| Document |
Document Title |
|
WO/2009/132832A2 |
The invention relates to a method for producing 1,4-benzothiepin-1,1-dioxide derivatives substituted with benzyl groups.
|
|
WO/2009/116487A1 |
Disclosed is a method for producing a sulfone compound represented by formula (1), which comprises a step of obtaining a compound represented by formula (4) by reacting a compound represented by formula (3) with a chlorate or a bromate, ...
|
|
WO/2008/009815A9 |
The invention relates to aromatic sulfonates, the preparation thereof, and the use of the same as the salt of an electrolyte. The sulfonates have the formula [Ar-Z- (CF2)nCFRf-SO3 -] p Mp+ (I), wherein Z is a sulfide, sulfinyl or sulfony...
|
|
WO/2009/096545A1 |
A diurethane compound R2(SO2)m(CH2)nOCONH-R1-NHCOO(CH2)n(SO2)mR2 is produced by a method in which a diamine compound H2NR1NH2 is reacted with a chloroformate compound ClCOO(CH2)n(SO2)mR2 or by a method in which a diisocyanate compound OC...
|
|
WO/2009/090663A1 |
The present invention relates to a novel crystalline polymorph of armodafinil. In another aspect the invention relates to an improved process for preparation of the novel polymorph of armodafinil.
|
|
WO/2009/087666A2 |
The invention relates to an improved process for production of Bicalutamide useful in the treatment of prostate cancer by oxidizing N[4-Cyano-3-trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]
-2-hydroxy-2-methyl propanamide with Hydroge...
|
|
WO/2009/073592A2 |
The present invention provides fluoroalkyl amines represented by the formula R1-Q-S(O)x-C(H),(CH3)r(CH2)z+(1-1)-NHR and fluoroalkyl isocyanates and isothiocyanates represented by the formula RrQ-S(O)x-C(H)l(CH3)r(CH2)Z+(1-1)-N=C=X1, wher...
|
|
WO/2009/038463A1 |
The invention relates to new, highly efficient UV - absorbing compounds, a process for their manufacturing and to uses of these UV - absorbing compounds. The UV - absorbing compounds are in particular UV - A - absorbing compounds accordi...
|
|
WO/2009/025791A2 |
The invention encompasses processes for obtaining pure armodafinil substantially free of disulfide impurities that is suitable for use on an industrial scale. In particular, a processes for purifying armodafinil from bis(diphenylmethyl)d...
|
|
WO/2009/024863A2 |
Disclosed herein is a convenient, commercially viable and environmentally friendly process for the preparation of Armodafinil. The present invention also provides an improved, commercially viable and industrially advantageous process for...
|
|
WO/2009/014431A1 |
The invention pertains to a process for producing a sulphoxide compound, comprising oxidizing a thioether compound with an ozonide formed from a olefin and ozone, to obtain the corresponding sulphoxide compound, provided that the olefin ...
|
|
WO/2008/157216A1 |
The present invention provides a process for the manufacture of an arylmethyl-sulfonylarene, R1CH2SO2R2, wherein R1 and R2 are each independently an optionally substituted phenyl or naphthyl group which process comprises reacting an aryl...
|
|
WO/2008/152462A1 |
The present invention relates to a new process for the preparation of sulfoxides, preferably stereoselective preparation of substituted or unsubstituted chiral sulfinyl derivatives 2-(2- pyridylmethyl) sulfinyl-l H-benzimidazole by oxida...
|
|
WO/2008/149141A2 |
The present invention relates to a process for the preparation of polymorphic forms of the R- and S-enantiomers of modafinil, R-(-)-2-benzhydrylsulfinylacetamide and S-(+)-2- benzhydrylsulfinylacetamide respectively.
|
|
WO/2008/119176A1 |
This invention describes an amidation process whereby amino acids of the Formulae IIA or IIB can be activated and treated with an amine in the presence of a base to yield amides of the Formula (I), without loss of optical purity.
|
|
WO/2008/111563A1 |
[PROBLEMS] To produce an optically active sulfoxide compound which is useful as an intermediate or a starting material for the synthesis of a physiologically active substance such as a pharmaceutical agent, at high optical purity. [MEANS...
|
|
WO/2008/107611A2 |
The invention concerns the use of at least one diol and/or at least one triol as an additive to dimethylsulfoxide (DMSO) in order to lower the crystallization point of same. The DMSO formulation is used in combination with the aforementi...
|
|
WO/2008/093711A1 |
Disclosed is a solid-phase oxidation reaction system for an organic compound, which has such advantages that the system does not require any organic solvent which may adversely affect the global environment, has a high product yield, ena...
|
|
WO/2008/081191A1 |
A process for the preparation of carboprost methyl ester (figure (10)).
|
|
WO/2008/078811A1 |
It is intended to provide a novel herbicide which has a wide range of applications to arable and non-arable lands and the like, and various methods for application to soil treatment, stem and leaf treatment and the like, and exhibits an ...
|
|
WO/2008/075672A1 |
Disclosed is a method for producing a tris(perfluoroalkanesulfonyl)methide acid salt represented by the formula [1], which comprises a step (a) for obtaining a reaction mixture by reacting a methyl magnesium halide represented by the for...
|
|
WO/2008/070143A1 |
The present invention encompasses processes (1) for preparing racemic 2-(benzhydrylsulfinyl)acetic acid by combining the (S)- or the (R)-enantiomer with at least one organic solvent and at least one acid promoter, such as perchloric acid...
|
|
WO/2008/032453A1 |
Disclosed is a commercially advantageous method for producing a hydrazone represented by the formula (4) below. Specifically disclosed is a method for producing a hydrazone according to the following reaction formula.
