Acyclic or Carbocyclic Compounds

Matches 151 - 200 out of 824	< 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 >

Document	Document Title
WO/1999/005093A1	ISOCYANOALKYL CARBONIC ACID DERIVATIVES, THEIR CONVERSION INTO SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES BY ISOCYANIDE-MULTICOMPONENT REACTIONS, AS WELL AS THESE SECONDARY AMIDOALKYL CARBONIC ACID DERIVATIVES. The invention relates to compounds with general formula (I) in wchich A is a group having formula (a) or (b), and Z is an O or S atom. The invention also relates to their further processing to form new secondary amidoalkyl carbonic acid ...
WO/1999/001427A2	NOVEL NITRIC OXIDE-RELEASING AMIDINE- AND ENAMINE-DERIVED DIAZENIUMDIOLATES, COMPOSITIONS AND USES THEREOF AND METHOD OF MAKING SAME The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitr...
WO/1998/056753A1	PREPARATION AND USES OF N-METHYLNITRONE Oxidation of secondary amines with hydrogen peroxide and sodium tungstate is reported to give good yields of nitrones. However, when using dimethylamine in this manner, a considerable amount of N,N-dimethylformamide was produced as a co-...
WO/1998/051697A2	METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS The invention relates to a method for producing polymers having nucleo-bases as side groups by means of multi-constituent reactions, specially the Ugi reaction. By virtue of the multiconstituent nature of production, the properties of th...
WO/1998/050325A2	BUILDING BLOCKS DERIVED FROM 1,2-AMINOALCOHOLS Disclosed are novel compounds represented by structural Formula (XX), (XXI) or (XXII); R�1?, R�21? and R�22? are independently an aliphatic group, a substituted aliphatic group, an aromatic group or a substituted aromatic group. R�...
WO/1998/027050A1	PROCESS FOR PREPARING A NAPHTALENAMINE DERIVATIVE The present invention relates to a process for preparing cis-(1S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro- 1-naphtalenamine and its acid addition salts wherein N-methyl-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-naphtale ne-1-...
WO/1998/023565A2	AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS Aminoguanidine and alkoxyguanidine compounds, including compounds of formula $i((I)) wherein X is O or NR?9� and R?1�-R?4�, R?6�-R?9�, R?11�, R?12�, R?a�, R?b�, R?c�, Y, Z, n and m are set forth in the specification, ...
WO/1998/019988A1	ALPHA-BRANCHED FLUOROALKYLCARBONYL FLUORIDES AND THEIR DERIVATIVES Briefly, in one aspect, the present invention provides compositions of open-chain, $g(a)-branched fluoroalkylcarbonyl fluorides, and derivatives thereof.
WO/1998/019996A1	NITRIC OXIDE DONOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PULMONARY HYPERTENSION AND OTHER INDICATIONS The invention is directed to nitric oxide (NO) donor compounds (such as those of formulae 1-4) and to pharmaceutical compositions containing such nitric oxide (NO) donor compounds, for delivering NO to the apical surface of a mucosa, whe...
WO/1998/013332A1	NITRONE DERIVATIVES Compounds represented by general formula (I) and pharmaceutically acceptable salts thereof, useful as the remedies for nerve degeneration diseases such as neuropil degeneration diseases, wherein Ar is optionally substituted phenyl or an ...
WO/1998/013358A1	O?2�-ARYLATED OR O?2�-GLYCOSYLATED 1-SUBSTITUTED DIAZEN-1-IUM-1,2-DIOLATES AND O?2�-SUBSTITUTED 1-[(2-CARBOXYLATO)PYRROLIDIN-1-YL]DIAZEN-1-IUM-1,2-DIOLATES Diazeniumdiolates, wherein the N?1� position is substituted by an inorganic or organic moiety and the O?2�-oxygen is bound to a substituted or unsubstituted aromatic group, are provided. Also provided are O?2�-glycosylated 1-substi...
