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WO/2023/234425A1 |
The present invention provides a novel active ester of an amino acid to be used for amino acylation of tRNA, said ester being capable of reducing risks to safety and waste. The present invention provides a compound represented by formula...
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WO/2023/226263A1 |
The present invention relates to the technical field of organic synthesis, in particular to an anilinoacetate and a synthesis method therefor. The synthesis method for an anilinoacetate comprises: S1, adding an anilinoacetate solution an...
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WO/2023/221851A1 |
Provided is a method for preparing valproamide represented by chemical structural formula I and sodium valproate represented by formula II. The method is characterized in that cyanoacetate and 1-chloropropane are subjected to composite c...
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WO/2023/223885A1 |
The present invention provides a production method for an amide group-containing monomer. With the present invention, an amide group-containing monomer in which the amount of impurities is low is efficiently produced, the production meth...
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WO/2023/214694A1 |
The present invention relates to a method for separating and recovering acetic acid and dimethylformamide from waste solvent, the method comprising the steps of: introducing a waste solvent containing water, acetic acid, and dimethylform...
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WO/2023/209165A1 |
The invention relates to a process for the preparation of a 2,4,6-triiodo-phenol derivative of formula (II), which is useful as an intermediate for the synthesis of conventional X-ray contrast agents, said process comprising the tri-iodi...
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WO/2023/208020A1 |
Disclosed are an intermediate of a polyamine derivative pharmaceutical salt, a preparation method therefor, and use thereof. The intermediate compound has the following structure: (I), which can be used to prepare a polyamine derivative ...
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WO/2023/202559A1 |
The application provides a phenyl acrylic compound, and a preparation method and application thereof. The phenyl acrylic compound has a structure as shown in formula (I). The phenyl acrylic compound provided by the present application ca...
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WO/2023/201712A1 |
The present invention provides a clofoctol derivative, which has a structure represented by general formula (1). The clofoctol derivative has high efficiency, low toxicity, wide antibacterial spectrum, fast sterilization speed, excellent...
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WO/2023/198484A1 |
The invention relates to an improved process for recovering N,N-Dimethylformamide (DMF) from an aqueous process stream by adjusting the pH, extracting with Chloroform and subsequent distillation/rectification.
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WO/2023/193341A1 |
Provided are a sphingolipid compound shown in formula (I), a liposome containing the sphingolipid compound, and an application. The sphingolipid compound is prepared by taking a long-chain alkyl group as a hydrophobic tail part, and bond...
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WO/2023/187049A1 |
The present invention relates to a process for separating at least one ε-caprolactam oligomeric compound CPO from a stream SR comprising said at least one CPO and ε-caprolactam monomeric compound CPM.
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WO/2023/190187A1 |
Provided is a maleimide compound having a partial structure represented by -CH(CF3)-. Also provided is a maleamic acid compound having a partial structure represented by -CH(CF3)-. Also provided is a curable compound comprising the malei...
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WO/2023/170715A1 |
The present disclosure provides a compound of Formula (I), its analogs, tautomeric forms, stereoisomers, enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The present disclosure also provides a process for prepari...
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WO/2023/171617A1 |
[Problem] The present invention addresses the problem of providing a novel method for, under simpler and stabler conditions, labeling a radionuclide such as 211At at a high radiochemical yield. [Solution] Provided is a method for produci...
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WO/2023/166346A1 |
Described herein are methods of making crystalline Form 1 of 2-(4-methoxy-3-(3- methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxyl
ic acid.
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WO/2023/156605A1 |
The present invention relates to a novel and efficient method for the production of sphingolipids via the N-acylation of lysosphingolipids such as D-eritro-sphingosine or 6-hydroxy D-eritro-sphingosine, analogues thereof, or salts thereo...
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WO/2023/151157A1 |
A chemical intermediate and a preparation method, belonging to the technical field of dye intermediate synthesis. The chemical intermediate provides a new way for preparing anthraquinone dyes and dye intermediates. The preparation method...
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WO/2023/151293A1 |
Disclosed in the present invention is a p-phenylcyclobutanamide rosemary compound and a preparation method therefor, and a use of the compound as a hyaluronidase inhibitor and an anti-aging beauty product. Specifically, disclosed in the ...
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WO/2023/148138A1 |
The present invention relates to compounds which are suitable as hair repair agents or fabric repair agents, to compositions and kits comprising such compounds, to the use of such compounds as hair repair agents or fabric repair agents, ...
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WO/2023/145372A1 |
The present invention provides a method for producing a compound represented by formula (3) (wherein R1 and R2 each independently represent a hydrogen atom or a C1-C6 alkyl group and Rf is a C1-C6 alkyl group containing a fluorine atom),...
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WO/2023/142167A1 |
A cationic lipid analog, and a composition and use thereof. Aldehyde compounds, amine compounds, carboxylic acid compounds, and isonitrile compounds are used as starting materials, by means of an Ugi reaction, for synthesizing the cation...
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WO/2023/140435A1 |
The present invention relates to a method for synthesizing Avenanthramides C. The method allows synthesis to be high-yielding despite using a reagent that is easy to manipulate relative to those used in existing synthesis methods, and th...
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WO/2023/132352A1 |
The present invention provides a method that is for producing an amide compound, that comprises obtaining an amide compound by causing a reaction between a carboxylic acid compound and an amine compound in the presence of a condensing ag...
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WO/2023/123695A1 |
The present invention belongs to the technical field of drug synthesis, and particularly relates to a dichloroacetic-acid-coupled diphenylethane compound, and a preparation method therefor and the use thereof. The structure of the dichlo...
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WO/2023/124736A1 |
The present invention relates to the technical field of medical materials, and provides an X-ray developable molecule, an X-ray developable embolic microsphere and a preparation method therefor, comprising the following steps: step 1, pr...
