| Document |
Document Title |
|
WO/2013/030193A1 |
The present invention relates to γ,δ-unsaturated a-amino acids of general formula (I). The present invention also provides a versatile process for the stereospecific synthesis of said compounds of formula (I), involving a Wittig reacti...
|
|
WO/2013/026940A1 |
This invention relates to the simplified radiosynthesis of O-[18F]fluoromethyl tyrosine derivatives whereby the need for purification by preparative high pressure liquid chromatographic methods (HPLC) has been eliminated.
|
|
WO/2013/017782A1 |
The invention relates to a method for synthesizing ω-amino-alkanoic acids or the esters thereof from natural unsaturated fatty acids passing through an intermediate ω-unsaturated nitrile compound. The method of the invention is simple ...
|
|
WO/2013/017786A1 |
A process for synthesizing a long-chain saturated α,ω-amino ester (acid) comprising from 6 to 17 carbon atoms, said process comprising a first step of cross metathesis between a first acrylic compound chosen from acrylonitrile, acrylic...
|
|
WO/2012/150825A9 |
The present invention relates to a method for preparing an optically pure (S)-cyclohexylamino acid derivative by continuously hydrogenating an optically pure (S)-phenylamino acid derivative in the presence of a metal supported catalyst. ...
|
|
WO/2013/011226A1 |
The subject matter of the invention is a process for synthesizing ω-functionalized acids of formula R-(CH2)n-COOH in which R is COOH or NH2CH2, from a feedstock of natural origin containing hydroxylated fatty acids.
|
|
WO/2013/007694A1 |
A process for the preparation of a prodrug of 5-aminosalicylic acid, namely 2-butanoyloxy-5-amino-benzoic acid,and solid forms of such compound are described.
|
|
WO/2013/008104A1 |
The invention relates to a process for the production of (2hydroxyethyl)trimethylammonium [o-(2,6-dichloroanilino)phenyl]acetate and to a solution of (2hydroxyethyl)trimethylammonium [o-(2,6-dichloroanilino)phenyl]acetate in ethanol that...
|
|
WO/2013/007603A1 |
The invention relates to a method for producing 2-amino-5-cyano-N,3-dimethylbenzamide of formula (I) by reacting 2-amino-5-cyano-3-methylbenzoic acid esters or diesters with methylamine.
|
|
WO/2013/005425A1 |
[Problem] To provide a nitrobenzene compound manufacturing method capable of being carried out by simple operations under moderate conditions without the use of special reacting device. [Solution] This invention provides a method for man...
|
|
WO/2012/150155A9 |
What is proposed is a process for preparing a crystalline L-MGDA tri-alkali metal salt by crystallization from an aqueous solution thereof which has been obtained by Strecker synthesis proceeding from L-α-alanine, by reaction with forma...
|
|
WO/2012/176715A1 |
The present invention relates to a 1-amino-2-vinyl cyclopropane carboxylic acid amide or a salt thereof. By obtaining an optically active 1-amino-2-vinyl cyclopropane carboxylic acid amide or a salt thereof by hydrolyzing an optically ac...
|
|
WO/2012/169474A1 |
[Problem] To provide a method for producing a compound having excellent activity as an α2δ ligand. [Solution] This method for producing a compound or a salt thereof having the general formula (VI) via an iminium salt. [In the formula, ...
|
|
WO/2012/169475A1 |
The present invention addresses the problem of providing a method for producing a compound having excellent activity as an α2δ ligand. The solution involves a method for producing a compound or a salt thereof having the general formula...
|
|
WO/2012/165545A1 |
The present invention provides a method that is for producing a peptide, a protected peptide, or a protected amino acid and that contains the precipitation and solid-liquid separation of a C-protected peptide or C-protected amino acid me...
|
|
WO/2012/159952A1 |
The invention relates to a method for producing aminopolycarboxylates starting from the corresponding polyalkanol amines by means of oxidative dehydration in the presence of a catalyst containing 1 to 90 wt.% copper, with respect to the ...
