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Matches 901 - 950 out of 6,256

Document Document Title
WO/2002/098849A2
Disclosed are compounds of formula X, where R¿n?, R¿20?, R¿1?, R¿2?, R¿3?, and R¿c? are defined herein. These compounds are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising c...  
WO/2002/096864A1
The invention relates to carboxamide-substituted phenylurea derivatives and method for production thereof as medicaments, physiologically-acceptable salts and physiologically-functional derivatives thereof. Compounds of formula (I), in w...  
WO/2002/096884A2
The invention relates to novel substituted benzoylketones of formula (I), in which Q = O (oxygen) or S (sulphur), R?1¿ - R?5¿ and Z have the meaning given in the description and several methods for production thereof and use thereof as...  
WO/2002/096863A1
The present invention relates to certain phenalkyloxy-phenyl derivatives of formula (I) and analogs, to a process for preparing such compounds, having the utility in clinical conditions associated with insulin resistance, to methods for ...  
WO/2002/096876A1
Disclosed are novel aromatic compounds of the formula (I) described herein, wherein G, E, W, Ar, X, Y and Z are disclosed herein. The compounds are useful for treating cytokine mediated diseases or conditions such as chronic inflammatory...  
WO/2002/092574A1
The invention relates to novel substituted benzoylcyclohexenones of formula (I), in which Q, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, Y and Z are defined as per the description. The invention also relates to a method for their production and t...  
WO2002038534A3
The invention relates to novel compounds which are substituted alkyldiamino derivatives of formula (I). The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions con...  
WO/2002/090336A1
The invention relates to novel arylketones of formula (I) wherein A?1¿, A?2¿, Q, R?1¿, R?2¿, X, Y and Z have the meaning cited in the description, the use thereof as herbicides and to methods and intermediate products for the product...  
WO/2002/085838A1
The present invention relaters to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the ...  
WO/2002/085829A1
A process for production of dimers of aromatic monohydroxyl compounds, characterized by conducting the oxidative coupling of an aromatic compound represented by the general formula [I]: Ar-OH [I] (wherein Ar is an optionally substituted ...  
WO/2002/085836A1
A binaphtol derivative represented by the following general formula [1]: [1] and a salt of the derivative.  
WO2001070675A3
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell pr...  
WO2001058855A9
Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. T...  
WO/2002/083627A2
The invention relates to the novel biphenyl derivatives of the general formula (I), wherein R1, R1', R1'', R2 and n are defined as in claim 1. The invention also relates to the stereoisomers and the physiologically acceptable salts or so...  
WO2002062763A3
This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.  
WO/2002/078686A1
The invention relates to the use of retinyl carbonates of formula (I), wherein R represents an optionally substituted C¿1?-C¿12? alkyl, C¿6?-C¿12? aryl, C¿7?-C¿13? aralkyl or a group of formula (II), for the cosmetic treatment of t...  
WO/2002/076402A2
The invention provides conjugates of fatty amines and pharmaceutical agents useful in treating cancers, viruses, psychiatric disorders. Compositions, pharmaceutical preparations, and methods of preparations of the fatty amine-pharmaceuti...  
WO/2002/076930A2
Substituted diarylureas, pharmaceutical compositions containing them, and their use for stimulating Fas-mediated apoptosis. The compounds, as single stereoisomers or mixtures of stereoisomers, their pharmaceutically acceptable salts, and...  
WO/2002/076929A1
In one embodiment, this invention provides a novel class of compounds as antagonists of the MCH receptor, methods of preparing such compounds, pharmaceutical compositions containing one or more of the compounds, methods of preparing phar...  
WO2002044126A3
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins. In the compounds of this invention, at least two carbo-or heterocyclic groups are attached ...  
WO/2002/072534A2
The invention relates novel butane acid derivatives containing a cyanide group, pharmaceutical compositions containing butane acid derivatives and the use of said butane acid derivatives in the production of pharmaceutical compositions f...  
WO2002053534A8
Compounds represented by the general formula (I) or salts thereof, and medicines containing the same: (I) [wherein W is W-A<1>-W- (wherein W is optionally substituted aryl or the like; A<1> is -NR<1>-, a single bond, -C(O)-, or the like;...  
