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WO/2023/104063A1 |
A preparation method for ioversol hydrolysate, comprising: with an industrial iodide as a raw material, subjecting the industrial iodide and acetoxyacetyl chloride to an acetoxyacetylation reaction, hydrolyzing same, and regulating the a...
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WO/2023/104017A1 |
The present disclosure provides compounds that can inhibit the type III secretion system (TTSS) to decrease the pathogenesis of gram-negative bacteria. These compounds may have wide applications for treating bacteria diseases caused by g...
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WO/2023/099283A1 |
The present invention is related to a method for purifying crude α-sulfo fatty acid salt obtained by the reaction of fatty acid and sulfur oxides, comprising the following steps: a) diluting the crude α-sulfo fatty acid in a solvent an...
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WO/2023/098592A1 |
The present invention provides a carbon-loaded iron-based catalyst, and a preparation method thereof and a use. The preparation method comprises dissolving ferric chloride in water, adding activated carbon, adding sodium hydroxide at 60-...
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WO/2023/093560A1 |
The present invention discloses a method for preparing an N-fatty acyl amino acid surfactant by means of high-temperature melting and direct condensation. The method of the present invention comprises: mixing a fatty acid, a catalyst and...
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WO/2023/090086A1 |
Provided are a secondary monohydrofluoroalkane selective adduct and a method for producing the same. A compound represented by formula (3) is produced by means of a method including a step for reacting a compound represented by formula (...
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WO/2023/090859A1 |
The present invention relates to: a novel method for preparing an isoxazole derivative, which is useful as a farnesoid X receptor (FXR, NR1H4) agonist; a novel intermediate used in the preparation method; and a method for preparing the p...
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WO/2023/078277A1 |
An intermediate of a polyamine derivative, a preparation method therefor, and a use thereof. The intermediate is easy to prepare and high in purity; and when the intermediate is used for preparing the polyamine derivative, the obtained p...
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WO/2023/078722A1 |
The present invention relates to new specific butyrate compounds to a new and improved synthesis of specific butyrates as well their use. Butyrate compounds are very useful compounds, either as such or as intermediates in organic synthesis.
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WO/2023/073502A1 |
The present invention relates to methods for preparation of 2-amino-5-chloro-N-3-dimethylbenzamide compound of Formula (IV) and pyrazole-carboxylate compound of Formula (VI), an intermediates useful for preparation of certain anthranilam...
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WO/2023/073080A1 |
The present invention relates to a process for preparing aromatic acyl derivatives of formula (I) using methanesulfonic acid. The invention further relates to methods for preparing biological active ingredients, such as paracetamol.
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WO/2023/072998A1 |
The present invention relates to an improved method for preparing and isolating hydrogen cyanide, said method comprising the reaction of methane (e.g. natural gas), ammonia and optionally oxygen, wherein C2-C10 nitrile by-products, such ...
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WO/2023/061101A1 |
Disclosed are an HDAC/MAO-B dual inhibitor, the preparation thereof, and an application in the preparation of a drug and neuroprotective antioxidant for preventing and treating related diseases by inhibiting monoamine oxidase and histone...
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WO/2023/063466A1 |
Disclosed is a method for preparing a ceramide compound. Specifically, provided is a method for synthesizing ceramide by reaction of phytosphingosine and a methyl ester-based compound represented by chemical formula 2, as starting materi...
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WO/2023/060955A1 |
Provided in the present invention is a synthetic method for cetyl-PG hydroxyethyl palmitamide. The method comprises the following steps: firstly, mixing 1,3-dichloropropanol and hexadecyl alcohol under the action of a catalyst and an alk...
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WO/2023/056957A1 |
A solvent system of a working solution for producing hydrogen peroxide by means of an anthraquinone method. The solvent system comprises the following components or are composed of the following components in parts by volume: A) 2-60 par...
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WO/2023/054350A1 |
The present invention provides a production method for purified dichloroacetic acid and an efficient production method for nucleic acid molecules using same. Specifically, the present invention provides: a production method for purified ...
