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JP2544123B2 |
Compounds represented by general formula (I), (wherein Y-Z represents (II), -CH=CH- or -CH2CH2-, R1 and R2 each represents a substituent, R3 represents hydrogen, alkyl or alkoxy, R4 represents hydrogen, alkyl, optionally substituted alke...
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JP2541582B2 |
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JP2542620B2 |
The method of treating hypertension with neutral metalloendopeptidase (NMEP) inhibitors, NMEP inhibitors in combination with atrial peptides, and NMEP inhibitors in combination with angiotensin converting enzyme inhibitors, as well as ph...
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JP2536516B2 |
NEW MATERIAL:A compound shown by formula I {R<1> is 1-10C aliphatic group (which may contain 0-3 unsaturated bonds and may be replaced with lower alkoxy or lower alkoxycarbonyl) or H; X is H or OH-protecting group; Y is group shown by fo...
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JP2530848B2 |
O-Substituted hydroxylamines (I) H2N-O-CH2-R (I) (R = H, org. radical) and salts thereof are prepared by reacting a cyclic imidoether II of a 1,4- or 1,5-dicarboxylic acid which contains an ether grouping -O-CH2-R with a basic compound, ...
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JP2527757B2 |
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JP2528332B2 |
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JP2526359B2 |
PURPOSE: To quickly and precisely measure nortripterin by producing an antibody by antigenic conjugate, and using an enzyme conjugate as a reagent. CONSTITUTION: A novel compound is formed of a derivative having a functional group conjug...
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JP2525732B2 |
A renin inhibiting compound of the formula: wherein A is a substituent; W is C=O or CHOH; U is CH2 or NR2, provided that when W is CHOH then U is CH2; R1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)m...
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JP2525426B2 |
Fluoroaliphatic ether-containing carbonyl fluoride compounds are prepared by reacting a fluorinated carbonyl compound with hexafluoropropylene oxide in the presence of at least one catalyst selected from potassium iodide, potassium bromi...
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JP2524169B2 |
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JP2525156B2 |
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JP2525199B2 |
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JPH08208595A |
PURPOSE: To obtain a sulfonamide compound having a combination of calcium antagonistic action and monoamine activating action, thus useful as a preventive/therapeutic agent for central nervous diseases such as acute or chronic central ne...
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JPH08208594A |
To obtain the subject sulfone having low toxicity and excellent environmental behavior in addition to economical merits by reacting methyl chloride with an aromatic sulfinic acid. The objective sulfone of formula II, e.g. 4-isopropyl-3- ...
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JP2522911B2 |
The present invention relates to a novel process for the preparation of an alpha , alpha -difluoroalkyl phenyl ether of formula I (I) wherein R1 is hydrogen, halogen, amino, nitro, -SO2-R4, -S-R5, -SO-R6 or -S-S-R7, R2 is hydrogen, halog...
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JP2522984B2 |
Compounds of the formula (I) (I) in which the Rs independently of one another are H, phenyl, naphthyl or C7-C30alkaryl and R1 is H, C1-C8alkyl, C7-C9aralkyl, C5-C12cycloalkyl, phenyl, naphthyl, C7-C30alkaryl or a group of the formula (II...
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JP2520229B2 |
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JP2520154B2 |
A process for producing carotenoids and carotenoid intermediates via reduction of sulfonyl polyenes with a dithionite in the presence of ammonia or an aliphatic amine, including novel intermediates in this process, which carotenoids are ...
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JP2518014B2 |
This invention relates to methods of preparing and purifying alpha -substituted acetic acids, which comprise treating an alpha -aromatic-substituted acetic acid represented by a specific general formula with a weak alkali while shielding...
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JP2516384B2 |
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JP2518592B2 |
PURPOSE: To provide a novel aromatic aminoketone useful as a photopolymerization initiator for ethylenically unsaturated compounds. CONSTITUTION: There is provided a compound of the formula [wherein Ar is fluorine, an N(R7)(R8) substitut...
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JP2514804B2 |
The copolymerisable photoinitiators have the formula I in which R<1> and R<2> each denote H, C1-6-alkyl or phenyl, R<3> denotes H, C1-6-alkyl, C1-6-alkanoyl or the group Z, R<4> denotes H, halogen, C1-12-alkyl, C1-12-alkoxy, C1-12-alkylt...
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JP2515304B2 |
The invention relates to novel compounds of formula (A) wherein R<2> is the group -C(=NR<1><0>)-SR<9> or -C(=X)-NHR<1><0>, and R, R<3>, R<4>, R<9> and R<1><0> are as stated in the specification, the synthesis thereof, the use of said com...
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JP2514827B2 |
There is disclosed a process for the preparation of compounds of formula I or II (I) (II) from phenols by reaction with formaldehyde and mercaptans in the presence of mono-, di- or trimethylamine or mono- or diethylamine. The symbols R1 ...
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JP2515486B2 |
PURPOSE: To provide a novel substd. di-t-butylcyclohexadienone compd. which is useful as a synthetic intermediate for substd. di-t-butyl phenols as an antiallergic agent. CONSTITUTION: This compd. is represented by formula I (wherein R r...
