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Matches 651 - 700 out of 5,486

Document Document Title
WO/2005/037777A1
A process for producing bicalutamide, which is represented by the formula (4), (4) which comprises: a step (A) in which the compound represented by the formula (1) is reacted with a peroxycarboxylic acid to obtain the compound (2) repres...  
WO/2005/030710A1
The invention relates to a low-odour tert-dodecanethiol which is particularly suitable as a molecular weight regulator and which can be obtained by acidic catalytic addition of hydrogen sulphide to a hydrocarbon mixture, comprising 10 - ...  
WO/2005/028430A1
The present invention is concerned with an improved process for the preparation of the selective serotonin reuptake inhibitor 3-[(Dimethylamino)methyl]-4-[4-(methylsulfanyl)phenoxy]benze nesulfonamide (L) or (D) tartrate (I) and with int...  
WO/2005/026110A1
A useful novel intermediate and a novel synthesis method which enable an optically active (R)- or (S)-2-amino-3-mercapto-2-methylpropionic acid derivative or a salt thereof which each is useful as an intermediate for medicines, etc. to b...  
WO/2005/021491A1
The invention relates to an oxidic catalyst, which contains cesium and tungsten, for synthesizing alkanethiols from alkanols and hydrogen sulfide, and to a method for producing this catalyst, whereby the molar ratio of cesium to tungsten...  
WO/2005/021493A2
The invention relates to a method of isolating a thiol R'SH from a thiol containing mixture. The method includes the steps of forming a mixed disulphide R'SSR of the thiol R'SH, purifying the mixed disulphide R'SSR and reducing the purif...  
WO/2005/014531A1
A process for the production of N-methacryloyl-4-cyano -3-trifluoromethylaniline which comprises reacting 4-cyano-3-trifluoromethylaniline with methacrylic acid or a reactive derivative thereof in the presence of a polymerization inhibit...  
WO/2005/009928A2
The present disclosure provides methods of synthesizing alkylating agents and methods of use.  
WO/2005/007865A1
Optically active &agr -methylcysteine derivative is efficiently produced from an inexpensive raw material. An optically active 2-amino-2-methyl-1,3-propanediol derivative monoester is produced by esterifying one of the hydroxyls of 2-ami...  
WO/2005/000242A2
Process for making a pharmaceutical composition, comprising: a compound of formula (1) in crystalline form together with a pharmaceutically acceptable carrier or excipient, wherein the compound of formula (1) is present in polymorphic cr...  
WO/2005/000799A1
A process is described for preparing polymorphic form (I) of modafinil with high yields and with low impurity content. The process comprises the steps of (a) reacting (diphenylmethyl)thioacetic acid with a C1-C5 alcohol,(b) oxidation of ...  
WO/2004/113258A1
A process for the production of compounds represented by the general formula (I), salts of the same, or solvate thereof from compounds represented by the general formulae (II) and (III), salts of the same, or solvates thereof, comprising...  
WO/2004/113285A1
The present invention provides a process for the preparation of substantially racemic 2-&lcub [2-(4-hydroxyphenyl)ethyl]thio&rcub -3-[4-(2-&lcub 4-[(methylsulfonyl)oxy]phenoxy&rcub ethyl)phenyl]-propanoic acid which comprises reacting 2-...  
WO/2004/103956A1
The invention relates to a method for the production of dithiodiglycol, wherein mercaptoethanol is reacted with oxygen in the presence of ammonia and/or amines using manganese salts or copper salts containing oxygen or gas mixtures conta...  
WO/2004/101504A1
The invention relates to a stereoselective method of preparing $g(g)-amino vinyl sulphones. The inventive method comprises: the reaction of the corresponding N-protected (1-aminoalkyl) epoxide with a thiol, or an alkaline metal salt ther...  
WO/2004/099129A2
Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are disclosed (Formula I).  
WO/2004/096760A1
The invention relates to a catalyst for synthesizing methyl mercaptan from hydrogen sulfide and methanol, and a method for producing said methyl mercaptans. The inventive catalyst comprises active aluminum oxide on which alkaline tungsta...  
WO/2004/092119A2
The invention relates to an improved method for the production, purification and crystallisation of $g(a)-methylated cysteine or serine derivatives by an acid hydrolysis of corresponding thiazolidine or oxazolidine esters, with the conti...  
WO/2004/090152A1
A process for producing a 2-alkylcysteinamide represented by the general formula (1) or a salt thereof, which comprises hydrolyzing a 4-alkylthiazolidine-4-carboxamide represented by the general formula (2) or a salt thereof. (In the gen...  
WO/2004/089863A1
The invention relates to a process for the production of 2-hydroxy-4-methylthiobutyric acid ammonium salt from 2-hydroxy-4-methylthiobutyronitrile, and to the use of the 2-hydroxy-4-methylthiobutyric acid ammonium salt produced by this p...  
WO/2004/081073A2
Methods of selectively removing counterions from compounds are disclosed. Compounds derived from the methods, such as the compound S-[2-[(1­Iminoethyl)amino]ethyl] -2-methyl-L-cysteine zwitterion with between zero and up to 2 molar equi...  
WO/2004/080956A1
A novel mixed salt of S-[2-[(1-Iminoethyl)amino]ethyl] -2-methyl-L-cysteine is disclosed. The novel mixed salt, S-[2-[(1 Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, may be produced to form crystals that may be arra...  
WO/2004/078705A1
The invention relates to a method for producing &agr -(3-arylthio)-acetophenones of general formula (I), in which substituents R1 and R2, independent of one another, represent C1-C6 alkyl or an optionally substituted phenyl radical or be...  
WO/2004/076404A1
Optically active compounds having thio groups at the 2-position which are important to the production of drugs and so on can be produced with minimized racemization in high yield and at a low cost by chlorinating an optically active comp...  
