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WO/2014/099610A1 |
Described is a process for the integrated production of hexamethylenediamine. The process includes integrating an HCN production process, a dinitrile compound production process, and a diamine production process. The HCN production proce...
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WO/2014/089303A1 |
The invention provides methods useful in the industrial scale process for hydrocyanation of butadiene to adiponitrile for recycle of unwanted byproduct 2-methyl-3-butenenitrile (2M3BN) by conversion to process intermediate pentenenitrile...
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WO/2014/089347A1 |
Disclosed is a process for isomerizing cis-2-pentenenitrile to 3-pentenenitrile in the presence of a non-aluminium metal oxide catalyst, wherein: (a) the metal in the catalyst has an oxidation state in the range from +1 to +4; (b) the me...
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WO/2014/089343A1 |
Pentenenitrile oligomers formed in a process for isomerizing cis-2-pentenenitrile to 3-pentenenitrile are minimized in the presence of an aluminium oxide catalyst. The process comprises providing an aluminium oxide catalyst having an alk...
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WO/2014/089492A1 |
In the hydrocyanation reaction of butadiene proceeding through pentenenitriles to adiponitrile, catalysis by complexes of zerovalent nickel with bidentate phosphorus-based ligands of the NiL2A type wherein L2 is a bidentate ligand and A ...
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WO/2014/087105A1 |
Process for synthesis of the compound of formula (I): application to the synthesis of ivabradine, and of addition salts thereof with a pharmaceutically acceptable acid and of hydrates thereof.
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WO/2014/082022A1 |
A process for preparation of catalysts for the production of acrylonitrile, acetonitrile and hydrogen cyanide comprising contacting at an elevated temperature, propylene, ammonia and oxygen in the vapor phase in the presence of a catalys...
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WO/2014/073672A1 |
This method for producing an aldehyde compound comprises a step for reacting a compound represented by general formula (a1) or general formula (a2) with hydrogen and carbon monoxide in the presence of a phosphorus compound and a metal co...
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WO/2014/072640A1 |
A method for synthesising the compound of formula (I): Application to the synthesis of ivabradine, the addition salts of same with a pharmaceutically acceptable acid, and the hydrates thereof.
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WO/2014/073664A1 |
This method for producing an aldehyde compound comprises a step for reacting a compound represented by general formula (a1) with hydrogen and carbon monoxide in the presence of a phosphorus compound and a metal compound that contains 0.0...
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WO/2014/073663A1 |
This method for purifying an aldehyde compound comprises: a step for neutralizing a reaction solution, which contains an aldehyde compound that is obtained by reacting a compound represented by general formula (a1) or (a2) with hydrogen ...
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WO/2014/072641A1 |
The invention concerns a method for the selective extraction of a reaction product, originating from an oxidative cleavage of an unsaturated fatty acid or of an ester derivative or of an unsaturated nitrile derivative, said reaction prod...
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WO/2014/073003A1 |
The present invention relates to the single-step process for the synthesis of aryl olefin compounds of Formula (1) by reacting aryl aldehydes with alkyl aldehydes in presence of malononitrile and acid or base or salt, optionally in prese...
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WO/2014/000629A9 |
The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in g...
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WO/2014/062428A1 |
This invention provides a method for the synthesis of a 2-amino-4,6-dimethoxybenzamide and other benzamides of Compound I: wherein R1, R2, R3, and R4 each independently represent a hydrogen, a C1-C6 alkyl, or a C1-C6 alkoxy; and wherein ...
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WO/2014/056421A1 |
Provided are a 1-cyan-1-(7-methoxyl-1-naphtyl) methanol ester compound, and preparation method and use thereof in the preparation of agomelatine intermediate 2-(7-methoxyl-1-naphtyl) ethylamine. Also provided is an agomelatine preparatio...
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WO/2014/057228A1 |
A method for synthesising the compound of formula (I): Application to the synthesis of ivabradine, the addition salts thereof with a pharmaceutically acceptable acid, and the hydrates thereof.
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WO/2014/054408A1 |
The purpose of the present invention is to provide a method for safely and quickly stopping ammoxidation without reducing catalytic activity or the acrylonitrile yield in the case of stopping ammoxidation of propane. Provided is a method...
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WO/2014/051090A1 |
The purpose of the present invention is to provide: an oxide catalyst which is suppressed in reduction degradation of the catalyst even in a long time industrial operation, while being small in decrease of the yield of an unsaturated ald...
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WO/2014/050272A1 |
The present invention mainly addresses the problem of providing a method for producing a complex composed of an organic nitrogen compound and a copper (I) salt of a fluorooxo acid with high yield while reducing the corrosion of a reactio...
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WO/2014/050615A1 |
This composite oxide catalyst is used for a vapor-phase catalytic oxidation reaction or vapor-phase catalytic ammoxidation reaction of propane or isobutane, and contains a composite oxide that is represented by a composition formula Mo1V...
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WO/2014/034500A1 |
This method for purifying acetonitrile comprises: a step for obtaining a reaction liquid by supplying an alkali and crude acetonitrile, which has been obtained by an ammoxidation reaction, into a reaction tank; a step for obtaining a liq...
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WO/2014/031226A1 |
Methods and systems are provided for converting methane in a feed stream to acetylene. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor ef...
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WO/2014/012467A1 |
Provided is a diarylaniline or diarylpyridinamine compound and the preparation method and use thereof for preparing a drug. The compound has strong inhibition activity against wild-type and various resistant HIV viral strains (nM level) ...
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WO/2014/014620A1 |
The present invention relates to reduction of corrosion. The present invention includes a method of decreasing corrosion during ammonia extraction. The method includes performing a process to extract ammonia using ammonia extraction equi...