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JPH08176100A |
To obtain a methionine derivative NMEP(neutral metalloendopeptidase) inhibitor enhancing an activity of atrial natriuretic factor and having a function of reducing blood pressure. This is a methionine derivative NMEP inhibitor, e.g. a ca...
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JP2512522B2 |
A sulfur-containing acryl oligomer composition represented by formula (I): wherein R1 represents a hydrogen atom or a methyl group; R2 and R3 each represents an alkylene group having from 1 to 12 carbon atoms; R4 represents an alkylene g...
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JP2509623B2 |
A compound of the formula wherein R is halogen, C1-C2 alkyl, C1-C2 alkoxy, nitro; cyano; C1-C2 haloalkyl, or RSOn- wherein n is 0 or 2 and R is C1-C2 alkyl; R<1> is hydrogen or C1-C4 alkyl; R<2> is hydrogen or C1-C4 alkyl; or R<1> and R<...
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JP2511285B2 |
This invention relates to an improvement in a process for making 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol) which comprises reduction of bis(3,5-di-tertiarybutyl-4-hydroxyphenol)po...
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JP2510839B2 |
PURPOSE: To prepare the new compound derivatives, useful as bioreversible prodrug moieties, by allowing specific amines and acyloxyalkylcarbonate compounds to react with each other in the presence of aprotic polar solvent and a catalyst....
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JP2510089B2 |
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JP2511281B2 |
In a process for making 2,6-di-tertiarybutyl-4-mercaptophenol by the Zn/acid reduction of bis (3,5-di-tertiarybutyl-4-hydroxyphenyl)polysulfide the addition of catalytic amounts of lead to the zinc reagent results in substantial improvem...
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JP2509288B2 |
A radiation-polymerisable mixture contains a polymeric binder, a radiation-initiated polymerisation initiator and a polymerisable compound of the formula I in which R is alkyl, hydroxyalkyl or aryl, R<1> and R<2> are each H, alkyl or alk...
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JP2509583B2 |
This invention is concerned with insecticidal compositions containing N'-substituted-N,N'-diacylhydrazines, methods of using such compositions and with certain of the insecticidal N'-substituted-N,N'-diacylhydrazines which are novel comp...
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JP2509204B2 |
There are provided new alkane and alkoxyalkane derivatives of the general formula I processes for their preparation and insecticidal and acaricidal compositions containing these compounds.R₁ is aryl or aryl substituted by C1-4 alk...
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JP2506093B2 |
The present invention relates to unsubstituted diacylhydrazine compounds and novel substituted diacylhydrazine compounds useful as insecticidal agents. These diacylhydrazines control insect populations and protect agronomic crops, trees,...
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JP2506757B2 |
A process for the preparation of alkylthioalkanoate salts by reaction of an alkali metal alkylmercaptide with a lactone in the presence of an aprotic polar organic solvent. Preferably, the alkali metal mercaptide is prepared by reaction ...
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JP2507510B2 |
Colored dihydroxydiphenylsulfone obtained by a reaction between phenol and sulfuric acid is treated with activated carbon and a hydrotalcite compound in a mixed solvent comprising methanol and water at a weight ratio of from 10/90 to 60/...
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JP2506131B2 |
The invention relates to selective herbicidal 4-cyano-4-(fluorophenyl)-3-(substituted-phenyl)butyric acids, esters and derivatives thereof, and a method of selectively controlling undesirable vegetation in rice therewith.
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JP2506766B2 |
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JP2505962B2 |
PURPOSE: To obtain the new compound useful as an intermediate of agricultural pesticides, herbicides, insecticides or the like. CONSTITUTION: A vinyl carbamate of formula I [R1' and R2' are each H, saturated or unsaturated of ethylene se...
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JP2507416B2 |
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JP2503040B2 |
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JP2504113B2 |
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JPH08143490A |
PURPOSE: To obtain the subject new compound useful for labeling an antibody, and the subject new labeled protein labeled by the compound and useful as a diagnostic agent and therapeutic agent for clinical diagnosis and treatment. CONSTIT...
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JP2502311B2 |
A compound of the formula wherein R is halogen, C1-C2 alkyl, C1-C2 alkoxy, nitro; cyano; C1-C2 haloalkyl, or RSOn- wherein n is 0 or 2 and R is C1-C2 alkyl; R<1> is hydrogen or C1-C4 alkyl; R<2> is hydrogen or C1-C4 alkyl; or R<1> and R<...
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JP2502343B2 |
Novel substituted benzamides of the formula XXI wherein R1, R2, R3, R4, R5 and A are as defined herein are useful in the treatment of emesis, and particularly chemotherapy-induced emesis in cancer patients. Some of the compounds are also...
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JP2501852B2 |
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JP2501034B2 |
A method of preparing a compound of the formula wherein R is alkyl, R1 is alkyl or aryl and X is halogen or nitro comprising reacting a compound of the formula wherein R and X are as defined above with a mercaptan having the formula R-SH...
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