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Matches 301 - 350 out of 4,771

Document Document Title
WO/1986/003196A1
Methyl substituted bicyclo AD2.2.1 BDheptan nitriles of the general formula (A), wherein the methyl group occupies the position C-4 or C-5, the residue R1 is at C-2 and the nitrile group is at C-3 or alternately the residue R1 is at C-3 ...  
WO/1986/003191A1
Methyl substituted bicyclo AD2.2.1 BD heptane/heptene methylol derivatives of general formula (A), wherein the methyl group occupies the position C-4 or C-5, the residue R1 the position C-2 and the methylol residue the position C-3 or al...  
WO/1986/001812A1
Chlorine-containing thermoplasts are disclosed which contain as stabilizer at least one compound of formula (I) wherein m is 0, 1 or 2, n is 1, 2 or 3 and P = 1 or 2, Y represents -F, -Cl, -Br, -I, -CH3 or C2H5, X represents -NH2, -NHCH3...  
WO/1986/001201A1
o-Aminomethylphenol compounds represented by general formula (I), (wherein X represents hydrogen or halogen, R represents hydrogen or C1-4 alkyl, A represents C1-4 alkyl, phenyl, benzyl or a bifunctional chain of -(CH2)3- or -O(CH2)2- bo...  
WO/1986/000887A1
Quinone derivatives represented by general formula (I) wherein R1 and R2 may be the same or different, and each represents hydrogen, methyl or methoxy or, when taken together, R1 and R2 represent -CH=CH-CH=CH-, R3 represents hydrogen or ...  
WO/1985/000366A1
Compounds having the formula (I) wherein R1 and R2 are a hydrogen atom, an alkyl group or a hydroxy group, or else R1 and R2 form together a bivalent ethylene or trimethylene radical; R3 is a halogen atom, an alkyl group, an alkoxy group...  
WO/1984/004676A1
Polyhydroxybenzo-, polyhydroxyphenylaceto-, and polyhydroxymandelo-substituted amidines, amidates, amidoximes, and hydroxyamidoximes, also polyhydroxybenzonitriles and polyhydroxybenzamides; their syntheses, pharmaceutical formulation an...  
WO/1984/004247A1
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods fo...  
WO/1984/004245A1
A class of naphthalene aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the tr...  
WO/1984/003883A1
A C-substituted or unsubstituted aryl-N-substituted or unsubstituted (branched alkyl or cycloalkyl) nitrone having anti-fatigue and/or antiozonant properties in rubber.  
WO/1984/003088A1
New nitrosoureas, their preparation and application in therapy, consisting of compounds having the formula (I), of the series L, D, DL, allo and threo, wherein: A represents the fragment of an amino acid having the formula HN(R)-A-COOH, ...  
WO/1984/002844A1
Utilisation as antibacterial medicaments of halogenobenzophenone-oxime derivatives having the formula (I), wherein R is a branched hydrocarbonated chain C3-C8 alkyl group, and Ar is a halogenophenyl group having the formula (II), wherein...  
WO/1984/000875A1
Methods for the treatment of physiological disorders, including protozoal infections in mammalian and avian species and gastrointestinal and cardiovascular disorders in mammalian species by administering a class of aralkyl- and aralkenyl...  
WO/1983/003604A1
Process for preparing substitued polycyclo-alkylidene polycyclo-alkanes, such as substituted adamantylidene adamantanes, and the corresponding epidioxy compounds, in which polycyclo-alkylidene polycyclo-alkanes are halogenated with an N-...  
WO/1983/002273A1
Novel compounds have a formula (I)$(10,)$wherein$(6,)$represents a bicyclo AD2,2,1 BD hept-2Z-ene, bicyclo AD2,2,1 BD heptane, 7-oxa-bicyclo AD2,2,1 BD hept-2Z-ene, 7-oxa-bicyclo AD2,2,1 BD heptane, bicyclo AD 2,2,2 BD oct-2Z-ene or bicy...  
WO/1983/001773A1
Stabilized pesticide compositions for use particularly as insecticides comprise gallic acid or the propyl ester thereof in combination with an oxime carbamate of the formula$(8,)$wherein R1 can be R2-R4 or X; R2-R4 can be H, lower alkyl,...  