|
|
WO/2012/156888A1 |
The present invention relates to a novel manufacturing process of pharmaceutically active compound of formula (I) used as oral anti-diabetic drug. Starting from -aspartic acid derivate of formula (IV) the invention describes preparation ...
|
|
WO/2012/150204A1 |
This invention relates to novel precursors suitable for 18F radiolabeling of glutamate derivatives, methods for preparing such compounds and its intermediates, compositions comprising such compounds, kits comprising such compounds or com...
|
|
WO/2012/146736A1 |
Salts of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium, method of preparation thereof and use in the treatment of cardiovascular disease.
|
|
WO/2012/147103A2 |
Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of suc...
|
|
WO/2012/139842A1 |
The invention relates to a method for producing amino-polycarboxylates from an amino acid which, in a first method step, is reacted with ethylene oxide to form an intermediate product mixture comprising the corresponding dialkanolamine, ...
|
|
WO/2012/136383A2 |
The invention relates to the preparation of chiral compounds, in particular to the preparation of chiral compounds which may be used as intermediates for the preparation of anti-diabetic agents, preferably sitagliptin.
|
|
WO/2012/136474A1 |
The invention relates to a method for producing aqueous solutions of methylglycine-N,N-diacetic acid trialkali metal salts at a high yield and purity using Strecker synthesis, starting from an aqueous solution of α-alanine, by reacting ...
|
|
WO/2012/120025A1 |
The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging ...
|
|
WO/2012/121068A1 |
In this method of producing optically active 1-amino-2-vinylcyclopropane carboxylic acid ester, a 1-amino-2-vinylcyclopropane carboxylic acid ester and an optically active tartaric acid or an optically active camphorsulfonic acid are rea...
|
|
WO/2012/121079A1 |
Provided is a compound represented by general formula (1). Also provided is a method for producing a compound represented by formula (1) that comprises a reaction step for reacting a compound represented by general formula (2), a compoun...
|
|
WO/2012/117417A1 |
A method for preparing(2R,3S)-2-benzyloxy-3-tert-butoxy-carbonylamino-3-p
henylpropionic acid of formula (I) is provided, and a method for purifying and isolating the compound is also provided. The method uses inexpensive, non-hazardous ...
|
|
WO/2012/113475A1 |
The present invention relates to a chemocatalytic liquid-phase process for the direct single-stage amination of alcohols to primary amines using ammonia in high yields by means of a catalyst system containing at least one transition meta...
|
|
WO/2012/113738A1 |
The present invention relates to a chelating agent precursor that contains glutamic acid N,N-diacetic acid (GLDA) and/or methylglycine N,N-diacetic acid (MGDA) wherein at least one of the carboxylic acid groups is presentas a carboxylic ...
|
|
WO/2012/110124A1 |
The invention relates to a method for removing an organic compound having one or more positive charges from an aqueous solution. Said method consists of the following steps a) the aqueous solution containing the organic compound, and a h...
|
|
WO/2012/110126A1 |
The invention relates to a method for removing an organic compound comprising one or more positive charges from an aqueous solution. Said method consists of the following steps: a) the aqueous solution containing the organic compound and...
|
|
WO/2012/110125A1 |
The invention relates to a method for removing an organic compound having one or more positive charges from an aqueous solution. Said aqueous solution also comprises a cell and the method consists of the following steps: a) the aqueous s...
|
|
WO/2012/105873A1 |
The invention relates to the pharmaceutical industry and to medicine, specifically to novel hydrated amino-acid derivatives of fullerene С60 of general formula C60(H)3{NH(CH2)nCOOH}3⋅xH2O, where С60 - fullerene, n = 5, 6, 7, х = 8 -...
|
|
WO/2012/105872A1 |
The invention relates to the pharmaceutical industry and to medicine, specifically to novel homo- and hetero-polyamino-acid derivatives of fullerene С60 of general formula: C60(H)x{NH(CH2)nCOO-}x{NH3 +(L)COOH)}x, where n = 2-5, х = 3, ...