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WO/2023/124236A1 |
The present invention relates to the preparation of an antiviral drug, and in particular to an intermediate product for synthesizing Paxlovid and a preparation method. The structures of two intermediate products for synthesizing Paxlovid...
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WO/2023/121380A1 |
The present invention relates to lipids for drug delivery, nanoparticles comprising same, and a composition for drug delivery comprising the nanoparticles. More specifically, the present invention relates to: lipids useful for drug deliv...
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WO/2023/117667A1 |
The present invention relates to a novel process for the preparation of 2,4,6-triiodoisophthalic bisamide derivatives, which are useful intermediates in the preparation of non-ionic X-ray contrast agents, starting from the corresponding ...
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WO/2023/105516A2 |
The present disclosure relates to a process for preparing a N-substituted acetamide, the process including the steps of: (a) reacting an aniline or derivative thereof with a first amount of a chlorinated acyl chloride in presence of a mi...
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WO/2023/104063A1 |
A preparation method for ioversol hydrolysate, comprising: with an industrial iodide as a raw material, subjecting the industrial iodide and acetoxyacetyl chloride to an acetoxyacetylation reaction, hydrolyzing same, and regulating the a...
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WO/2023/104017A1 |
The present disclosure provides compounds that can inhibit the type III secretion system (TTSS) to decrease the pathogenesis of gram-negative bacteria. These compounds may have wide applications for treating bacteria diseases caused by g...
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WO/2023/099283A1 |
The present invention is related to a method for purifying crude α-sulfo fatty acid salt obtained by the reaction of fatty acid and sulfur oxides, comprising the following steps: a) diluting the crude α-sulfo fatty acid in a solvent an...
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WO/2023/098592A1 |
The present invention provides a carbon-loaded iron-based catalyst, and a preparation method thereof and a use. The preparation method comprises dissolving ferric chloride in water, adding activated carbon, adding sodium hydroxide at 60-...
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WO/2023/093560A1 |
The present invention discloses a method for preparing an N-fatty acyl amino acid surfactant by means of high-temperature melting and direct condensation. The method of the present invention comprises: mixing a fatty acid, a catalyst and...
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WO/2023/090086A1 |
Provided are a secondary monohydrofluoroalkane selective adduct and a method for producing the same. A compound represented by formula (3) is produced by means of a method including a step for reacting a compound represented by formula (...
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WO/2023/090859A1 |
The present invention relates to: a novel method for preparing an isoxazole derivative, which is useful as a farnesoid X receptor (FXR, NR1H4) agonist; a novel intermediate used in the preparation method; and a method for preparing the p...
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WO/2023/078277A1 |
An intermediate of a polyamine derivative, a preparation method therefor, and a use thereof. The intermediate is easy to prepare and high in purity; and when the intermediate is used for preparing the polyamine derivative, the obtained p...
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WO/2023/078722A1 |
The present invention relates to new specific butyrate compounds to a new and improved synthesis of specific butyrates as well their use. Butyrate compounds are very useful compounds, either as such or as intermediates in organic synthesis.
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WO/2023/073502A1 |
The present invention relates to methods for preparation of 2-amino-5-chloro-N-3-dimethylbenzamide compound of Formula (IV) and pyrazole-carboxylate compound of Formula (VI), an intermediates useful for preparation of certain anthranilam...
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WO/2023/073080A1 |
The present invention relates to a process for preparing aromatic acyl derivatives of formula (I) using methanesulfonic acid. The invention further relates to methods for preparing biological active ingredients, such as paracetamol.
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WO/2023/072998A1 |
The present invention relates to an improved method for preparing and isolating hydrogen cyanide, said method comprising the reaction of methane (e.g. natural gas), ammonia and optionally oxygen, wherein C2-C10 nitrile by-products, such ...
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WO/2023/061101A1 |
Disclosed are an HDAC/MAO-B dual inhibitor, the preparation thereof, and an application in the preparation of a drug and neuroprotective antioxidant for preventing and treating related diseases by inhibiting monoamine oxidase and histone...
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WO/2023/063466A1 |
Disclosed is a method for preparing a ceramide compound. Specifically, provided is a method for synthesizing ceramide by reaction of phytosphingosine and a methyl ester-based compound represented by chemical formula 2, as starting materi...
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WO/2023/060955A1 |
Provided in the present invention is a synthetic method for cetyl-PG hydroxyethyl palmitamide. The method comprises the following steps: firstly, mixing 1,3-dichloropropanol and hexadecyl alcohol under the action of a catalyst and an alk...
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WO/2023/056957A1 |
A solvent system of a working solution for producing hydrogen peroxide by means of an anthraquinone method. The solvent system comprises the following components or are composed of the following components in parts by volume: A) 2-60 par...
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WO/2023/054350A1 |
The present invention provides a production method for purified dichloroacetic acid and an efficient production method for nucleic acid molecules using same. Specifically, the present invention provides: a production method for purified ...
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WO/2023/053877A1 |
Provided are: a compound suitable for use as a photodisintegrable base for resist compositions which have satisfactory sensitivity to actinic energy, e.g., EB or EUV, have excellent resolution in lithography, and can give fine patterns r...
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WO/2023/055050A1 |
The present invention relates to: a method for removing a compound of chemical formula 1, comprising the step of adding a metal hydroxide compound to a composition comprising chemical formula 1 and a water-soluble solvent; and a method f...
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WO/2023/045371A1 |
Disclosed is a novel cationic lipid compound represented by formula (A), or an isomer, an N-oxide, a pharmaceutically acceptable salt, or a prodrug thereof. Further disclosed are a preparation method, a composition and an application of ...
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