WO/1983/001772A1
Compounds of the formula$(10,)$wherein R1 is lower alkyl, lower cycloalkyl, lower alkenyl, lower alkynyl, lower alkyl carboxymethyl, aryl carboxymethyl, aryl, or aralkyl; A is a direct bond, lower alkylene, or lower alkenylene; x is 1 or...  
WO/1983/001770A1
Novel compounds of the general formula$(10,)$wherein Ar represents a substituted or unsubstituted aromatic or heterocyclic group; W represents alkylene of from 1 to about 10 carbon atoms; and B represents -NR2COR1, -NR2CONR1R3, -NR2SO2R1...  
WO/1983/000861A1
A process for the preparation of urea from ammonia and carbon dioxide at an elevated temperature and pressure having a reaction zone and a stripping zone. In the reaction zone, carbon dioxide and a portion of the ammonia are converted to...  
WO/1983/000862A1
A process for the preparation of urea from ammonia and carbon dioxide at an elevated temperature and pressure having a reaction zone and a stripping zone. In the reaction zone, carbon dioxide and a portion of the ammonia are converted to...  
WO/1983/000860A1
Compounds having the formula:$(6,)$wherein:$(8,)$R4 = -OCH3, -NH2, NH-R4, R4 being an oligopeptidic residue of which the terminal carboxyl group is blocked as a methyl ester or amide group. They are prepared by reacting the corresponding...  
WO/1983/000328A1
Novel adducts are prepared from 1,4-cyclohexane bis(methylisocyanate), which may be substituted in the cyclohexane ring, and active hydrogen-containing compounds, such as phenols, lactams, oximes, and alkyl acylacetates and alkoxycarbony...  
WO/1982/004042A1
Compounds of the formula (FORMULA) wherein Y is OH, R4COO, (R5)2 NCOO or R6O, whereby R4 is an alkyl group having 1-5 carbon atoms or a possibly substituted phenyl group, R5 is an alkyl group having 1-5 carbon atoms and R6 is an allyl or...  
WO/1982/001367A1
Guanidine derivatives of formula: (FORMULA) their isomers at the guanidine groups and pharmaceutically acceptable salts of such compounds, wherein one of X and Y is CR5 and the other is CH or N; R1 is hydrogen, halogen, nitro, amino, NHC...  
WO/1982/000823A1
3,6-bis(carboethoxyamino)-2,5-diaziridinyl-1,4-benzoquinone, sometimes known as "AZQ" is prepared by reacting a dialkylpyrocarbonate with a diamino hydroquinone to form 2,5-dichloro-3,6-bis (carboethoxyamino)-1,4-hydroquinone. The latte...  
WO/1981/000849A1
Novel process and novel intermediates useful in the preparation of sympathomimetic amines. The pharmacologically useful final products, which are acyl derivatives of mono- and dihydroxy aromatic amines (e.g., catechol amines) can be prep...  
WO/1980/002686A1
A process for preparing aromatic urethane by reacting an aromatic nitro compound, a hydroxy group-containing organic compound having at least one hydroxy group, and carbon monoxide at elevated temperatures under high pressure in the pres...  
WO/1980/002424A1
Anthracene-9,10-bis-carbonyl-hydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or palliation of leukemia and related cancers.  
WO/1980/002425A1
A process for concentrating an aqueous urea solution, which comprises concentrating an aqueous urea solution having a concentration of, preferably, 70-90 wt.% under vacuum to a concentration of 95-99 wt.%, and contacting the thus obtaine...  
WO/1980/001800A1
Method for eliminating aromatic amines from the waste water by way of introducing aromatic mono- or poly-isocyantes at a molar ratio of 1: 1 (Alpha) 30 and separation of the resulting sediment. The aromatic isocyantes are introduced in a...  
WO/1980/001694A1
Cyano-guanidins having the formula: (FORMULA) wherein: R1 is (a) the remains HS-CH2-CH2-, (b) the remains HO-CH2-CH2-, (c) the remains (FORMULA) (d) the remains (FORMULA) and several processes of the respective preparation thereof. The c...  
