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Patent Searching and Data


Matches 401 - 450 out of 1,843

Document Document Title
WO/1999/029670A2
The present invention relates to bicyclene of general formula (I) substituted by an aminocarbonyl radical, wherein R¿1?-R¿6?, X¿1?-X¿3?, Y¿1?-Y¿2? are defined as in claim 1 and the tautomers, stereoisomers, mixtures and salts there...  
WO/1999/028284A1
The invention referres to dibenzosuberone derivatives and to the procedures of their preparation. According to this invention, conditions for a regioselective bromination of dibenzosuberone have been found, as well as for the isolation o...  
WO/1999/026919A1
Biphenylamidine derivatives represented by general formula (1) or pharmaceutically acceptable salts thereof, both being novel compounds functioning as clinically applicable Fxa inhibitors.  
WO/1999/026918A1
Biphenylamidine derivatives represented by general formula (1) or pharmaceutically acceptable salts thereof, both being novel compounds functioning as clinically applicable Fxa inhibitors.  
WO1999005096A3
Compounds having formula (I) are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions and a method of inhibiting urokinase in a mammal.  
WO/1999/024407A1
The present invention is directed to compounds which are capable of inhibiting the activity of tryptase. Such compounds are useful in the treatment or prevention of inflammatory disease, particularly those disease states which are mediat...  
WO/1999/024395A1
The present invention is directed to compounds which are capable of inhibiting the activity of tryptase. Such compounds are useful in the treatment or prevention of inflammatory disease, particularly those disease states which are mediat...  
WO/1999/022707A1
The invention concerns a composition for topical application on the skin and/or its appendages comprising, in a cosmetically and/or dermatologically acceptable medium, at least a compound containing an iminophenol fragment, and the use o...  
WO/1999/010316A1
3-Amidinoaniline derivatives represented by general formula (I) which have potent and selective activity of inhibiting activated blood coagulation factor X and are useful as activated blood coagulation factor X inhibitors, or pharmacolog...  
WO1998045259A3
The present invention relates to polyaromatic compounds having useful antiviral activity against viruses of the herpes family, to a composition containing them, and to a method of using them for the treatment of herpes viruses infections.  
WO1998040420A3  
WO/1999/005096A2
Compounds having formula (I) are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions and a method of inhibiting urokinase in a mammal.  
WO/1999/004778A1
The present invention provides novel indane-like compounds which can be useful for treating psychosis and other conditions associated with the modulation of a muscarinic receptor. The invention provides formulations and methods for using...  
WO/1999/000127A1
This application relates to a compound of formula (I) (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of ...  
WO/1999/000356A1
This invention relates to compounds of formula (I) which inhibit Factor Xa, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of patients suffering from conditions which can be ame...  
WO/1999/000121A1
This application relates to a compound of formula (I) (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of ...  
WO/1998/058905A1
Amidrazone derivatives of formula (I) useful for prevention or treatment of lupus mycosis attributable to fungi, such as Candida, Aspergillus, and Cryptococcus, pharmaceutically acceptable salts thereof, and pharmaceutical compositions t...  
WO1998040374A3  
WO/1998/050344A1
Substituted cyanoenamines of general formula (I) wherein Z, R?1�, R?2� and R?3� are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment o...  
WO/1998/047933A1
Provided are certain transition metal complexes which are useful as catalysts in the polymerization of olefinic monomers. In particular, the invention provides complexes of certain bidentate ligands bonded to Ni, Pd, Co, or Fe, and optio...  
WO/1998/047894A1
3-(Substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and ...  
WO/1998/045259A2
The present invention relates to polyaromatic compounds having useful antiviral activity against viruses of the herpes family, to a composition containing them, and to a method of using them for the treatment of herpes viruses infections.  
WO/1998/043973A1
The invention relates to a new method for the production of a compound having formula (I) or one of its salts. In this formula, the radicals have the meanings given in the description. This method relates to a new intermediary compound h...  
WO1998029358A3
Battery has an electrolyte comprising a solvent and a salt (I) comprising a hydroxonium, nitrosonium, ammonium, metal, organic or organometallic cation and a 5-membered (hetero)cyclic anion. Battery has an electrolyte comprising a solven...  
WO/1998/040370A1