WO/1998/009955A1	PROCESS AND NOVEL INTERMEDIATES This invention provides intermediates and processes useful for the preparation of crytophycin compounds.
WO/1998/008496A1	LIPOPHILIC POLYAMINE ESTERS FOR THE SITE SPECIFIC DELIVERY OF NITRIC OXIDE IN PHARMACEUTICAL USE A pharmaceutical composition of matter for delivering nitric oxide. The composition is an amine that was reacted with nitric oxide. The composition of matter is lipophilic and insoluble and therefore delivers nitric oxide to the specific...
WO/1998/003478A1	NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES The invention relates to nitrone derivatives of formula (I): wherein R?1� represents: -(CH�2? )�m?-(phenyl optionally substituted by one or more groups R?8� which may be the same or different), or pyridyl, furyl or thienyl option...
WO/1998/003479A1	NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES The invention relates to nitrone derivatives of formula (I), wherein: R?1� represents: -(CH�2?)�m?-(phenyl optionally substituted by one or more groups R?8� which may be the same or different); or pyridil, furyl or thienyl option...
WO/1997/049675A1	PER(POLY)FLUORINATED POLYOXYETHYLATED CARBAMATES Per(poly)fluorinated polyoxyethylated carbamates of general formula (I) in which RF represents a perfluorinated group containing between 1 and 18 carbon atoms, W represents an oxo group or nothing, n is an integer from 1 to 10, m is from...
WO/1997/049715A1	GLYCOSIDIC PERFLUOROALIPHATIC SURFACE-ACTIVE AGENTS, THEIR PREPARATION AND USE The present invention is concerned with the synthesis of new carbamates derived from monosaccharides or disaccharides and their precursors. These compounds may be used as surface-active agents or co-surface-active agents of yolk phosphol...
WO/1997/049428A1	REMEDIES FOR MYELOMA TO BE USED TOGETHER WITH NITROGEN MUSTARD ANTITUMOR AGENTS Remedies for myeloma wherein nitrogen mustard antitumor agents and an anti-IL-6 receptor antibody are used together. Namely, remedies for myeloma containing the anti-IL-6 receptor antibody which are to be used together with the nitrogen ...
WO/1997/039751A1	COMPOSITIONS COMPRISING A NITRONE COMPOUND FOR USE IN TREATING OCULAR INFLAMMATION Ophthalmic pharmaceutical compositions containing a pharmaceutically acceptable ophthalmic carrier and an inflammation-treating amount of a nitrone compound are disclosed. Also disclosed are methods for treating ocular inflammation condi...
WO/1997/029070A1	PERFLUORO(ALKOXYCYCLOALKANE)CARBONYL FLUORIDE COMPOSITIONS AND THEIR USE This invention provides perfluoro(alkoxycycloalkane) carbonyl fluoride compounds wherein, pendant from the fluorinated ring, are from 2 to 5 perfluoroalkoxy groups having from 1 to 4, preferably 1 to 2, carbon atoms with the proviso that...
WO/1997/026240A1	CONFORMATIONALLY RESTRICTED AROMATIC INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structure (I) or (IA) or (IB) including pharmaceutically acceptable sa...
WO/1997/019054A1	AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective a...
WO/1997/015280A1	USE OF AT LEAST ONE NO SYNTHASE INHIBITOR FOR TREATING SENSITIVE SKIN The use of at least one NO synthase inhibitor as the active principle in a cosmetic composition for treating and/or preventing sensitive skin is disclosed. The use of at least one NO synthase inhibitor for preparing a pharmaceutical and ...
WO/1997/010226A1	PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND The invention relates to a process for preparing a compound of formula (I) in which A is chlorine or 3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazin-5-yl; to intermediates used in this process; to the use of these intermediates; and to a ...
WO/1997/007094A1	POLYHYDROXY ALKYL AMIDAMINE OXIDES The amine oxides described correspond to formula (1) in which RCO is an aliphatic acyl radical with 6 to 22 carbon atoms, Z is a linear polyhydroxy hydrocarbon radical with at least 3 possibly oxalkylated hydroxyl groups, m is a whole nu...
