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Matches 701 - 750 out of 1,858

Document Document Title
WO/1991/016299A1
A method for control of plant disease, especially fungus, using compounds of formula (I) and novel compounds within the class, wherein: A is C(=O)R, C(=O)OR1, C(=O)SR1, P(=O)QR2Q1R3; C(=O)NHR, SO2R5, SO2NR6R7; Q and Q1 are independently ...  
WO/1991/014674A2
Hydroxyurea compounds comprising substituted and unsubstituted 1,2,3,4-tetrahydronaphthalene, indane, dihydrobenzofuran, 4H-2,3-dihydrobenzopyran, dihydrobenzothiophene, and indoline derivatives, pharmaceutical compositions containing sa...  
WO/1991/012230A1
The present invention relates to novel nitric acid esters of cyclohexanol derivatives of formula (I) in which A is a valency line or a C�1?-C�6? alkylene chain and B is the group -NR?1�-CO-Z, -NR?1�-SO�2?-Z or -CO-NR?2�-Z, wh...  
WO/1991/010645A2
There are provided novel chelating agents useful in the preparation of contrast media for diagnostic imaging or of radiotherapeutic or detoxification compositions.  
WO/1991/008737A2
This invention relates to compounds having pharmacological activity, processes for their preparation, compositions containing them and methods of treatment involving their use. In its broadest aspect, the invention is concerned with comp...  
WO/1991/008191A1
The invention provides compounds, several of which belong to a class having two or more nonpolar components connected by a polar group and having polar groups on the termini of the compound. The invention also concents a method of select...  
WO/1991/005757A1
Novel compounds of formula (1) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Also disclosed are pharmaceutical compositions containing compounds of formula (1). Methods of treating allergy, inflammation and hype...  
WO/1991/002716A2
Compounds of general formula (I) wherein R1 represents a hydrogen atom or a C1-C6 alkyl, C1-C6 alkenyl, phenyl, phenyl(C1-C6)alkyl, C1-C6 alkylthiomethyl, phenylthiomethyl, substituted phenylthiomethyl, phenyl(C1-C6)alkylthiomethyl or he...  
WO/1991/000257A1
The invention provides compounds, several of which belong to a class having two or more nonpolar components connected by a polar group and having polar groups on the termini of the compound. The invention also concerns a method of select...  
WO/1990/012784A1
A method for control of plant disease, especially fungus, using compounds of formula (I) and novel compounds within the class (I), wherein: A is C(=O)R, C(=O)OR?1¿, C(=O)SR?1¿, P(=O)QR?2¿Q?1¿R?3¿; C(=O)NHR, SO¿2?R?5¿, SO¿2?NR?6¿...  
WO/1990/009092A2
The invention provides a class of compounds having two or more nonpolar components connected by a polar group and having polar groups on the termini of the compound. The invention also concerns a method of selectively inducing termini di...  
WO/1990/008131A1
The invention relates to an improved process for preparing amidoxime derivatives of general formula (I), wherein R1 means a C2-15 group, which may be unsaturated and/or cyclic alkyl, aralkyl group or optionally substituted and/or condens...  
WO/1990/008134A1
There are provided chelating agents particularly useful for the preparation of diagnostic and therapeutic agents for magnetic resonance imaging, scintigraphy, ultrasound imaging, radiotherapy and heavy metal detoxification, said agents b...  
WO/1990/007494A1
This invention relates to a new hydroxylamine derivative exhibiting a 5-lipoxygenase inhibitory activity and represented by general formula (I) (wherein R1 stands for aryl, aryloxy, arylthio, aryl(lower)alkyl, or aryl(lower)alkoxy, R2 fo...  
WO/1990/005716A1
Compounds of general formula (I), wherein R1 represents a hydrogen atom or a C1-C6 alkyl, C1-C6 alkenyl, phenyl, phenyl(C1-C6)alkyl, C1-C6 alkylthiomethyl, phenylthiomethyl, substituted phenylthiomethyl, phenyl(C1-C6)alkylthiomethyl or h...  
WO/1990/004584A1
The present invention relates to novel hydroximic acid halides, the preparation of the same, pharmaceutical compositions containing the above novel compounds as active ingredients as well as the use of the said compounds in the therapy o...  
WO/1990/003399A1
Compounds and methods for the treatment and diagnosis of cancer are provided. Also provided are methods for isolating human amino acid transporters or subunits thereof, and substantially purified transporters or subunits. In particular, ...  
WO/1989/006645A1
The present invention includes compounds represented by formula (I), wherein n is 0 or 1; R1, R2, R3 and R4 are independently selected from hydrogen, hydroxyl, amino, alkylamino, alkylsulfonylamino, loweralkyl, loweralkoxy, halo, and thi...  
WO/1989/002891A1
New compounds of formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meaning stated in the description. Enolethers and their salts, their preparation, herbicides containing these compounds as active ingredients, and the use of t...  
WO/1988/004664A2
Novel renin-inhibitory peptides of the formula X-A6-B7-C8-D9-E10-F11, containing C-terminus truncated epoxy or azido or cyano groups or containing a position 10-11 diol and a position 11-12 retro bond. The present invention further provi...  
WO/1988/004291A1
Organo N-hydroxyimidates are prepared by reacting an organonitrile with an organic alcohol and with a hydrogen halide, in the presence of an organic solvent (which may include an excess of the organonitrile reactant), under anhydrous con...  
