
A flavonoid glycoside and organic amine neuroagonist double salt compound, a preparation method therefor, and an application thereof, a pharmaceutical composition containing a therapeutically effective amount of the double salt compound ...  
WO/2022/061920A1
A method for preparing 3',5'-dichloro-2,2,2-trifluoroacetophenone. The method comprises subjecting 3'-chloro-2,2,2-trifluoroacetophenone as a raw material to four steps, i.e. nitrification, reduction, chlorination and deamination, so as ...  
WO/2022/061914A1
The present application relates to the technical field of chemical pharmacy, and in particular, to a method for preparing 3,5-dihalotrifluoroacetophenone and a derivative thereof. 3-halogen-4-nitrotrifluoroacetophenone is used as a raw m...  
WO/2022/058916A1
The present invention disclosed a process for the synthesis of compound of formula (Z) or a salt thereof, wherein, R, R1, R2, R3 and R10 are as defined in the detailed description. The process further comprises the synthesis of an anthra...  
WO/2022/026225A1
The present invention is a method of making 1,4,5,8-tetrakis(R-phenylamino)anthracene-9,10-dione (where R is H or a hydrocarbyl group) comprising the step of contacting 1,4,5,8-tetrachloroanthraquinone with a mixture of R-anilines compri...  
WO/2021/240331A1
The present invention relates to an improved process for the preparation of 3,5-Dichloro-2,2,2-Trifluoroacetophenone of formula (I). The present invention further provides an improved process for the preparation of Fluralaner using 3,5-d...  
WO/2021/234697A1
The present invention pertains to compositions and methods for treating inflammation in a subject in need thereof using hydroxynorketamine (HNK), a salt thereof, a stereoisomer thereof, or a combination thereof.  
WO/2021/233805A1
The present invention relates to a process for purifying 2-(4'-diethylamino-2'-hydroxybenzoyl)benzoic acid hexyl ester providing a high purity and low phthalic acid dialkyl ester content.  
WO/2021/208951A1
Disclosed is a β-diketone cerium (IV) compound of formula (I). The compound has a wide absorption band, is suitable for near ultraviolet-visible region curing as a photoinitiator, and has a high sensitiveness, while also having the adva...  
WO/2021/071033A9
The present invention relates to a method for preparing diethylamino hydroxybenzoyl hexyl benzoate and, specifically, to: a method for preparing diethylamino hydroxybenzoyl hexyl benzoate, which has a simple preparation process and can b...  
WO/2021/189528A1
Disclosed are a thermally activated delayed fluorescent material and a synthesis method therefor, and an electroluminescent device. The thermally activated delayed fluorescent material is a target compound synthesized by reaction of an e...  
WO/2021/138443A1
Methods and compositions for modifying the course and severity of neuropsychiatric disorders. The method includes administering a composition to a subject suffering from a neuropsychiatric disorder, wherein the composition includes a sub...  
WO/2020/251015A1
Provided is a method for producing a substance related to 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione that is suitable for industrial production. The present disclosure provides: a method for producing two production intermediates for 2...  
WO/2020/237748A1
Provided in the present application is a method for preparing a compound having a long-acting therapeutic effect. The compound may be used to prepare antidepressant, anesthetic and analgesic drugs, as well as drugs for cognitive function...  
WO/2020/215388A1
Provided are a deep red light thermally activated delayed fluorescence material, a preparation method therefor, and an electroluminescent device. The deep red light thermally activated delayed fluorescence (TADF) material comprises a com...  
WO/2020/212510A1
The present invention is directed to methods for the asymmetric synthesis of esketamine. The present invention is further directed to key intermediates in the asymmetric esketamine synthesis. In one embodiment, the invention is an asymme...  
WO/2020/212157A1
The invention concerns a new, efficient process for the preparation of enantiomerically pure norepinephrine (also known as noradrenaline), or an addition salt thereof, using a catalytic hydrogenation system under hydrogen donor transfer....  
WO/2020/212890A1
Disclosed herein is a method for synthesizing levomethadone hydrochloride including producing (R)-2-(dimethylamino)propan-1-ol by reducing Ν,Ν-dimethyl-D-alanine using borax, forming (R)-1-chloro-N,N-dimethylpropane-2-amine hydrochlori...  
WO/2020/187155A1
Use of an apocynin dimer analogue derivative in preparing a medicament or a health care product for preventing and treating Parkinson's disease. The structure of the apocynin dimer analogue derivative is as shown in formula I. The apocyn...  
WO/2020/171400A1
The present invention pertains to: a water-soluble naphthoquinone derivative composition and a method for producing same; a water-soluble composition for controlling harmful algae; a method for controlling large-scale harmful algae; and ...  
WO/2020/037372A1
A method of detecting the presence of an NBOMe in a sample which comprises of contacting the sample with an activated p-quinone such as 2,3,5,6-tetrachloro-1,4-benzoquinone (TCBQ) and an aldehyde, for example acetaldehyde, and optionally...  
WO/2020/002338A1
A process for the continuous production of a reaction product of a diazo‐compound and a substrate in a multi‐stage flow reactor is disclosed.  
WO/2019/243369A1
The present invention relates to compounds of formula (I) that are able to generate oct-2-en-4-one and thus to provide a long-lasting or substantive strawberry odor to the environment. Moreover, the present invention relates to a method ...  