WO/2004/075827A2
Process for the preparation of 2-[(diphenylmethyl)thioacetamide, an intermediate for the preparation of Modafinil which is a CNS stimulant and used for the treatment of narcolepsia. The process comprises reacting 2-[(diphenylmethyl)thio]...  
WO/2004/075841A2
The present invention is directed to an improved process for preparing modafinil wherein benzhydrylthioacetamide is prepared in high yield and purity by the reaction of a haloacetamide with the reaction product of thiourea and benzhydrol...  
WO/2004/062622A2
A probucol or a probucol derivative can be efficiently converted to a monoester or monoether of probucol by reacting the free hydroxyl-containing probucol or a derivative thereof (by which is meant a probucol compound with at least one s...  
WO/2004/063129A2
A novel, convenient and efficient method for trifluoromethylation of substrate compounds is disclosed. Particularly, alkoxide and hydroxide induced nucleophilic trifluoromethylation of carbonyl compounds, disulfides and other electrophil...  
WO/2004/063149A1
Method for preparing methyl 2-diphenylmethylsulfinylacetate (MDMSA) comprising the steps of :(i) conversion of benzhydrol into methyldiphenylmethylthio-acetate ; and (ii) conversion of methyldiphenylmethylthioacetate into methyl-2-diphen...  
WO/2004/060885A1
A process for easily producing from an inexpensive material an optically active 2-thiomethyl-3-phenylpropionic acid derivative useful as an intermediate for medicines. An optically active 2-hydroxymethyl-3-phenylpropionic ester derivativ...  
WO/2004/043883A2
Carbon disulfide and hydrogen are reacted in the presence of a catalyst to form methyl mercaptans. The catalyst may be V2O5, Re2O7, or MnO supported on a substrate of CeO2, ZrO2, TiO2, Nb2O5, Al2O3, SiO2, Ta2O5, SnO2, or mixtures thereof...  
WO/2004/039772A1
The instant invetion provides a process for the preparation of S-(2-aminoethyl)-2-methyl-L-cysteine comprised of the steps of (i) esterification of 2-methyl-L-cystene; (ii) alkylation of the cysteine ester of step (i) to provide an N-pro...  
WO/2004/037774A1
Process for the Production of 3-methylthiopropanal. A process for the production of 3-methylthiopropanal which reacting reaction medium comprising methyl mercaptan and acrolein in the presence of a catalyst comprising an organic base cha...  
WO/2004/029005A1
The invention relates to a method of producing a mercaptan from an olefin and hydrogen sulphide. The inventive method is performed in the presence of hydrogen and a catalytic composition comprising a strong acid, such as a heteropolyacid...  
WO/2004/029022A2
The invention relates to a method of producing a mercaptan from a thioether and hydrogen sulphide. The inventive method is performed in the presence of hydrogen and a catalytic composition comprising a strong acid, such as a heteropolyac...  
WO/2004/024737A1
The invention relates to a method for binding heteroatom-carbon bonds. According to said method, a lithium compound (II) is first generated by reacting aliphatic or aromatic halogen compounds (I) with lithium metal, said compound is then...  
WO/2004/022766A1
A process for easily producing an L-&agr -methylcysteine derivative or its salt, which is useful as a drug intermediate, from a cheap easily procurable raw material through an enzymatic D-stereoselective hydrolysis of racemic 5-halomethy...  
WO/2004/016583A1
The compounds of formula (I) are substituted glycine derivatives useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropatho...  
WO/2004/016569A1
The present application relates to a new process for the reduction of sulfoxides to sulfides, wherein said process provides the production of a sulfide compound of formula (I), by the reduction of a sulfoxide compound of formula (II): wi...  
WO/2004/013094A2
One aspect of the present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-sulfur bond b...  
WO/2004/005245A1
A process for the preparation of compound (III) which comprises the reaction between a compound of general formula (V) and dicyano acetylene (IV), said reaction carried out in the presence of water (IV), (V), (III) wherein R is selected ...  
WO/2004/002951A2
The invention concerns a method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives, comprising: a) a step which consists in condensing a thiolate (that is a monoalkyl sulphide salt) with a compound having a sp3 hybrid...  
WO/2004/002939A2
The present invention relates to a compound formula [I]: Y is bond, -0-(CH2)n- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrog...  
WO/2004/000790A1
The present invention provides a compound of formula (I), wherein n is 0, 1 or 2 and R1 represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substituted by one o...  
WO/2003/106689A1
It is intended to provide a process for conveniently producing on an industrial scale an optically active &agr -methylcysteine derivative or its salt in the form of an L- or D-compound, which is useful as an intermediate of a drug, etc.,...  
WO/2003/104168A2
A process for reacting a first component with itself or a second component to produce a third component in which a first material comprising a first component or said first component and a second component is fed to divided wall column h...  
WO/2003/101944A1
A process for producing a compound of the general formula (IV) or a salt or solvate thereof, characterized in that a compound of the general formula (V) or a salt or solvate thereof is subjected to reaction for conversion to an alkylthio...  
WO/2003/099774A1
The present invention provides processes for the preparation of modafinil which includes the step of reacting benzhydrylthiol and chloroacetamide.  
WO/2003/099409A1
The invention concerns a method for producing specific crystalline modifications of an organic polymorphous substance. In accordance with said method, the specific crystalline modification is obtained by precipitation from a salt of the ...  
WO/2003/099777A1
The present invention relates to a novel process for the preparation of compounds of the formula (I) (I)by reacting in a first step amino alcohols of the formula (II) (II)with oleum to give sulphuric acid esters of the general formula (I...  

Matches 651 - 700 out of 5,486