WO/1987/002980A1
The invention relates to the field of organic chemistry and particularly to a process for the synthesis of alpha-amino nitriles which comprises subjecting an RCN nitrile to the action of a metal reducing agent to form a metal imine, and ...  
WO/1987/000475A1
A method of machining a surface in the interior of a region encompassed by a predetermined closed curve (CCL), by moving a tool (TL) along a cutting passage (PTi) in a predetermined direction (the direction of an arrow A) to carry out th...  
WO/1986/003745A1
O,O',O''-triacyl-desferrioxamine B having the formula (I), wherein Ac1, Ac2 and Ac3 represent independently from each other an acyl rest of a carboxylic acid having between 1 and 24 atoms of carbon, and salts thereof, may be used in the ...  
WO/1986/000887A1
Quinone derivatives represented by general formula (I) wherein R1 and R2 may be the same or different, and each represents hydrogen, methyl or methoxy or, when taken together, R1 and R2 represent -CH=CH-CH=CH-, R3 represents hydrogen or ...  
WO/1985/003290A1
Compounds of general formula (I), wherein: R1 is acyl of the formula -C(=O)-R5; R2, R3, R4, R6, R7 and R8 are each selected from the group consisting of hydrogen and acyl of the formula: -C(=O)-R5, wherein R5 is selected from the group c...  
WO/1984/004676A1
Polyhydroxybenzo-, polyhydroxyphenylaceto-, and polyhydroxymandelo-substituted amidines, amidates, amidoximes, and hydroxyamidoximes, also polyhydroxybenzonitriles and polyhydroxybenzamides; their syntheses, pharmaceutical formulation an...  
JP2024507822A
The present disclosure discloses a) an essentially pure form of N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo -phenylamino)-benzamide; Crystalline composition of IV, b) essentially of N-((R)-2,3-dihydroxypropoxy)-3,4-diflu...  
JP7406264B2
Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating diseases or disorders in a subject where the subject...  
JP7405903B2
The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).  
JP2023129525A
To provide a novel hydroxamic acid derivative as an inhibitor of meprin β and/or α, a pharmaceutical composition comprising such a compound, a method for treatment or prophylaxis of disease or a condition, especially such that are rela...  
JP2023529011A
Provided herein are indene compounds, eg, compounds of formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use to treat, prevent, or ameliorate one or more symptoms of fibrotic disease. [Chemic...  
JP7296948B2
The present disclosure provides a benzene fused heterocyclic derivative of Formula (I): is a single or double bond; n is an integer of 0 or 1; A is —CH2—, —CH(OH)—, or —C(O)—; G is C or N; X is —CH2—, O, or —C(O)—; Y ...  
JP2023514787A
The present invention relates to compounds of formula (I) and their use as herbicides. In the above formula, R1~R9represents a group such as hydrogen, halogen or an organic group such as alkyl, alkenyl, alkynyl or alkoxy, X is a bond or ...  
JP2023025088A
To provide radiolabeled compounds useful as a radiotracer for positron emission tomography imaging of HDAC, and provide methods for preparing unlabeled and labeled compounds, diagnostic methods, and methods of treating diseases associate...  
JP2023021468A
To provide novel lipids for intracellular delivery of therapeutic agents and compositions involving the same.Nanoparticle compositions in the present disclosure include a novel lipid as well as additional lipids such as phospholipids, st...  
JP2023503330A
FIELD OF THE DISCLOSURE The present disclosure relates generally to cannabinoid derivatives having structural formula (I), pharmaceutical compositions containing them, and methods of using the present cannabinoid derivatives. In some emb...  
JP2022551066A
The present disclosure relates to carmabinoid derivatives of Formula (I), wherein R4 or R7 is a carboxamide group, pharmaceutical compositions comprising these compounds, and methods of using the carmabinoid derivatives. These compounds ...  
JP7183178B2
Provided herein are compounds useful for binding to one or more histone deacetylase enzymes (HDACs). The present application further provides radiolabeled compounds useful as a radiotracer for position emission tomography imaging of HDAC...  
JP7179114B2
The present invention relates to novel hydroxamic acid derivatives as inhibitors of meprin β and/or α, pharmaceutical compositions comprising such compounds, methods for treatment or prophylaxis of diseases or conditions, especially su...  
JP2022141920A
To provide compounds that are useful in treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).The invention provides a compound represented by a formula (I) or a stereoisomer, a pharma...  
JP7140748B2
Amide compounds are disclosed. Also disclosed are pharmaceutical compositions comprising the compounds as well as methods of treating neurodegenerative diseases that involve administering the compounds or pharmaceutical compositions to a...  
JP7082445B2
The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).  
JP7068297B2
The present invention relates to pyrimidine hydroxy amide compounds, the use of such compounds in the inhibition of HDAC6, and the use of such compounds in the treatment of various diseases, disorders, or conditions related to HDAC6.  
JP7034941B2
The present disclosure describes novel compounds of the general Formula (I), their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and...  
JP2022516195A
The present invention relates to the technical field of enzyme inhibitors, and more particularly to hydroxamic acid derivatives, as well as methods and uses thereof. The hydroxamic acid group of the hydroxamic acid derivative provided by...  
JP2022028986A
To provide a method for producing a specific C-arylhydroxy glycoxide derivative in an industrially low-cost and efficient manner.The method includes the step for reacting a compound of (II) with a compound of (III-I) or the like, to obta...  
JP7012289B2
Disclosed are compounds of formulae:and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating...  
JP6953660B2
A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to ob...  
JP6923539B2
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing suc...  

Matches 701 - 750 out of 1,858