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WO/2023/053877A1 |
Provided are: a compound suitable for use as a photodisintegrable base for resist compositions which have satisfactory sensitivity to actinic energy, e.g., EB or EUV, have excellent resolution in lithography, and can give fine patterns r...
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WO/2023/055050A1 |
The present invention relates to: a method for removing a compound of chemical formula 1, comprising the step of adding a metal hydroxide compound to a composition comprising chemical formula 1 and a water-soluble solvent; and a method f...
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WO/2023/045371A1 |
Disclosed is a novel cationic lipid compound represented by formula (A), or an isomer, an N-oxide, a pharmaceutically acceptable salt, or a prodrug thereof. Further disclosed are a preparation method, a composition and an application of ...
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WO/2023/046815A1 |
The invention is related to a process for preparing a iodinating X-rays contrast agent. More specifically, it relates to a process for the preparation of N,N'-bis-(2,3-dihydroxypropyl)-5-hydroxy-2,4,6-triiodo-1,3-b
enzenedicarboxamide (I...
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WO/2023/039941A1 |
Provided are an N,N,N-triacyl-2,4,6-triaminotoluene compound nucleating agent, and a preparation method therefor and a use method thereof. The nucleating agent is used for polymer nucleation at high temperatures, and can effectively redu...
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WO/2023/041515A2 |
The invention provides a method for preparing an aqueous (meth)acrylamide solution, said method comprising the following steps: (a) adding the following components (i) to (iii) to a reactor to obtain a composition for bioconversion: (i) ...
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WO/2023/039940A1 |
Disclosed is a method for preparing N,N,N-tripivaloyl-1,3,5-triaminobenzene. The method comprises: step 1, using 2,4,6-trinitrotoluene as a raw material, and reacting same with hydrogen and pivalic anhydride in sequence to obtain N,N,N-t...
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WO/2023/040106A1 |
Disclosed in the present invention is a preparation method for an acetamide compound by means of green visible-light catalysis. In the method, LED lamps are used as light sources to provide energy, and economically available aromatic ami...
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WO/2023/042716A1 |
A production method for a (meth)acrylamide compound that includes a step for reacting (meth)acrylic acid with a primary amine compound in the presence of a condensing agent to synthesize a (meth)acrylamide compound (X).
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WO/2023/041209A1 |
The present invention relates to a process for the preparation of spherical agglomerates of safinamide or a pharmaceutically acceptable salt thereof, to the agglomerates thus obtained and to a process for preparing a pharmaceutical compo...
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WO/2023/039068A1 |
The present disclosure provides intermediates for the synthesis of peptide nucleic acid (PNA) backbones and monomers, such as cyclic intermediates, and methods of making the same.
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WO/2023/036955A1 |
The present invention relates to the use of an M-NHC catalyst, in which M is Pd or Pt and NHC is an N-heterocyclic carbene group, comprising at least one M atom bonded to at least one N-heterocyclic carbene ligand, in the implementation ...
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WO/2023/036952A1 |
The present invention relates to a new palladium-based catalyst on a cerium dioxide substrate, of the formula Pd-X/Ce02, wherein X represents the empty set or a doping agent and its use in the implementation of a method for selectively p...
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WO/2023/030043A1 |
Disclosed are a tricyclic diterpene analogue represented by formula (I) and a preparation method therefor. By using testosterone as a raw material, and by means of methylation, ethylene glycol protection, oxidation, Baeyer-Villiger oxida...
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WO/2023/028022A1 |
A method of synthesizing a pharmacological compound substance by attaching a psychoactive base substance to an amino acid and creating a prodrug with modified pharmacological behavior. A prodrug made by the method. A pharmaceutical compo...
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WO/2023/025138A1 |
Disclosed are novel exatecan mesylate intermediates 5 and A, and a preparation method for exatecan mesylate. Raw materials in the preparation method are cheap and easy to obtain, the synthetic route of the intermediate is simple, the "on...