The present invention provides compounds having the structure: Ar�1?-Q-Ar�2?-O-(CH�2?)�n?-Z and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are media...  
WO/1998/040420A2
The present invention includes novel ligands which may be utilized as part of a catalyst system. A catalyst system of the present invention is a transition metal-ligand complex. In particular, the catalyst system includes a transition me...  
WO/1998/040374A2
Methods for preparing olefin polymers, or oligomers catalysts for preparing olefin polymers and bidentate ligand used for preparing these catalysts are disclosed. The polymers can be prepared containing the corresponding monomers with a ...  
WO/1998/034898A1
The invention relates to phenoxyacetic acid derivatives of formula (I), wherein R�1?, R�2?, Xn and A are as defined in the description, A represents a halogen atom, hydroxy, OR�3?, S(O)�k?R�3?, or a group of formula (A-1) or (A...  
WO/1998/031661A1
Benzamidine derivatives involving compounds represented by formulae (a) and (b) and analogs thereof or pharmaceutically acceptable salts thereof. These compounds show anticoagulant effects based on their excellent effects of inhibiting a...  
WO1998017626A3  
WO/1998/031660A1
The present invention provides novel indane-like compounds which can be useful for treating conditions associated with the modulation of a muscarinic receptor. The invention provides novel processes and intermediates for preparing the no...  
WO1998015512A3
The invention concerns fungicidal compounds, and compositions containing them, of general formula (I) in which G is selected from the groups G1 to G9: (a) in which the different symbols represent various organic groups. The invention als...  
WO/1998/029399A1
The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M?+m� in sufficient numbers to ensur...  
WO/1998/029388A1
The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic...  
WO/1998/029384A1
The invention concerns 2-benzoyl-cyclohexan-1,3-diones of formula (I), in which R?1�, R?2� stand for hydrogen, nitro, halogen, cyano, rhodano, alkyl, halogen alkyl, alkoxyalkyl, alkenyl, alkinyl, -OR?5�, -OCOR?6�, -OSO�2?R?6�...  
WO/1998/029877A1
Disclosed is a proton conductor in liquid form, comprised of a mixture of the following components: (a) a salt combined with a nitrogenated base along with an acid, according to formula (I), wherein Z�1?, Z�2?, Z�3?, and Z�4?, wh...  
WO/1998/029389A1
The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion...  
WO/1998/029396A1
The invention relates to ionic compounds in which the anionic load has been displaced, and the uses of these compounds. A compound disclosed by the invention comprises an anionic portion combined with at least one cationic portion M?+m...  
WO/1998/029358A2
Disclosed is a method for grafting a polymer onto the surface of a carbonate material with carboxyl, amine, and/or hydroxyl functions on its surface. Said material is placed in suspension in a solution including the polymer to be grafted...  
WO1998006691A3  
WO/1998/017626A2
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural ...  
WO/1998/016506A1
The present invention relates to the discovery of novel, low molecular weight, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stromelysins and collagenases) and TNF-$g(a) converting enzyme (TACE, tumor necrosis fa...  
WO/1998/015512A2
The invention concerns fungicidal compounds, and compositions containing them, of general formula (I) in which G is selected from the groups G1 to G9: (a) in which the different symbols represent various organic groups. The invention als...  
WO/1998/010763A1
A compound which inhibits human thrombin and which has general structure (I) such as formula (a).  
WO/1998/011062A1
The current invention relates to new benzamidine derivatives, a process for the manufacture and the use thereof as medicaments. The new benzamidine derivatives have the general formula (1).  
WO/1998/009950A1
The invention concerns a process for preparing amidines and their salts with inorganic or organic acids. According to this process, the corresponding nitrile is reacted with ammonia, a C�1?-C�6? alkylamine or hydrazine in the presenc...  
WO/1998/008799A1
The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glyc...  
WO/1998/006691A2
Low molecular weight dendritic polymers (dendroids) of Formula (I) or a pharmaceutically acceptable salt thereof wherein A is selected from 1,2,3,5-tetrasubstituted or 1,2,4- or 1,3,5-trisubstituted benzene; 2,3,4,5-tetrasubstituted or 2...  
WO/1998/003475A1
A composition, which comprises at least one compound of formula (I), in which A�1?, A�2?, R�1? and R�2? are as defined in claim 1, or, if appropriate, an E/Z isomer, an E/Z isomer mixture and/or a tautomer thereof, in each case i...  
WO/1998/000427A1
The present invention discloses new processes in the preparation of midazolam (VII), a commercially important pharmaceutical, as well as new intermediates in those processes from a known benzophenone (I) starting material.  

Matches 401 - 450 out of 1,843