Acyclic or Carbocyclic Compounds

Matches 351 - 400 out of 780	< 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 >

Document	Document Title
JP4660596B2	Fluorsulfonylimides and their production methods
JP4658895B2	A novel derivative of 3,3-diphenylpropylamine The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the inv...
JP4643267B2	A novel propargyl ether derivative for controlling pathogenic microorganisms The invention relates to 4-propargyloxy-benzyl dervatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, optionally substituted alkyl, optionally substituted cycloal...
JP2011032196A	Eg5 INHIBITING COMPOUND To provide an Eg5 inhibiting agent that contains, as an effective component, an uncondensed bicyclic compound comprising a cyclohexyl group, a cyclohexenyl group or a piperidino group as a substituent.The Eg5 inhibiting agent contains, a...
JP2011504505A	Biaryl PDE4 inhibitor for the treatment of pulmonary and cardiovascular disorders The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory di...
JP2011500641A	New sulfamate compounds for pharmaceutical use This invention relates to sulfamates of Formula (I), wherein R1 to R3 and n are defined in the claims, having carbonic anhydrase enzyme inhibitory activity, to medicaments comprising these compounds, to pharmaceutical compositions compri...
JP4598397B2	Cycloalkyl inhibitor of potassium channel function Novel cycloalkyl compounds useful as inhibitors of potassium channel function (especially inhibitors of the K v l subfamily of voltage gated K + channels, especially inhibitors K v 1.5 which has been linked to the ultra-rapidly activatin...
JP4587955B2	A new molecule for developing therapeutic agents for osteoporosis This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention ...
JP4549674B2	2-arylpropionic acid and pharmaceutical compositions containing them (R,S)-2-Aryl-propionic acids are useful as inhibitors of interleukin-8 induced human polymorphonucleated neutrophils (PMN) chemotaxis. (R,S)-2-Aryl-propionic acids of formula (I), their single (R) and (S) enantiomers or salts are useful ...
JP4528768B2	N- (2-phenylethyl) sulfamide derivative as an integrin α4 antagonist Compounds of the following formula and salts thereof are described as integrin alpha4-antagonists, wherein the various symbols are as defined in the specification.
JP4503232B2	Treatment of diseases with malonyl-CoA decarboxylase inhibitor The present invention relates to methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by the administration ...
JP4499357B2	Glucocorticoid receptor regulator Compounds of formula (I) (I), or pharmaceutically acceptable salts thereof are novel glucocorticoid receptor modulators and are useful for treating type II diabetes in a mammal.
JP4495686B2	Sulfamide as a γ-secretase inhibitor Novel sulfamides of formula (I) are disclosed. The compounds exert an inhibitory action on the processing of APP by gamma-secretase, and are therefore useful in the treatment or prevention of Alzheimer's disease.
JP4463991B2	α-Sulfin and α-Sulfone Amino Acid Amides The invention relates to alpha-sulfin- and alpha-sulfonamino acid amides of the general formula Iincluding the optical isomers thereof and mixtures of such isomers, whereinn is a number zero or one;R1 is C1-C12alkyl, C1-C12alkyl substitu...
JP4463990B2	α-Sulfin and α-Sulfone Amino Acid Amides The invention relates to alpha-sulfin- and alpha-sulfonamino acid amides of the general formula Iincluding the optical isomers thereof and mixtures of such isomers,whereinn is a number zero or one;R1 is C1-C12alkyl, C1-C12alkyl substitut...
JP2010083809A	METHOD FOR PRODUCING 3, 3'-DINITROBENZIDINE COMPOUND OR 3, 3'-DIAMINOBENZIDINE COMPOUND To provide a method for producing industrially useful 3, 3'-dinitrobenzidine and 3, 3'-diaminobenzidine, and to provide a dinitrobiphenyl compound of an intermediate for the production of the compounds, and a method for producing the com...
JP2010077150A	METHOD FOR TREATMENT OF DISEASE USING MALONYL-COA DECARBOXYLASE INHIBITOR To provide methods for prophylaxis, management and treatment of specific diseases modulated by inhibition of enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by administration of a composition containing as an act...
JP4405088B2	New Thyroid Receptor Ligand and Method II New thyroid receptor ligands are provided which have general formula (I) in which: n is an integer from 0 to 4; R1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or differe...
