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Matches 1 - 50 out of 3,894

Document Document Title
WO/2021/071372A1
The invention relates to an improved process of vitamin K2 derivatives preparation via the alkylation of the menadione-cyclopentadiene adduct.  
WO/2021/060517A1
The present invention provides a novel method for producing a derivative of an organic substance that contains one or more groups selected from the group consisting of a sulfanyl group, a selanyl group and a sulfino group. A method for p...  
WO/2021/037683A1
The invention relates to a process for purifying 4,4'-dichlorodiphenyl sulfone comprising: (a) providing a suspension comprising particulate 4,4'-dichlorodiphenyl sulfone in carboxylic acid, (b) carrying out a solid-liquid separation of ...  
WO/2021/037677A1
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone comprising reacting a solution comprising 4,4'-dichlorodiphenyl sulfoxide and at least one linear C6-C10 carboxylic acid as solvent with an oxidizing agent to...  
WO/2021/037672A1
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone, comprising: (a) reacting 4,4'-dichlorodiphenyl sulfoxide and an oxidizing agent in at least one carboxylic acid as solvent to obtain a reaction mixture compr...  
WO/2021/037675A1
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone, comprising: (I) reacting thionyl chloride, chlorobenzene and aluminum chloride forming an intermediate reaction product and hydrogen chloride; (II) mixing aq...  
WO/2021/037682A1
The invention relates to a process for purifying crude 4,4'-dichlorodiphenyl sulfone comprising: (a) dissolving the crude 4,4'-dichlorodiphenyl sulfone which may contain water in an organic solvent in which 4,4'-dichlorodiphenyl sulfone ...  
WO/2021/037680A1
The invention relates to a process for obtaining 4,4'-dichlorodiphenyl sulfone from an organic mixture comprising 4,4'-dichlorodiphenyl sulfone and a linear C6 to C10 carboxylic acid as organic solvent, comprising: (a) cooling the organi...  
WO/2021/036256A1
The present application is suitable for use in the technical field of drug synthesis, and provides a method for synthesizing an HIV protease inhibitor intermediate compounds. The method comprises subjecting compound 1a to an asymmetric t...  
WO/2021/012014A1
The present invention relates to methods for preparing a variety of difluorohaloallylamine derivatives. The present invention also relates to novel difluorohaloallylamine derivatives that are capable of inhibiting certain amine oxidase e...  
WO/2021/007840A1
Provided is a carbamate-substituted styryl sulfone compound, a preparation method, and an application thereof. The carbamate-substituted styryl sulfone compound has a structure represented by general formula I. The carbamate-substituted ...  
WO/2020/257573A1
The invention provides crystalline salt and cocrystal forms of bempedoic acid. Also provided are compositions and pharmaceutical materials including a crystalline salt or cocrystal form of bempedoic acid as well as methods of treating va...  
WO/2020/257571A1
The invention provides methods of preparing 8-hy droxy-2,2, 14,14- tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hy droxy-2,2, 14, 14-tetramethylpentadecanedioic acid. ...  
WO/2020/251012A1
Provided is are an agricultural and horticultural agent, in particular a compound which is useful as the active ingredient of an agricultural and horticultural pest control agent, a mite control agent, a nematode control agent or a disea...  
WO/2020/238779A1
The present invention relates to a method for synthesizing florfenicol. The method comprises the steps of: using sulfuryl fluoride as a fluorinating reagent to fluorinate compound I to obtain a product, and then performing a ring opening...  
WO/2020/207929A1
The invention relates to a process for working up a composition comprising solid 4,4'- dichlorodiphenyl sulfoxide and a solvent, wherein the amount of solvent in the composition is in the range between 5 and 25 wt% based on the total mas...  
WO/2020/186632A1
The present application relates to a benzidine compound and an application thereof, the benzidine compound having the structure as shown in formula I below. Further provided in the present application are a pharmaceutically acceptable sa...  
WO/2020/187795A1
The invention relates to an anionic surfactant of general formula (I) or general formula (II) or mixtures thereof, in which R represents hydrogen or a linear or branched alkyl, alkenyl, alkyl-aryl or alkenyl-aryl group with 5 to 25 C ato...  
WO/2020/161225A1
The invention relates to a process for purifying 4,4'-dichlorodiphenyl sulfoxide comprising: (a) providing a suspension comprising particulate 4,4'-dichlorodiphenyl sulfoxide in monochlorobenzene, (b) solid-liquid separation of the suspe...  
WO/2020/161228A1
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfoxide comprising: (I) reacting thionyl chloride, chlorobenzene and aluminum chloride in a molar ratio of thionyl chloride : chlorobenzene : aluminum chloride of 1...  
WO/2020/161232A1
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfoxide comprising: (a) reacting thionyl chloride, chlorobenzene and aluminum chloride in a molar ratio of thionyl chloride : chlorobenzene : aluminum chloride of 1...  
WO/2020/161100A1
The invention relates to a crystal (C) consisting of at least 95 % by weight of 4,4'-dichlorodiphenylsulfoxide, 0 to 2 % by weight of impurities and 0 to 3 % by weight of an organic solvent (os). Moreover, the present invention relates t...  
WO/2020/161226A1
The invention relates to a process for obtaining 4,4'-dichlorodiphenyl sulfoxide from a liquid mixture comprising 4,4'-dichlorodiphenyl sulfoxide and a solvent, comprising: (a) cooling the liquid mixture to a temperature below the satura...  
