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WO/2011/058915A1 |
Disclosed is a process for producing a high-purity aromatic sulfonyl chloride compound readily, on an industrial scale, and with high efficiency. A reaction product produced by reacting sulfuryl chloride, N,N-dimethylformamide and sulfur...
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WO/2011/054530A1 |
Disclosed are compounds of formula (I) that inhibiting GPBP activity, making them useful as therapeutics in antibody-mediated disorders, drug-resistant cancer, inflammation, protein misfolding and ER stress-mediated disorders, and aberra...
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WO/2011/054703A1 |
The invention relates to a method for handling aqueous solutions of methanesulfonic acid in devices consisting of austenitic steel having a chromium content of between 15 and 22 wt. % and a nickel content of between 9 and 15 wt. %.
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WO/2011/051375A1 |
(R,S) 2-aryl-propionamide derivatives, or their single enantiomers (R) and (S) are disclosed useful in the treatment or prevention of symptoms and disorders such as pain and inflammation associated with the bradykinin B1 pathway.
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WO/2011/048919A1 |
Disclosed are: a radiation-sensitive resin composition which can response to (extreme) far ultraviolet rays such as a KrF excimer laser and an ArF excimer laser, X-rays such as a synchrotron radiation beam, and electron beams effectively...
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WO/2011/049940A2 |
There is disclosed a process for making a mono-lithium salt of 5-sulfoisophthalic acid (LiSIPA) having less than 200 ppm sulfate. The process uses a reaction mixture of acetic acid, water, a lithium cation producing compound, and 5-sulfo...
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WO/2011/037975A2 |
The present invention describes the method of making anionic ether sulfate surfactants by alkoxylation of a GA using PO and/or EO followed by a sulfation reaction. The GA of the present invention is made by a facile and inexpensive metho...
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WO/2011/037613A1 |
The present invention relates to salts of 2-(2-((4-(((4-chlorophenyl)(phenyl)-carbamoyloxy)methyl)cycl
ohexyl)methoxy)acetamido)ethanesulfonic acid (Compound 1) and crystalline forms, solvates and hydrates thereof. The present invention ...
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WO/2011/033194A1 |
The invention relates to a method for synthesizing ivabradine of formula (I) and to the addition salts thereof with a pharmaceutically acceptable acid.
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WO/2011/030921A1 |
Disclosed are a biphenyltetrasulfonic acid compound represented by formula (1), and a polymer which contains a structural unit originating in said biphenyltetrasulfonic acid compound. In formula (1), R1 represents a hydrogen atom, a cati...
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WO/2011/030737A1 |
Disclosed is a radiation-sensitive composition capable of forming a chemically amplified positive resist film, which is effectively sensitive to (extreme) far ultraviolet rays such as KrF excimer lasers, ArF excimer lasers, and EUV, X-ra...
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WO/2011/024988A1 |
Disclosed is a novel ionic liquid which can be produced at low cost, is safe for the environment, and has a low viscosity and a low melting point. Specifically disclosed is an ionic liquid represented by general formula [1] (wherein R1 t...
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WO/2011/025267A2 |
The present invention relates to metformin methanesulfonate, to a method for preparing same, to a pharmaceutical composition comprising same, and to a combined formulation comprising same. The metformin methanesulfonate of the present in...
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WO/2011/025269A2 |
The present invention relates to metformin taurate, to a method for preparing same, to a pharmaceutical composition comprising same, and to a combined formulation comprising same. The metformin taurate of the present invention has superi...
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WO/2011/022429A2 |
The present invention relates to a process for the preparation of alkyl esters of (S) 2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)-N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-diflu...
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WO/2011/017800A1 |
The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in ...
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WO/2010/123599A9 |
This disclosure relates to compositions and methods including for the inhibition, prevention, and/or treatment of microbial infections, including infections from such pathogens as Staphylococcus aureus.
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WO/2011/016523A1 |
Disclosed are: a process for producing a bis-quaternary ammonium salt with high efficiency; and a novel synthetic intermediate for the process. Specifically disclosed are: a process for producing a bis-quaternary ammonium salt represente...
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WO/2011/013615A1 |
Provided is a fluorine-containing compound represented by general formula (1), which exhibits an excellent surface tension lowering effect, though the fluorine-containing compound is a low-environment-load type, fluorine-containing mater...
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WO/2011/013834A1 |
Disclosed is a method for producing a biaryl compound represented by formula (2): Ar-Ar, wherein Ar represents an aromatic group which can have a substituent, comprising carrying out the coupling reaction of a compound represented by for...
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WO/2011/013635A1 |
Disclosed is a protected 2-fluoropropylamine (general formula [1]) having a leaving group at the 3-position or a protected N-alkyl-2-fluoropropylamine (general formula [2]) having a leaving group at the 3-position, which can be highly ef...
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WO/2011/009947A1 |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt, a stereoisomer or a mixture in all proportions of stereoisomers thereof, in particular a mixture of enantiomers, such as a racemic mixture,...
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WO/2011/010524A1 |
Provided is a process by which high-purity alkoxybenzenesulfonyl chlorides can be produced industrially, easily and efficiently. A process for the production of alkoxybenzenesulfonyl chlorides represented by general formula (2) [wherein ...
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WO/2011/009541A1 |
The present invention relates to the preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxy
phenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxy
p...
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WO/2011/006621A1 |
This invention relates to novel cyclo alkyl compounds suitable for labeling by 18F, methods of preparing such a compound, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, ...
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WO/2011/008570A2 |
Provided are new anionic surfactants and methods of their preparation and use. The surfactants are compounds of the formula I: wherein R, R1, R2, R3, R4, R5, and R6 are as defined herein.