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WO/2023/014050A1 |
The present invention relates to a method for efficiently recovering dimethylformamide at high purity from a waste solution resulting from the production of a polyimide. The method according to the present invention is directed to a meth...
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WO/2023/012205A1 |
The present invention relates to new specific butyrate compounds to a new and improved synthesis of specific butyrates as well their use. Butyrate compounds are very useful compounds, either as such or as intermediates in organic synthesis.
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WO/2023/004687A1 |
Provided by the present invention is an unnatural amino acid, which is a compound having a structure as shown in formula (I) or an enantiomer thereof. Further provided by the present invention is an application of the unnatural amino aci...
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WO/2023/001267A1 |
A preparation method for an N-long-chain acyl amino acid dipeptide, supramolecular amino acid and corresponding salts thereof, capable of controlling the occurrence of structural reconstruction and controlling the content of long-chain f...
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WO/2023/285581A1 |
The present invention relates to a method of making sodium N-(8-2-Hydroxybenzoyl)amino caprylate form A, SNAC polymorphic form A having improved stability and the use of said SNAC polymorphic form A in a solid pharmaceutical dosage form-
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WO/2023/283831A1 |
Disclosed in the present invention is a compound having an inhibitory effect on a virus main protease (3CL protease, Mpro), which also has a significant inhibitory activity on the Mpros of SARS coronavirus (SARS-CoV) and novel coronaviru...
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WO/2023/281088A2 |
The present invention relates to a biological method for obtaining an MO monomer comprising an ethylenic unsaturation by bioconversion of a CN compound comprising at least one nitrile function, said CN compound being at least partially r...
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WO/2023/281081A1 |
The present invention relates to a method for obtaining substituted alkyl(meth)acrylamide comprising the reaction between (meth)acrylic acid or one of the esters thereof on the one hand, and a primary or a secondary alkylamine on the oth...
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WO/2023/281086A1 |
The present invention relates to a method for obtaining N-vinylformamide comprising the reaction between an acetaldehyde and a formamide, one of the two, preferably both, being at least partially renewable and non-fossil. The invention f...
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WO/2023/277587A1 |
The present specification relates to a method for preparing an N-acyl derivative by distilling a first composition comprising a compound of chemical formula 1, and using the distilled first composition, an N-acyl derivative prepared ther...
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WO/2023/275091A1 |
An improved preparation of non-steroidal antiandrogen drugs, such as 4-[3-[4-cyano-3- (trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imida
zolidinyl]-2-fluoro-N-methyl- benzamide and intermediates thereof, is described.
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WO/2023/277590A1 |
The present specification relates to: a method for preparing alkyl-D-alaninate, the method comprising a step for distilling a composition, which includes a compound of chemical formula 3 synthesized by reacting chemical formula 1 and che...
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WO/2023/272497A1 |
The present application provides N,N-dihydrocarbonyl amino carboxylic acid, a preparation method therefor, and the use thereof. The N,N-dihydrocarbonyl amino carboxylic acid can act as an extracting agent for enriching rare-earth element...
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WO/2022/266919A1 |
Provided are an N,N-dihydrocarbyl amide carboxylic acid, a preparation method therefor and a use thereof. The N,N-dihydrocarbyl amide carboxylic acid can be used as an extractant to enrich rare earth elements from a low-concentration rar...
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WO/2022/264166A1 |
The present invention relates to process for the preparation of pure Salcaprozate sodium free of color impurities.
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WO/2022/265115A1 |
A method of producing a polypeptide compound, wherein a peptide compound represented by formula (P) is obtained by inducing an amide formation reaction between an amino-protected lactam compound represented by formula (R1) and an amino a...
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WO/2022/261634A1 |
Surfactant compositions and derivatives with low amounts of impurities are disclosed along with a method of making the same. A surfactant composition includes greater than 80% by weight of N-acyl amino acid surfactant of formula (I) and ...
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