WO/2020/135000A1
Disclosed is a preparation method for 3-phenyl-L-serine or derivatives thereof, comprising the following steps: a. obtaining 3-phenyl-L-serine or derivatives thereof on the basis of the reaction formula represented by Formula I, wherein ...  
WO/2020/099285A1
The invention is directed to a catalyst, to a method for manufacturing a catalyst, to a method for manufacturing a bisphenol compound, and to the use of a catalyst. The catalyst of the invention comprises particles having a core and a sh...  
WO/2020/094917A1
The present invention relates to a process for the preparation of arylsulfonylpro- penenitriles. The reaction starting from arylsulfonyl halides is catalyzed by a cat- alyst compound comprising a transition metal. The process is scalable...  
WO/2020/084094A1
The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromati...  
WO/2020/006778A1
The invention belongs to the field of chemical synthesis and discloses a new crystal form of tembotrione, which is a herbicide, a preparation method thereof, and an application thereof as a preparation for plant protection. The present i...  
WO/2019/243179A1
The present invention relates to disubstituted 5(3)-pyrazole carboxylates of the formula (la) or (lb) and a process for their preparation wherein R1, R2, R3, R4 and n are defined as above.  
WO/2019/243178A1
The present invention relates to disubstituted 3-pyrazole carboxylates of the formula (I) and a process for their preparation (I) wherein R1, R2, R3, R4 and n are defined as above.  
WO/2019/237005A1
The present disclosure provides methods for preparing polyunsaturated hydrocarbons, such as E,E-farnesol, farnesyl acetate and squalene, by base catalyzed addition of a dialkylamine to a 3-methylene-1-alkene, such as farnesene. The prese...  
WO/2019/194690A1
Provided is an improved process of vitamin K2 derivatives preparation, represented by formula (I) wherein n is an integer from 3 to 13.  
WO/2019/192058A1
A biochip substrate, a preparation method therefor, and an application thereof. The surface of the biochip substrate contains an active vinyl sulfone group. The preparation method involves a one-step reaction of a compound containing vin...  
WO/2019/180627A1
The present invention relates to an improved asymmetric synthesis of alpha- (diarylmethyl) alkyl amines (hereafter referred to as the compound (1)) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual...  
WO/2019/175149A1
The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.  
WO/2019/088800A3
The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol de...  
WO/2019/088800A9
The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol de...  
WO/2019/091179A1
Disclosed is a method for preparing florfenicol intermediate V, which belongs to the technical field of the preparation of veterinary medicines. The method comprises an addition reaction, a ring-closing reaction, a hydrolysis reaction an...  
WO/2019/088800A2
The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol de...  
WO/2019/062561A1
Provided herein the synthesis methods of firocoxib and an intermediate thereof. The synthesis of the first intermediate is performed through methylation of p-bromopropiophenone or through Friedel-Crafts acylation of bromobenzene, avoidin...  
WO/2019/043289A1
The present invention relates to a process for the preparation of arylsulfonylpro- penenitriles. The reaction starting from arylsulfonyl iodides is catalyzed by light. The process is scalable, environmentally benign and provides the prod...  
WO/2019/039705A1
The present invention relates to a method for separating 5-hydroxymethyl-2-furfural (HMF) and dimethyl sulfoxide (DMSO), the method comprising the steps of: (a) preparing a mixture solution comprising HMF and DMSO; and (b) mixing an orga...  
WO/2019/035479A1
A cyclopropanation method includes reacting an alcohol, an ester, or an aldehyde with a sulfone in an organic solvent containing a base providing a counter cation to form a cyclopropane; and isolating the cyclopropane. When using the a...  
WO/2019/030184A1
The invention relates to new compounds of formula (I) wherein X represents a halogen atom selected from the group consisting of fluorine, chlorine, bromine and iodine, which are useful for the preparation of 4,4'dihalodiphenylsulfones of...  
WO/2019/026479A1
In one or more embodiments, the present invention pertains to a method for purifying dimethyl sulfoxide, the method including a step for adding an alkaline earth metal hydroxide to a material to be distilled that contains dimethyl sulfox...  
WO/2019/026868A1
A method for recovering dimethyl sulfoxide, which comprises a step wherein water and a recovered resist remover that contains dimethyl sulfoxide and at least one compound selected from the group consisting of glycol ethers, glycols and t...  
WO/2018/228079A1
The present invention discloses a fluorescent probe for detecting a sulfenated protein, having the following structural general formula (I). The fluorescent probe has good stability and can be preserved for long-term use. The fluorescent...  
WO/2018/210633A1
The present invention relates to a method for the production of phenylguanidines or the salts thereof by reacting an aniline that has electronegative substituents with a cyanamide-containing mixture.  
WO/2018/189969A1
The present invention is a method for distilling a liquid containing dimethylsulfoxide using a distillation apparatus, wherein: (1) assuming the total of the liquid containing dimethylsulfoxide at the bottom of the distillation apparatus...  
WO/2018/114914A1
The present invention relates to a method for producing (functionalized) biaryls by employing a visible-light-driven, gold-catalyzed C-C cross-coupling reaction system involving boron- and silicon-containing aryl compounds and aryldiazon...  

Matches 1 - 50 out of 3,894