WO/1997/003946A1	PROCESS FOR PRODUCING ORGANIC NITROGEN COMPOUNDS, SPECIAL ORGANIC NITROGEN COMPOUNDS AND MIXTURES OF SUCH COMPOUNDS AND THEIR USE AS FUEL AND LUBRICANT ADDITIVES The invention relates to the production of organic nitrogen compounds, especially aminoalkanes, alkyloximes, alkylnitrons or mixtures thereof having only one nitrogen-functional grouping and no alcoholic hydroxyl groups in the molecule, ...
WO/1997/003034A2	POLYNITRILE OXIDES The present invention is an aqueous dispersion of a stable polynitrile oxide represented by the structure: R-(CN-O-)x, whre x is an integer greater than 1, R is an aromatic, aliphatic, or cycloaliphatic group having at least one substitu...
WO/1997/003142A1	FORMULATIONS CONTAINING POLY-(NITRILE OXIDE) REAGENTS Curable compositions contain: (a) at least one nitrile oxide monomer which contains on average more than one stable nitrile oxide group per molecule; and (b) at least one polyunsaturated monomer which: (1) has a weight average molecular ...
WO/1996/040665A1	N-SUBSTITUTED PIPERAZINE NONOATES There are disclosed N-substituted piperazine NONOate compounds having structure (I) wherein M is a pharmaceutically acceptable cation, x is the valence of the cation, and R is selected from the group consisting of: an unsubstituted or su...
WO/1996/030336A1	SUBSTITUTED 1,3,9,11-TETRAOXA-4,5,7,8-TETRAAZAUNDECADIENE-4,7-DIOXIDES-5,7, THEIR PREPARATION AND APPLICATION The present invention relates to new chemical compounds - substituted 1,3,9,11-tetraoxa-4,5,7,8-tetraazaundecadiene-4,7-dioxides-5 ,7 with general structure F1, to methods of their preparation, and to pharmaceutical compositions, contain...
WO/1996/015797A1	PHARMACEUTICAL COMPOSITIONS COMPRISING NITRIC OXIDE-RELEASING BIOPOLYMERS A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N2...
WO/1996/006822A1	ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF The present invention relates to compounds of formula (I) wherein: A is an optionally substituted ring system as defined herein; B is an optionally substituted 5- or 6-membered heteroaryl ring system or optionally substituted phenyl; D i...
WO/1995/035283A1	TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS Compounds of general formula (1) are described, formula wherein =W- is (1) =C(Y)- where Y is a halogen atom, or an alkyl or -XRa group where X is -O-, -S(O)m- [where m is zero or an integer of value 1 or 2], or -N(Rb)- [where Rb is a hyd...
WO/1995/032270A1	LOW FOAM BRANCHED ALKYLDIMETHYLAMINE OXIDES An amine oxide having formula (I), wherein the R1 groups are independently selected from C1-C4 alkyl or alkoxy groups and R2 is a branched chain C11-C16 alkyl group; a detersive compositions containing such amine oxide with amphoteric su...
WO/1995/029157A1	PROCESS FOR MAKING SOLID FORMULATIONS CONTAINING AMINE OXIDE SURFACTANTS Disclosed is a process for making solid formulations containing amine oxide surfactants. Maleic acid, or a water soluble salt thereof, is admixed with an aqueous liquid amine oxide formulation, which formulation preferably contains from ...
WO/1995/029156A1	SOLID COMPOSITIONS CONTAINING AMINE OXIDE-MALEIC ACID SALTS Disclosed are solid, concentrated, amine oxide surfactant compositions containing amine oxide-maleic acid salts. The molar ratio of maleic acid to amine oxide in such salts is about a 1:1. The salts are soluble in water at 25� C at a p...
