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WO/2024/078483A1 |
The present invention belongs to the technical field of biological medicines. Disclosed is a novel ceramide which has a structure represented as formula I. Further disclosed in the present invention are a preparation method for and the u...
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WO/2024/074641A1 |
The present invention relates to a method for preparing of an amide of the formula (I-1) or a diamide of the formula (I-2) where the variables areas defined in the claims and the description, by reacting an ester with an aromatic or hete...
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WO/2024/069507A1 |
This invention relates to novel processes for synthesizing N-(3-(6-Amino-5-(2-(N- methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphe
nyl)-4-cyclopropyl-2-fluorobenzamide and to intermediates which are used in such processes.
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WO/2024/067610A1 |
The present application provides a method for preparing L-glufosinate. The method mainly comprises the following steps: addition and rearrangement and ring-opening reactions on a ring lactone with a substituted phosphate-type phosphine r...
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WO/2024/071372A1 |
The present disclosure provides an oxidative cleavage method of a Trolox amide. More particularly, the disclosure provides a method for producing a compound of formula I, the method including a step for contacting a compound of formula I...
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WO/2024/050715A1 |
Provided in the present application are amide compounds having amino groups on both ends, having general formula (I), in which A and B are independently selected from substituted or unsubstituted C1-C18 alkylene groups, C2-C18 alkenylene...
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WO/2024/046175A1 |
Disclosed is a bis((N-3-aminopropyl)-(N-(3,4-dimethoxyphenylpropionyl)))ami
nopropylamine phosphate, a crystal form thereof, and a preparation method therefor. Compared to a free base and other salts of bis((N-3-aminopropyl)-(N-(3,4-dime...
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WO/2024/048438A1 |
The present invention addresses the problem of providing: a diastereomer preparation method whereby it becomes possible to produce a desired diastereomer from a diastereomer mixture with high efficiency; and a solid-phase photosensitizer...
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WO/2024/041460A1 |
The present invention provides compounds of Formula (I) : wherein all of the variables are as defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for the...
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WO/2024/040745A1 |
The present application provides an amide compound containing iodo aryl or iodo heteroaryl, and a preparation method therefor and a use thereof. The amide compound containing iodo aryl or iodo heteroaryl can be used for preparing an X-ra...
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WO/2024/039293A1 |
The present disclosure relates to a method of synthesising hexamethylenediamine and adipic acid. The method comprises homocoupling of acrylamide under conditions including using oxalic acid as a reductant and irradiating a reaction mixtu...
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WO/2024/032081A1 |
The present invention provides a preparation method for semaglutide, and an intermediate. The preparation method comprises the steps of: (1) reacting compound SEM110 and compound SEM120 in a solvent under an alkaline condition to obtain ...
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WO/2024/034746A1 |
The present invention relates to a method for producing a chiral carbonyl derivative using an (R,R)-1,2-diphenylethylenediamine (DPEN)-based thiourea catalyst compound. According to the production method, a chiral carbonyl derivative hav...
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WO/2024/031970A1 |
The present invention relates to a compound having a chemical formula (I), and further relates to a preparation method therefor and use thereof. Pharmacological experiment results show that the compound of the present invention has excel...
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WO/2024/028999A1 |
The present invention addresses the problem of providing a method for efficiently producing an N-[4-methylaminobenzoyl]-L-glutamic acid diethyl ester, which is a pharmaceutical intermediate. In this method for producing an N-[4-methylami...
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WO/2024/018762A1 |
The present invention addresses the problem of providing, without using relatively expensive starting materials, a more conveniently synthesizable pH-sensitive cationic lipid, and providing a lipid nanoparticle that contains this pH-sens...
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WO/2024/011415A1 |
Disclosed in the present invention is a method for preparing an o-iodophenyl compound, wherein an iodobenzene compound and an amide compound as raw materials are reacted in the presence of sodium hydride or n-butyllithium and a solvent t...
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WO/2024/013769A1 |
The present invention relates to a novel process for the solvent free continuous synthesis of amides and peptides. More particularly, the invention relates to a process for synthesizing amides and peptides using coupling reagents where t...
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WO/2024/007851A1 |
A catalyst for amide synthesis and preparation and use thereof are disclosed. The catalyst is a thio or seleno pyranodipyrimidine compound and has a simple and novel structure, high catalytic efficiency, and good atom economy. The cataly...
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WO/2024/003797A1 |
The present invention relates to pure salts of amphetamine prodrug, in particular, L-lysine-d- amphetamine (known as lisdexamfetamine) and industrial advantageous process for preparation thereof. The present invention relates to the crys...
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WO/2024/003671A1 |
A formulation for decreasing aldehyde content in a polymeric material includes a compound which includes at least three moieties of formula (A) wherein each moiety (A) includes an amine moiety (-NH2) bonded ortho or meta to the amide moi...
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WO/2023/249414A1 |
The present invention relates to a method for producing a benzoamine derivative, and more specifically, to a method for producing a benzoamine derivative at high yield and purity using 1,1'-carbonyldiimidazole as a coupling catalyst in o...
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WO/2023/240790A1 |
Disclosed in the present invention is a method for preparing an N-formyl amide compound under the catalysis of visible light. In the method, an LED lamp is used as a light source to provide energy, economical and easily available seconda...
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WO/2023/240791A1 |
Disclosed in the present invention is an environment-friendly preparation method for an N-methylamide compound. An LED lamp is used as a light source to provide energy, an economical and easily available tertiary amide is used as a react...
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WO/2023/237702A1 |
The present invention pertains to a continuous or semi-continuous process for producing a pre-activated organogelator paste, wherein the process comprises : (1) mixing at least one amide compound with at least one liquid carrier so as to...