JP4395076B2	Tricyclic Steroid Hormone Nuclear Receptor Modulator The present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation comprising administering to a patient in need thereof an effective amount of a compound of the formula...
JP4390563B2	Substituted phenylalkanoic acid derivatives and their uses A compound represented by the formula (I) or a salt thereof wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R<1>(CH2)k- (wherein k represent...
JP4384028B2	Method for producing sulfamic acid halide The present invention relates to a process for preparing sulfamoyl halides of primary or secondary amines, comprising the following steps: i) reacting a primary or secondary amine A1 with at least equimolar amounts of SO3 or an SO3 sourc...
JP2009286721A	-SUBSTITUTED ACRYLATE DERIVATIVE, AND METHOD FOR PRODUCING THE SAME To provide a polymer compound useful for stain-resistant paint, anti-fogging paint, a stain-resistant resin, an anti-fogging resin, a photosensitive planographic plate or the like, and a new -substituted acrylate derivative which is a ra...
JPWO2008007780A1	Pentazienamide derivative Equation (I) (in equation, R1Represents a substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group, and R2Represents a substituted or unsubstituted aryl, a substituted or unsubstituted aromatic hete...
JP4351888B2	A method for producing an aromatic compound derivative by reacting an aromatic compound substituted with a sulfamoyloxy group or a sulfinamoyloxy group with a nucleophile.
JP4347696B2	Industrial application methods for sulfamoylation of alcohols and phenols This invention describes a safe method for the production of sulfamoyl chloride from chlorosulfonyl isocyanate and formic acid in the presence of a amide catalyst, taming the hazardous nature of this reaction by circumventing heat accumu...
JP4346113B2	Arylsulfonamides and their analogs and their use in the treatment of neurodegenerative diseases Aryl sulphonamides (I) and their salts are new: R1-A-D-E-G-L-R2 (I) R1 = 6-10C aryl; quinolyl; isoquinolyl; or a group of formula (a); Q = group of formula (i)-(vii): a = 1 or 2; R3 = H; 2-6C alkenyl; 1-6C alkyl; 1-6C acyl; -(CO)b-NR4R5 ...
JP2009536156A	Use of biarylcarboxamide in the treatment of hedgehog pathway-related disorders The invention provides methods for modulating, e.g., antagonizing, the activity of the Hedgehog signaling pathway. In particular, the invention provides methods for inhibiting aberrant growth states resulting from phenotypes such as Ptc ...
JP2009533315A	Antibacterial agent What is provided herein is an aromatic compound substitution agent that is a tRNA synthetase inhibitor and thus can be used as an antibacterial agent. The compounds described herein are Gram-positive, Gram-negative, anaerobic or fungal m...
JP4322871B2	Method for producing chlorosulfonyl isocyanate A method for producing chlorosulfonyl isocyanate by reaction of sulfur trioxide with cyanogen chloride, wherein chlorosulfonyl isocyanate or a solution including chlorosulfonyl isocyanate is used as a reaction solvent, sulfur trioxide an...
JP4320089B2	Phenyl sulfamate derivative Phenyl sulfamate derivatives represented by the following formula or salts thereof have a powerful inhibitory effect on steroid sulfatase and are hence useful for the prophylaxis or treatment of diseases associated with steroids such as ...
JP4300009B2	Acid amide derivatives, their production methods and pest control agents containing them
JP2009143951A	ACID AMIDE DERIVATIVE, METHOD FOR PRODUCING THE SAME AND PESTICIDE CONTAINING THE SAME To provide a pesticide having an extremely high controlling effect on pests in a low medicinal amount, and hardly exerting bad influence to mammalian animals, fishes and the like.The pesticide contains an acid amide derivative expressed ...
JP2009524614A	Acyclic sulfamide derivative The present invention is related to acyclic sulfamide derivatives, useful for the manufacture of a medicament for satiety induction and ingestion control, corporal fat modulation and lipidic metabolism regulation and for the manufacture ...
JP2009520813A	Carbamate antibiotics The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds around the lead compound (3,4-dichloro-phenyl)-carbamic acid 2-isobutoxycarbonylam...
JP4267920B2	Malonyl-CoA decarboxylase inhibitor useful as a metabolic regulator The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases m...