WO/1995/023885A1	PROCESS FOR PURIFYING AQUEOUS SOLUTIONS OF TERTIARY AMINO OXIDES The invention relates to a process for producing cellulose shaped bodies, said process comprising the following steps: (A) dissolving cellulose in an aqueous solution of a tertiary amino oxide to form a cellulose solution which can be sh...
WO/1995/023827A1	PROCESS FOR PRODUCING CELLULOSE SHAPED BODIES The invention relates to a process for producing cellulose shaped bodies, said process comprising the following steps: (A) dissolving cellulose in an aqueous solution of a tertiary amino oxide, in particular N-methylmorpholine-N-oxide (N...
WO/1995/018610A1	COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes du...
WO/1995/011882A1	PROCESS FOR REDUCING THE LEVELS OF NITRITE CONTAMINANTS IN AMINE OXIDE SURFACTANTS Amine oxide surfactants contaminated with nitrite are treated under acidic conditions with materials such as maleic acid and diethylenetriaminepentaacetate (DTPA) to reduce nitrite levels below 1 ppm. Thus, C12-13 dimethyl amine is oxidi...
WO/1995/011227A1	NOVEL SPIN TRAP NITRONYL HINDERED PHENOLS The invention is the use of nitronyl substituted hindered phenols as antioxidants in therapeutic applications. In the preferred embodiment the compositions have general formula (I), wherein R1 is hydrogen, an alkyl or an aryl and R2 is a...
WO/1995/008976A1	ACTIVE SUBSTANCE DELIVERY SYSTEM The present invention relates to compositions comprising a compound containing a nitrogen linked by an ester bond to an active substance radical having an efficient deposition of the active substance radical to a surface followed by dela...
WO/1994/027957A1	COMPOUNDS WHICH RELEASE NITRIC OXIDE Chemical derivatives of nitric oxide are provided which are stable indefinitely in oxygen-containing solutions until photolysis, whereupon they release NO. These compounds have the general formula (I): A-N+(O-)=N-O-B wherein A is typical...
WO/1994/025433A1	CARBAMOYL HYDROXYLAMINE AND USE THEREOF IN POLYMER CHEMISTRY Described is a compound of formula (I) in which A is an n-valent organic group and n is an integer greater than 1.
WO/1994/024361A1	USE OF ALKOXYLATED POLYAMINES AND THEIR N-OXIDES, AS WELL AS THEIR PARTIAL AMIDES WITH CARBOXYLIC ACIDS, AS LEATHER DYEING AUXILIARY AGENTS Alkoxylated polyamines of formula (I) and their partial amides with carboxylic acids, in which all or some aminobasic nitrogen atoms may be N-oxides, are used as leather dyeing auxiliary agents. In formula (I), R1 stands for a C1-C30-alk...
WO/1994/012470A1	AZOXYCYANOBENZENE DERIVATIVES This invention relates to certain azoxycyanobenzene derivatives of general formula (I), in which n is 0, 1, 2 or 3; each R independently represents a halogen atom, nitro, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy group; and each of R...
WO/1994/011334A1	SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES Compounds of general formula (I) in which the index and the constituents have the meanings below: n: 0, 1, 2, 3 or 4; X: CHOCH3, CHCH3 or NOCH3; Y: O or NH; R1: nitro, cyano, halogen, alkyl, alkyl halide, alkoxy, alkoxy halide, alkylthio...
WO/1994/010118A1	TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION Compounds are described in formula (1), wherein Y is a halogen atom or a group -OR1, where R1 is an optionally substituted alkyl group; R2 is an optionally substituted cycloalkyl or cycloalkenyl group; R3 is a monocyclic or bicyclic aryl...
WO/1994/005629A1	AZOXY COMPOUND An azoxy compound represented by general formula (I), which has an excellent fungicidal activity against fungi which infect warm-blooded animals, agrohorticultural crops or fruits, thus being useful as medicine, veterinary drug and agroh...
WO/1994/001430A1	2,5-DIARYL TETRAHYDRO-THIOPHENES, -FURANS AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISORDERS 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chem...

Matches 151 - 200 out of 824	< 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 >