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WO/2014/012466A1 |
Provided are compounds of diarylanilines and diarylpyridinamines, a preparation method therefor, and uses thereof. The compounds have strong inhibitory activity (nM level) for a wild-type and multiple drug-resistant HIV strains, have goo...
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WO/2014/013261A1 |
The present invention provides a use of Iithium amide in liquid ammonia as a base to produce an enolate from at least one ester starting material in a crossed Claisen condensation reaction, wherein at least one ester starting material is...
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WO/2014/013151A1 |
The present invention relates to a method for manufacturing diaminomaleonitrile, characterised in that said method includes at least one step during which a cyanohydrin ketone with formula RR'COHCN, R and R', which are the same or differ...
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WO/2013/093943A9 |
Disclosed herein is a single step catalytic process for the production of enantiomerically pure α-Aryloxy-α'-Azido/Alkoxy alcohols of formula (A). The invention, in particular discloses phenolytic kinetic resolution of racemic anti and...
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WO/2014/005134A2 |
The present teachings provide a compound of Formula (I-B): wherein R1-R10 are as described herein; a pharmaceutically acceptable salt of the compound, a geometric isomer of the compound, or a pharmaceutically acceptable salt of the geome...
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WO/2013/182345A1 |
An amine according to the invention has a formula (CH3)2NCH2CH2OCH2CH2CH2N(R1)(R2) wherein R1 is selected from (CH3)2NCH2CH2OCH2CH2CH2- and R2 is selected from the group consisting of H-, CH3(CnH2n)-,HO(CmH2m)- and (CH3)2NCH2CH2OCH2CH2CH...
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WO/2013/181096A1 |
The invention provides a method of forming a phosphonate diester compound from a ligand hydrolysis product (LHP) of a phosphite ligand used in a nickel-phosphite hydrocyanation catalyst, such as for conversion of 3-pentenenitrile to adip...
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WO/2013/176421A1 |
The present invention relates to: a method for preparing a tricyanoalkoxyalkane compound, and more specifically, to a nonaqueous electrolyte solution for a lithium secondary battery, comprising a tricyanoalkoxyalkane compound prepared by...
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WO/2013/176088A1 |
The present invention provides a method for producing a nitrile represented by general formula (1) (in the formula, R denotes an optionally substituted alkyl group, alkenyl group, dienyl group, aralkyl group or aryl group having a total ...
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WO/2013/160229A1 |
The present invention relates to an improved process for batchwise or continuous isomerization of cis-2-pentenenitrile to 3-pentenenitriles in the presence of 1,4-diazabicyclo[2.2.2]octane as a catalyst.
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WO/2013/149566A1 |
Provided herein are processes for preparing a compound of Formula (V), comprising nitrating a compound of Formula (IV), with a nitrating agent in the presence of a catalyst.
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WO/2013/149364A1 |
Disclosed in the present invention is a method for synthesizing 1-hydroxymethyl cyclopropyl acetonitrile, comprising firstly using a compound of tribromo-neopentyl alcohol 1 as a starting raw material and acetylating tribromo-neopentyl a...
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WO/2013/146609A1 |
A method for purifying acetonitrile, said method comprising steps for adding an alkali to water-containing acetonitrile that has been produced by an ammoxidation reaction, reacting the alkali therewith, supplying the resulting reaction m...
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WO/2013/132520A1 |
The present invention discloses a cheaper and practical protocol for the construction of a wide variety of o-cyanocinnamonitrile and their structural analogues that proceeds with good yields in a single step using CuCN as the only reagent.
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WO/2013/132006A1 |
The present invention describes a method for synthesising 2-aminobiphenyls and derivatives thereof. This method can be performed cost-effectively and is based on selective reactions. Functionalised biphenyl compounds are of great interes...
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WO/2013/129385A1 |
The present invention relates to a method for producing acrylonitrile, the method comprising a gas-phase catalytic ammoxidation step for obtaining acrylonitrile by bringing a starting gas comprising propylene, molecular oxygen, and ammon...
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WO/2013/129424A1 |
The present invention pertains to a method that is for producing acrylonitrile and that is characterized by containing a gas-phase contact ammoxidation step for performing gas-phase contact ammoxidation by causing a starting material gas...
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WO/2013/129363A1 |
This method for producing acrylonitrile is characterized by including a gas-phase contact ammoxidation step for causing a starting material gas containing propylene, molecular oxygen, and ammonia to contact a fluidized bed catalyst to ca...
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WO/2013/130436A1 |
The present invention relates to processes for preparing 3-methylsulfonylpropionitrile. The processes provide a good yield and a good purity of the final product and provide a controllable reaction. The present invention also relates to ...
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WO/2013/125639A1 |
The purpose of the present invention is to effectively reduce deposits of molybdenum oxides on a contact surface with which a molybdenum compound freed from a metal oxide catalyst makes contact in a gas phase reaction device for carrying...
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WO/2013/124280A1 |
The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
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WO/2013/121018A1 |
Provided is a process for obtaining a compound of formula (I): N≡C-CH2-A-C(O)-OR, wherein Hal is halogen selected from F, Cl, Br or I, A denotes a bond or a divalent spacer selected from alkylene and arylene groups, and R is a C1-4 alk...
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WO/2013/121151A1 |
The present invention relates to a process for producing dinitrile, characterized in that it comprises at least one step of reaction between a sodium disalt of a diacid and an ammonia source, under the following conditions: - the ammonia...
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WO/2013/120808A1 |
The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising ...
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WO/2013/120805A1 |
The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising ...
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