JP2009519231A	Azetidine derivative as a GLYT1 inhibitor The present invention relates to compounds of formula (I); and pharmaceutically acceptable salts thereof and individual enantiomers and diastereomers thereof, as GIyT1 inhibitors for treating neurological and psychiatric disorders.
JP4251410B2	Sulfamate derivatives of anticonvulsants useful in the treatment of psoriasis Anticonvulsant derivatives useful in treating psoriasis are disclosed. 00000
JP4244139B2	New aminocyclohexane derivative The present invention relates to aminocyclohexanol derivatives useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arterioscle...
JP4226672B2	Fluorinated ionic sulfonylimides and sulfonylmethylides, their production methods and their use as photoinitiators Ionic compound is claimed which contains at least one A<+>X<-> group in which A<+> is cation selected from biaryliodonium, arylsulphonium, arylacylsulphonium, diazonium, and organometallic cations containing transition metal complexed by...
JP2009504614A	Therapeutic compounds for Alzheimer's disease The invention relates to substituted 1,2-ethylenediamines of general formula (I), wherein the radicals R1-R13, A, B, L and i are as defined in the description and the claims. The invention also relates to the use thereof for treating Alz...
JP2009504611A	Β-Secretase Inhibitor for the treatment of Alzheimer's disease The invention relates to the substituted 1,2-ethylenediamines of general formula (I), wherein the groups R1 to R13, A, B, L and i are defined as in the description and the claims. The invention also relates to the use thereof in the trea...
JP2009504790A	Methods for Preparing Sulfonylimides and Their Derivatives There are provided processes for preparing compounds of formula (I): wherein each of the R1 is independently F, Cl, Br, or I; and R2 is H, Li, Na, K, or Cs. The processes are particularly useful for preparing compounds used in the field ...
JP4204069B2	Azabicyclic carbamoyloxymutilin derivative for antibacterial use PCT No. PCT/EP97/04166 Sec. 371 Date Jan. 29, 1999 Sec. 102(e) Date Jan. 29, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/05659 PCT Pub. Date Feb. 12, 1998Compounds of formula (3), and pharmaceutically acceptable salts and derivatives ...
JP2008303216A	NEW BIS-PLATINUM COMPLEX WITH POLYMETHYLENE DERIVATIVE AS LIGAND HAVING ANTITUMOR ACTIVITY To provide a method for producing an intermediate for a bis-platinum (II) complex.The method for producing a polymethylene derivative of chemical formula (III) comprises a step of protecting the nitrogen atom of an -amino acid with a ter...
JP2008545650A	Method for producing sulfamide derivative The present invention is directed to novel process for the preparation of sulfonylimine and sulfamide derivatives.
JP4197207B2	Production method of organic sulfur acid or its salt In the presence of an imide compound of the following formula (1), a sulfur oxide is reacted with an organic substrate to yield a corresponding sulfur acid or its salt. This process can efficiently produce an organic sulfur acid or its s...
JP4181408B2	Acylsulfamides for the treatment of obesity, diabetes and dyslipidemia A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment, control or prevention of obesity, non-insulin ...
JP4167301B2	A novel bis-platinum complex using a polymethylene derivative with antitumor activity as a ligand PCT No. PCT/US97/12552 Sec. 371 Date Oct. 14, 1998 Sec. 102(e) Date Oct. 14, 1998 PCT Filed Jul. 22, 1997 PCT Pub. No. WO98/03518 PCT Pub. Date Jan. 29, 1998Bis-platinum(II) complexes with polymethylene derivatives, the method of making ...
JP4163254B2	Carbamoyloxy derivatives of mutilin and their use as antibacterial agents PCT No. PCT/EP96/05874 Sec. 371 Date Dec. 4, 1998 Sec. 102(e) Date Dec. 4, 1998 PCT Filed Dec. 19, 1996 PCT Pub. No. WO97/25309 PCT Pub. Date Jul. 17, 1997Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and ...
JP4163379B2	Sterilizing N-sulfonylglycine alkynyloxyphenethylamide derivative The invention relates to novel pesticidally active compounds of the general formula Ias well as possible isomers and mixtures of isomers thereof,whereinn is a number zero or one; andR1 is C1-C12alkyl that is unsubstituted or may be subst...

Matches 351 - 400 out of 780	< 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 >