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WO/2023/234425A1 |
The present invention provides a novel active ester of an amino acid to be used for amino acylation of tRNA, said ester being capable of reducing risks to safety and waste. The present invention provides a compound represented by formula...
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WO/2023/226263A1 |
The present invention relates to the technical field of organic synthesis, in particular to an anilinoacetate and a synthesis method therefor. The synthesis method for an anilinoacetate comprises: S1, adding an anilinoacetate solution an...
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WO/2023/221851A1 |
Provided is a method for preparing valproamide represented by chemical structural formula I and sodium valproate represented by formula II. The method is characterized in that cyanoacetate and 1-chloropropane are subjected to composite c...
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WO/2023/223885A1 |
The present invention provides a production method for an amide group-containing monomer. With the present invention, an amide group-containing monomer in which the amount of impurities is low is efficiently produced, the production meth...
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WO/2023/214694A1 |
The present invention relates to a method for separating and recovering acetic acid and dimethylformamide from waste solvent, the method comprising the steps of: introducing a waste solvent containing water, acetic acid, and dimethylform...
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WO/2023/209165A1 |
The invention relates to a process for the preparation of a 2,4,6-triiodo-phenol derivative of formula (II), which is useful as an intermediate for the synthesis of conventional X-ray contrast agents, said process comprising the tri-iodi...
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WO/2023/208020A1 |
Disclosed are an intermediate of a polyamine derivative pharmaceutical salt, a preparation method therefor, and use thereof. The intermediate compound has the following structure: (I), which can be used to prepare a polyamine derivative ...
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WO/2023/202559A1 |
The application provides a phenyl acrylic compound, and a preparation method and application thereof. The phenyl acrylic compound has a structure as shown in formula (I). The phenyl acrylic compound provided by the present application ca...
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WO/2023/201712A1 |
The present invention provides a clofoctol derivative, which has a structure represented by general formula (1). The clofoctol derivative has high efficiency, low toxicity, wide antibacterial spectrum, fast sterilization speed, excellent...
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WO/2023/198484A1 |
The invention relates to an improved process for recovering N,N-Dimethylformamide (DMF) from an aqueous process stream by adjusting the pH, extracting with Chloroform and subsequent distillation/rectification.
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WO/2023/193341A1 |
Provided are a sphingolipid compound shown in formula (I), a liposome containing the sphingolipid compound, and an application. The sphingolipid compound is prepared by taking a long-chain alkyl group as a hydrophobic tail part, and bond...
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WO/2023/187049A1 |
The present invention relates to a process for separating at least one ε-caprolactam oligomeric compound CPO from a stream SR comprising said at least one CPO and ε-caprolactam monomeric compound CPM.
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WO/2023/190187A1 |
Provided is a maleimide compound having a partial structure represented by -CH(CF3)-. Also provided is a maleamic acid compound having a partial structure represented by -CH(CF3)-. Also provided is a curable compound comprising the malei...
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WO/2023/170715A1 |
The present disclosure provides a compound of Formula (I), its analogs, tautomeric forms, stereoisomers, enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The present disclosure also provides a process for prepari...
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WO/2023/171617A1 |
[Problem] The present invention addresses the problem of providing a novel method for, under simpler and stabler conditions, labeling a radionuclide such as 211At at a high radiochemical yield. [Solution] Provided is a method for produci...
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WO/2023/166346A1 |
Described herein are methods of making crystalline Form 1 of 2-(4-methoxy-3-(3- methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxyl
ic acid.
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WO/2023/156605A1 |
The present invention relates to a novel and efficient method for the production of sphingolipids via the N-acylation of lysosphingolipids such as D-eritro-sphingosine or 6-hydroxy D-eritro-sphingosine, analogues thereof, or salts thereo...
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WO/2023/151157A1 |
A chemical intermediate and a preparation method, belonging to the technical field of dye intermediate synthesis. The chemical intermediate provides a new way for preparing anthraquinone dyes and dye intermediates. The preparation method...
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WO/2023/151293A1 |
Disclosed in the present invention is a p-phenylcyclobutanamide rosemary compound and a preparation method therefor, and a use of the compound as a hyaluronidase inhibitor and an anti-aging beauty product. Specifically, disclosed in the ...
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WO/2023/148138A1 |
The present invention relates to compounds which are suitable as hair repair agents or fabric repair agents, to compositions and kits comprising such compounds, to the use of such compounds as hair repair agents or fabric repair agents, ...
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WO/2023/145372A1 |
The present invention provides a method for producing a compound represented by formula (3) (wherein R1 and R2 each independently represent a hydrogen atom or a C1-C6 alkyl group and Rf is a C1-C6 alkyl group containing a fluorine atom),...
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WO/2023/142167A1 |
A cationic lipid analog, and a composition and use thereof. Aldehyde compounds, amine compounds, carboxylic acid compounds, and isonitrile compounds are used as starting materials, by means of an Ugi reaction, for synthesizing the cation...
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WO/2023/140435A1 |
The present invention relates to a method for synthesizing Avenanthramides C. The method allows synthesis to be high-yielding despite using a reagent that is easy to manipulate relative to those used in existing synthesis methods, and th...
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WO/2023/132352A1 |
The present invention provides a method that is for producing an amide compound, that comprises obtaining an amide compound by causing a reaction between a carboxylic acid compound and an amine compound in the presence of a condensing ag...
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WO/2023/123695A1 |
The present invention belongs to the technical field of drug synthesis, and particularly relates to a dichloroacetic-acid-coupled diphenylethane compound, and a preparation method therefor and the use thereof. The structure of the dichlo...
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