WO/2002/072536A1
The invention relates to novel compounds having Vanilloid Receptor (VR1) antagonist activity, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders.  
WO2002030876A3
The present invention relates to compounds of the general formula (I), process for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of...  
WO2001007020A3
The invention relates to the use of carboxylic acid amides of general formula (I) for inhibiting telomerase, wherein A, B and R1 to R5 are defined as per claim (1). The invention also relates to novel carboxylic acid amides of general fo...  
WO/2002/072083A1
The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of re...  
WO/2002/070493A1
The invention relates to a bisaryl derivative of the formula I, wherein (R, R) is selected from (H, H), O, (H, CH¿3?), (H, OH) and (H, CN); Ar is substituted phenyl; and A is a group of following formula II, III, IV or V: The compounds ...  
WO/2002/070471A1
Compounds of the formula (I) in which R?1¿ is CN, or C(=NH)-NH¿2?, CON(R?3¿)¿2? or [C(R?4¿)¿2?]¿n?N(R?3¿)¿2?, each of which is unsubstituted or monosubstituted by C(=O)R?3¿, COOR?3¿, or?3¿ or by a conventional amino-protectin...  
WO/2002/070467A1
The invention relates to new diphenylurea having the formula (I) or a salt thereof, where Y is CO=O, C=S, C=NH, (C=O)¿2? or SO¿2?; and to processes for the preparation of these compounds and to their use in the treatment of protozoal d...  
WO/2002/068380A1
The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders.  
WO2002012534A3
The present invention relates to compounds made by a subset of modules from one or more polyketide synthase ("PKS") genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring p...  
WO2000066104A9
ACE-2 inhibiting compounds are disclosed. Methods of using the compounds and pharmaceutical compositions containing the compounds are also claimed.  
WO2002002520A3
The present invention is disubstituted amines of formula (I) and disubstituted amines of formula (II) useful in treating Alzheimer's disease and other similar diseases.  
WO2000067746A9
A method for the inhibition of the binding of alpha 4 beta 1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions com...  
WO2002002506A3
The present invention is substituted amines of formula (XV) useful in treating Alzheimer's disease and other similar diseases.  
WO/2002/064139A1
This invention relates to the use of the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity for the treatment of Parkinson's disease.  
WO/2002/064128A1
The invention relates to the use of a compound that modulates the association of caspase-9 to Apaf-1 for the treatment of diseases characterized by excessive or insufficient cell death.  
WO/2002/064549A1
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certan plasma lipid levels, including high density liporprotein-cholesterol and to lower certain other plasma lipid lev...  
WO/2002/064130A1
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipo-protein-cholesterol and to lower certain plasma lipid levels, ...  
WO/2002/062763A2
This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.  
WO/2002/062762A2
Compounds of formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.  
WO2002002518A3
The present invention is disubstituted amines of formula (I) and disbustituted amines of formula (II) useful in treating Alzheimer's disease and other similar diseases.  
WO2002006189A3
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salt and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associa...  
WO/2002/059077A1
It is intended to provide drugs which have cholesteryl ester transfer protein inhibitory effect and are useful as blood lipid lowering agent, etc. Namely, compounds represented by the following general formula (I), salts thereof, and med...  
WO/2002/059080A2
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invent...  
WO2002002505A3
The present invention is substituted amines of formula (X) useful in treating Alzheimer's disease and other similar diseases.  
WO/2002/059102A2
The invention concerns novel products of formula (I) wherein: Y represents oxygen or sulphur; Z represents C=CH2, CH-CH3 or CH2; R1 represents hydrogen, morpholinyl or the radical (II) wherein the two nitrogen atoms are linear or form a ...  
WO/2002/059081A2
Urea and amide derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful area and amide ...  
WO/2002/057242A2
Novel antagonists of &agr 4β1 integrin and/or &agr 4β7 integrin of the general Formula (I): wherein R1, R2, R5, L1, L2, Rb, W and Z are as defined in any one of claims 1 to 13, A represents -CH- or a nitrogen atom, and p is from 0 to 4.  
WO/2002/057233A1
The present invention related to compounds of the formula (I) or a pharmaceutically acceptable addition salt and/or hydrate thereof, or where applicable, a geometric or optical isomer or racemic mixture thereof; which are useful for the ...  

Matches 901 - 950 out of 6,256