WO/1980/001382A1
Novel bicyclo (2,2,1) heptanes and hept-2-enes are substituted at the 5-position by a 6-carboxyhex-2-enyl group or a modification thereof, and at the 6-position by a grouping -C(R)=N-NHCO-(NH)a-R' in which R is hydrogen, an aliphatic hyd...  
WO/1980/000343A1
This method of synthesizing urea comprises the steps of introducing into a first heater (3) the distillate of a reactor (2) containing urea, ammonium carbonate, excess ammonia and water, separating the excess ammonia and decomposing the ...  
WO/1980/000344A1
New herbicide N-trifluoromethyl-3 ethyl-4 phenyl N' N' dimethylurea is appropriate for use as active herbicide material. It is appropriate for selective weed-killing of crops (cereals, corn, cotton, soya bean).  
WO/1980/000151A1
Compounds of the formula: (FORMULA) wherein: Y is 2,6-dimethylphenyl, 2,5-dimethylphenyl, 5-bromo-2-methylphenyl, or 5-chloro-2-methylphenyl; and X is propyl, isopropyl, n-butyl, or isobutyl; or a non-toxic, pharmaceutically acceptable a...  
WO/1980/000023A1
Compounds of formula: (FORMULA) wherein R1 is an optionally substituted alkoxy, alkanyloxy, phenoxy, alkylthio, phenylthio or amino group and R2 is a chloro and/or trifluoromethyl-substituted phenyl or phenoxyphenyl group. A typical exam...  
JP2022554054A
The present invention relates to compounds and compositions containing them for use in the prevention and/or treatment of non-alcoholic fatty liver disease (NAFLD), in particular fatty liver or non-alcoholic steatohepatitis (NASH).  
JP2022184336A
[PROBLEMS] To provide a novel branched glycerol derivative, a coating agent containing the branched glycerol derivative as an active ingredient, and capable of coating the surface of a substrate in order to impart antifogging properties,...  
JP2022548749A
The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging and therapeutic agents when conjugated to a suitable metal center, particularly for tumor imaging.  
JP7169584B2
To provide a novel compound having an auxin biosynthesis inhibitory activity, and a novel compound having the auxin biosynthesis inhibitory activity with different mechanism of action from conventional auxin biosynthesis inhibitors.An as...  
JP7157462B2
This disclosure is related to aromatic compounds of formula (I), and methods of their use in treating medical conditions associated with Heat Shock Protein-90 (HSP90), e.g., cancer. Compounds of formula (I) have the following structure:A...  
JP7075669B2
The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their int...  
JP2022526450A
Disclosed herein are compounds that regulate the interaction of CD-40-CD40L, including pharmaceutically acceptable salts, esters, prodrugs, hydrates and mutants thereof. be. These compounds are useful in treating, ameliorating, or preven...  
JP2022517902A
The present invention provides amides that inhibit cell necrosis, corresponding sulfonamides and prodrugs, as well as pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compound of the present invention is used in...  
JP2022513588A
The present invention relates to a novel process for iridium-catalyzed hydrogenation of oxime. The present invention also relates to novel iridium catalysts used in oxime iridium-catalyzed hydrogenation and the process of preparing these...  
JP2022512919A
The present invention relates to a novel process for enantioselective iridium-catalyzed hydrogenation of oximes and oxime ethers to obtain compounds of formula (II) and salts thereof formulas (I) and (II).  
JP7001597B2
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new c...  
JP2021534215A
The invention includes novel aromatic molecules that can be used to treat pathological conditions such as cancer, skin disorders, muscle disorders and immune system related disorders, such as disorders of the hematopoietic system, includ...  
JP6968633B2
The present invention provides a photosensitive composition which suppresses adhesion after curing and has excellent curing properties, and a compound and a photopolymerization initiator used therefor. The photosensitive composition of t...  
JP2021155381A
To provide a method for efficiently producing an O-substituted hydroxylamine derivative useful as an active ingredient of an aldehyde scavenger.A method for producing an O-substituted hydroxylamine derivative (1) includes hydrolyzing 2-[...  

Matches 301 - 350 out of 4,771