|
|
WO/2012/100419A1 |
Disclosed is a process for synthesis of 3-(N,N-disubstituted-amino)-2-substituted acrylate, which comprises carrying out amine-substitution reaction and elimination reaction for 2-substituted formylacetate alkali metal salt represented b...
|
|
WO/2012/095575A1 |
The invention relates to a process for synthesizing a nitrile-fatty acid (heminitrile) from unsaturated fatty acids, in the form of an acid or a simple ester or a "complex" ester of triglyceride type, which is first of all converted into...
|
|
WO/2012/093411A2 |
The invention provides a process for resolution of R (±) - 3- (carbamoylmethyl)-5-methylhexanoic acid I to form enantiomerically pure form of compound of formula (I), the said process comprises resolution of racemic mixture of compound ...
|
|
WO/2012/083753A1 |
Disclosed is a process for preparing 5-aminosalicylic acid by gas phase catalytic carboxylation, characterized in that carbon dioxide is introduced into a system of p-acetaminophenol and a basic compound at a temperature of 150°C - 220...
|
|
WO/2012/087177A1 |
The invention relates to the field of chemical engineering and biotechnology, in particular to methods for converting protein-containing materials and for using protein-containing waste to produce mixtures of natural amino acids, mixture...
|
|
WO/2012/076560A1 |
The present invention provides a process for preparing primary amines, comprising the steps of A) providing a solution of a primary alcohol in a fluid, non-gaseous phase, B) contacting the phase with free ammonia and/or at least one ammo...
|
|
WO/2012/073506A1 |
[Problem] To provide a stable industrially-manufactured intermediate, enabling an industrially stable supply of 2-pyridyl-benz[d][1,3]oxazine to be provided. [Solution] The compound represented by formula (6) (wherein M represents sodium...
|
|
WO/2012/072567A1 |
The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabeled amino acids for use in in vivo imaging p...
|
|
WO/2012/062041A1 |
Disclosed are aromatic ketone compounds with para- or meso-substituted multifunctional groups as represented by the general formulae I-III, preparation methods thereof, and free-radical polymerization photoinitiators comprising the compo...
|
|
WO/2012/064168A1 |
The invention relates to the use of zwitterionic geminal liquids of type bis-N-alkyl polyether or bis-N-alkenyl polyether or bis-N-aryl polyether bis-beta imino acids or the salts thereof as modifiers of the wettability of rock, such as ...
|
|
WO/2012/059797A1 |
Improved process for the synthesis of (S)-pregabalin having more than 99% ee through (S) 3-cyano-5-methyl-hexanoic acid has been developed. In addition to above, a novel process for resolution of (RS) - 3-cyano-5-methyl-hexanoic acid thr...
|
|
WO/2012/055455A1 |
The invention pertains to a new route to prepare β-functionalized carboxylic acid esters in a one-pot reaction, by reacting an olefinic acid ester in the presence of a catalyst system, comprising a Rh(I)-complex, together with an aryl b...
|
|
WO/2012/048043A1 |
Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, intermixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt i...
|
|
WO/2012/045967A1 |
The invention relates to a method for preparing an amino acid, or the salts thereof, from 2-aminobutyrolactone (2ABL), wherein said amino acid has formula I, XCH2CH2CHNH2COOH, where X is a nucleophilic ion and, wherein according to the m...
|
|
WO/2012/040853A1 |
The present invention provides Group 5 metal complexes useful for amine functionalization and synthetic process for manufacture thereof. Provided in this application are halo group 5 metal-amidate complexes having the structure of Formul...
|
|
WO/2012/041741A1 |
What is proposed is a process for producing granules comprising one or more complexing agent salts of the general formula (I) formed from an aqueous starting solution comprising the one or more complexing agent salts in a concentration o...
|