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WO/2010/149262A1 |
The present invention relates to novel compounds having fluoridated terminal groups, to the use thereof as surfactant substances, and to a method for producing said compounds.
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WO/2010/150205A1 |
Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which are useful for being biologically and pharmacologically screened, an...
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WO/2010/148177A2 |
Embodiments of the present disclosure provide for chloride channel or transporter compounds or compositions (inhibitors or agents), methods of synthesizing these compounds or compositions, methods of treatment using these compounds or co...
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WO/2010/147228A1 |
A pattern forming method, including: (i) forming a film from a chemical amplification resist composition; (ii) exposing the film, so as to form an exposed film; and (iii) developing the exposed film by using a developer containing an org...
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WO/2009/124371A9 |
The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity. In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by ...
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WO/2010/135350A2 |
Disclosed herein are methods and compounds useful in preparing N-(3,4-dimethyl-5-isoxazolyl)-2-(4-(2-butyl-4-oxo-l,3-diazos
piro[4.4]non-l-en-3yl)methyl-2-ethoxymethylphenyl)phenylsulf
onamide.
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WO/2010/130378A1 |
Compounds of the general formula (I) a process for their preparation and their use for dyeing and/or printing organic substrates.
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WO/2010/130379A1 |
Compounds of the general formula (I) a process for their preparation and their use for dyeing and/or printing organic substrates.
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WO/2010/121719A1 |
This invention relates to novel compounds suitable as precursors for the preparation of certain F-18 labeled positron emission tomography (PET) tracers. Furthermore, the invention relates to the preparation of such precursor molecules an...
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WO/2010/124151A1 |
Embodiments of the present invention disclose an agricultural composition that is a field ready spray or a tank mix that includes at least one nitrogen containing isethionic acid salt, at least one agriculturally active ingredient, and a...
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WO/2010/123060A1 |
Provided is a fatty acid alkyl ester sulfonate metal salt mixture comprising: (a) a fatty acid alkyl ester sulfonate metal salt for which the heat-absorption peak area between 50°C and 130°C is less than 50% of the total absorption pea...
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WO/2010/118889A1 |
Process for manufacturing 1-amino-1,3,3, 5, 5-pentamethylcyclohexane mesylate comprising step (i): (i) reacting 1-amino-1, 3, 3, 5, 5-pentamethylcyclohexane with methane sulfonic acid in a solvent or a mixture of two or more solvents sel...
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WO/2010/116736A1 |
Disclosed is a method for producing an alkanolamine salt of an α-sulfo fatty acid alkyl ester, comprising: a step of sulfonating a fatty acid alkyl ester to obtain a sulfonated compound; a step of reacting an alcohol and hydrogen peroxi...
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WO/2010/114144A1 |
The present invention provides a novel propylene oxide and a method for producing the same as well as a production method using the novel propylene oxide. The present invention is 1,1,3-trichloro-2,3,3-trifluoropropylene oxide. The prese...
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WO/2010/104177A1 |
A fluoroalkanesulfinic acid ammonium salt is obtained using an organic base when a bromofluoroalkyl carboxylate ester is sulfinated using a sulfinating agent. The fluoroalkanesulfinic acid ammonium salt is oxidized, thereby obtaining a f...
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WO/2010/104178A1 |
An ammonium hydroxyfluoroalkanesulfinate is obtained by using an organic base while sulfinating a bromofluoroalcohol with a sulfinating agent. An ammonium hydroxyfluoroalkanesulfonate is obtained by oxidizing said ammonium hydroxyfluoroa...
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WO/2010/101204A1 |
A binaphthyldisulfonic acid compound represented by formula (1a) or (1b). (In the formulae, R1 is a hydrogen atom, an alkyl, or a metal ion (e.g., Li, Na, K, Mg, or Ca); R2 is a halogen atom, a heavy hydrogen atom, a trialkylsilyl, dihyd...
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WO/2010/099532A2 |
A method for the purification of 5-sulfoisophthalic acid wherein via the application of an acetic acid wash while said crude cake of 5-sulfoisophthalic acid is filtered.
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WO/2010/094554A1 |
The invention relates to an improved method for releasing an organic acid, preferably a carbon, sulfone or phosphone acid, particularly an alpha or beta hydroxycarbon acid, from the ammonia salt thereof by releasing and removing ammoniac...
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WO/2010/094630A1 |
The invention relates to a method for converting ammonium salts of organic acids into the respective free organic acids, wherein an aqueous solution of the ammonium salt is brought into contact with an organic extraction agent, and the s...
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WO/2010/093601A1 |
The present invention relates to sulfonic acid containing compounds of formula IB, in which G, R1, R3 and T are as defined in the claims, that bind to thyroid receptors in the liver. Activation of these receptors results in modulation of...
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WO/2010/085278A1 |
Sulfo-estolides and methods of making them are described. Useful methods include acid side bleaching, partial hydrogenation of the fatty acid, pretreatment of the fatty acid to provide color inhibition, acid side hydrolysis of the sulfo-...
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WO/2010/084976A1 |
Disclosed is a method for manufacturing a conjugated aromatic compound, which is characterized in that an aromatic compound (A), wherein one or two leaving groups selected from a group comprised of an iodine atom, bromine atom and chlori...
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WO/2010/076898A1 |
A process for producing a low-fluorine-content perfluoroalkylsulfonic acid salt in a simple manner in high yield. An organic solvent is added to at least one compound selected from perfluoroalkylsulfonic acid salts represented by the ge...
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