|
|
WO/2007/150017A2 |
Sulfonamide compounds have been used as biocides for over one hundred years. Sulfonamide compounds are also useful as stain removal agents. This invention is concerned with a process whereby stains on a variety of substrates may be remov...
|
|
WO/2007/117027A1 |
A process for the production of organic oxides, characterized by oxidizing a substrate with a hypohalous acid, a hypohalite, chlorine, bromine, or iodine in the presence of both a catalytic amount of a compound represented by the general...
|
|
WO/2007/115968A2 |
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclope
ntyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secr...
|
|
WO/2007/103221A2 |
The invention encompasses processes for preparing intermediates, such as (R)-modafinic acid and its C1-2 alkyl ester, and the conversion of the intermediates into armodafinil. In particular, the invention concerns: (i) a process for the ...
|
|
WO/2007/100074A1 |
Disclosed are a novel 1-fluoro-1,1-bis(arylsulfonyl)methane useful for monofluoromethylation, and a production method thereof. Specifically disclosed is a method for producing a fluorobis(arylsulfonyl)methane represented by the formula (...
|
|
WO/2007/096034A1 |
A process for preparing 3,4-disubstituted phenylacetic acids of the formula (I) in which X is fluorine, chlorine, bromine or iodine and R is C1-C4-alkylthio, C1-C4-alkylsulfonyl or C1-C4-alkylsulfoxide, starting from a 2-halo-C1-C4-alkyl...
|
|
WO/2007/093772A1 |
The present invention relates to a method of making monomers of the formula X=C (H) -Y-S02-CH2-CH (R) -OH which comprises reacting a compound of the formula Q-Y-S02-CH2-CH (R) -OH with a vinyl-containing organometallic reagent comprising...
|
|
WO/2007/093211A1 |
The invention relates to a process for the treatment of an aqueous mixture comprising a dipolar aprotic compound, comprising: a) an adsorption step, in which the aqueous mixture is brought into contact with a porous adsorbent, whereby th...
|
|
WO/2007/083242A1 |
The invention relates to a process for selectively controlling the crystallisation mesotrione [2-(4-methylsulphonyl-2-nitrobenzoyl)cyclohexane-1 ,3-dione] from aqueous solution in which the aqueous mesotrione solution is introduced to a ...
|
|
WO/2007/070238A2 |
The present invention generally relates to an improved process for preparing modafinil and analogs thereof. The process minimizes impurities and improves the overall yield by oxidizing a modafinil intermediate compound in a reaction mixt...
|
|
WO/2007/054668A1 |
The present invention relates to a process for the synthesis of l-substituted-2-fluoro-4- methylsulfonylphenyl compounds.
|
|
WO/2007/054147A1 |
The present invention relates to the synthesis of antibacterial compounds such as Chloramphenicol and its analogues Thiamphenicol and Florfenicol and particularly to a new reaction for the preparation of the intermediate compound aminodi...
|
|
WO/2007/039127A1 |
The invention relates to a process for the preparation of bicalutamide (I) which comprises oxidizing N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thi
o]-2-hydroxy-2-methyl-propanamide (II) in a solution of peracetic acid in a...
|
|
WO/2007/030385A2 |
An improved method of preparing oxazolidine protected aminodiol compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.
|
|
WO/2007/030386A2 |
An improved method of preparing oxazolidine protected aminodiol compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.
|
|
WO/2007/030405A2 |
A process for preparing ester oxazolidine compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.
|
|
WO/2007/020381A2 |
A process for the preparation of a compound of formula (I) wherein: R is an alkynyl group; R1 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl, phenyl and phenylalkyl, it being possible in turn for all of the receding groups to c...
|
|
WO/2007/013094A2 |
The present invention provides a process for the preparation of an antiandrogen compound, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sul
fonyl]-2-hydroxy-2-methylpropanamide, a compound of formula 1, comprising reacting N-[...
|
|
WO/2007/012183A1 |
A process which includes the reacting of sodium perborate with N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thi
o]-2-hydroxy- 2-methylpropanamide to form bicalutamide. Said process may comprise the reaction of N-[4-cyano-3-(t...
|
|
WO/2006/136135A2 |
The invention relates to a method for decarboxylating C-C cross-linking by reacting carboxylic salts with carbon electrophiles in the presence of transition metal compounds as catalysts. The method represents a decarboxylating cross-coup...
|
|
WO/2006/118322A1 |
The present invention provides an industrially advantageous process for producing hydrazone derivative represented by the formula (5), which is shown by the following reaction formula.
|
|
WO/2006/103689A1 |
The present invention discloses a process for the synthesis of N-[4-Cyano-3-(trifluoromethyl) phenyl]-3-[(4-fluorophenyl) sulphonyl]-2-hydroxy-2-methyl propanamide (Form I). The invention discloses a reagent for oxidation of N-[4-Cyano-3...
|
|
WO/2006/097814A1 |
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of: a) contacting a pro-chiral sulphide of formula (II) with...
|
|
WO/2006/037894A1 |
The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consists in performing an enantioselective oxidation of a sulphur of general formula (I) A - CH2 - S B, wherein: A is a dive...
|
|
WO/2006/034004A2 |
The present invention is directed to a process for preparing certain cysteine protease inhibitors.
|
|
WO/2006/024402A1 |
The invention relates to novel salts of chiral 3-halophthalic acid derivatives of formula (I) from 3-halophthalic acid anhydrides of formula (II), amines of formula (III), a method for the production thereof, the use thereof for producin...
|
|
WO/2006/021743A1 |
A process for selectively controlling the crystallisation of thermodynamically stable Form (1) or kinetically stable Form (2) polymorphs of mesotrione from an aqueous mesotrione solution, said method comprising adjusting the pH of the me...
|