WO/2019/236557A1
A process for the preparation of (2R,6R)-hydroxynorketamine is provided. The process requires no chromatography purification and affords the (2R,6R)-hydroxynorketamine in eight steps with a 26% overall yield and greater than 97% purity.  
WO/2019/223015A1
Disclosed are a precursor for a blue anthraquinone active disperse dye and a preparation method therefor. A parent body structure of the precursor is of an anthraquinone structure, has an amino capable of being reacted with an active gro...  
WO/2019/223016A1
Provided are a blue anthraquinone active disperse dye suitable for use in a supercritical CO2 fluid dyeing process and a preparation method therefor. A parent structure of the active disperse dye is of an anthraquinone structure, and als...  
WO/2019/219942A1
Provided is a process for producing an amine via a hydroaminoalkylation reaction of a non-aromatic C-C double bond or C-C triple bond, said process comprising a step of reacting a compound comprising a non-aromatic C-C double bond or C-C...  
WO/2019/199518A1
Processes are disclosed for synthesizing an α-amino acid or α-amino acid derivative, from a starting compound having a carbonyl functional group (C=O), with hydroxy-substituted carbon atoms at alpha (α) and beta (β) positions, relati...  
WO/2019/122204A1
Disclosed are processes for the manufacture of pyrazole compounds of formula (I) and their application in the manufacture of pyrazole derivatives, in particular in processes for the manufacture of pharmaceutically or agrochemically activ...  
WO/2019/047846A1
Derivatives of hypocrellin with peri-position and 2-position simultaneously substituted by amino groups and a preparation method and application thereof are disclosed. The structural formula of the derivatives is as shown in the formulae...  
WO/2019/035775A1
A method for the preparation of tapentadol in the form of a base or its hydrogen chloride, which involves the preparation of a salt (III) from a mixture of diastereomers (II) by means of crystallization-induced asymmetric transformation ...  
WO/2018/170476A1
The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions, in which aldehyde toxicity is implicated in the pathogenesis, by the administration of small molecule t...  
WO/2018/159834A1
Provided are a donor-acceptor type compound having a novel structure and an application of the donor-acceptor type compound. This enamine compound is represented by general formula (1) (in the formula: R1 represents an electron-accepting...  
WO/2018/103239A1
Disclosed is a preparation method for a compound shown by formula (E), a Velpatasvir intermediate shown by formula (K) and an analogue thereof. The method of the present invention uses inexpensive and easily available materials, and a si...  
WO/2018/074411A1
Provided is an efficient and economical method for producing a nitrogen-containing compound. In this method for producing a compound represented by the formula R3C(O)CH=CHNR1R2, a six-fold molar excess of a compound represented by the fo...  
WO/2018/059213A1
Provided are compounds interfering with SAICAR synthesis, and applications. On the basis of existing protein structure data and small molecule structure data, calculations and analysis are performed using software to screen and obtain co...  
WO/2017/067497A9
Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups s...  
WO/2018/013682A1
Covalent organic frameworks (COFs) usually crystallize as insoluble powders and their processing for suitable devices has been thought to be limited. Here, it is demonstrated that COFs can be mechanically pressed into shaped objects havi...  
WO/2017/211129A1
A method for manufacturing an ephedrine or pseudoephedrine intermediate, comprising: using 2-chloropropionyl chloride and benzene as starting raw materials and performing a Friedel-Crafts reaction using a Lewis acid catalyst to generate ...  
WO/2017/137955A1
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop an-1-amine () and its use in improved and ...  
WO/2017/077550A1
The present invention discloses a novel metal free process for the regioselective synthesis of α-substituted carbonyl compounds of formula I from alkene, X is selected from the following compounds (A, B).  
WO/2017/057460A1
Provided is a method for producing an organic compound, wherein the organic compound is an industrially useful compound, and a deodorization step, for removing from a reaction solution odorants that are generated in or remaining after a ...  
WO/2017/054112A1
The present invention relates to a method of preparing a 3-fluoroalkyl-1-methylpyrazole-4-carboxylic acid comprising the following steps: Step 1, performing a condensation reaction on the fluoroacetyl halide derivative shown in formula I...  
WO/2017/035224A1
Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are ...  
WO/2016/207252A1
A method of preparing a compound represented by general formula (3) : Formula (3). R1 and R2 are each independently an alkyl group. The method includes reacting a compound represented by general formula (2) : Formula (2) with an alkylami...  
WO/2016/202254A1
Provided are a preparation method for synthesizing a pyrazolecarboxylic acid derivative of the following formula (I), which is suitable for industrial production, and an intermediate as shown by the following formula (II). The method is ...  
WO/2016/150208A1
Disclosed are a pharmaceutical composition and dosage form containing a glaucocalyxin A derivative as represented by the formula (I) or salt thereof, and a preparation method and use of said composition and dosage form; the anti-autoimmu...  
WO/2016/150206A1
Disclosed is a glaucocalyxin A derivative -- dimethylamino glaucocalyxin A hydrochloride salt -- and two crystalline forms thereof. The dimethylamino glaucocalyxin A hydrochloride salt provided by the present invention has good water sol...  

Matches 1 - 50 out of 686