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WO/2014/183555A1 |
The present invention relates to a cycloalkyl acid derivative, a preparation method thereof, and a pharmaceutical application thereof, and in particular, the present invention relates to a cycloalkyl acid derivative represented by genera...
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WO/2014/163156A1 |
The present invention provides a method for deprotecting a protected organic compound with high efficiency by catalytic hydrogenation. Specifically, the present invention provides a method characterized by deprotecting an organic compoun...
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WO/2014/153642A1 |
Novel imidazolium [1,2a] pyridine (ImPr) based protic ionic liquids with thiolate/disulfide and different carboxylate anions have been synthesized and characterized by NMR, IR and Mass spectroscopy. Thermogravimetry analysis (TGA) has be...
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WO/2014/154885A1 |
The invention relates to a catalyst comprising an active component based on molybdenum and on potassium and a support based on hydroxyapatite, and also to a process for preparing said catalyst and a process for producing methyl mercaptan...
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WO/2014/137741A1 |
The present inventions provides a method of treating a subject suffering from traumatic brain injury comprising administering to the subject an effective amount of an HDAC inhibitor, structurally represented, thereby treating the subject...
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WO/2014/137739A1 |
Compositions and methods are disclosed for repairing damaged keratin fibers or otherwise strengthening keratin fibers, including hair of the human scalp, and particularly hair that has been damaged chemically, physically, thermally or by...
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WO/2014/116792A1 |
Methods and intermediates useful for making compounds of Formula (I) are described, including a general method of making an alpha, beta-diamino ketone by reacting an imine with a 2-amino-substituted 1,3-dicarbonyl in a Mannich addition r...
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WO/2014/092133A1 |
Provided are: a separating agent and a platinum ion separation method that enable platinum ions to be separated from a solution containing low to high concentrations of platinum ions in a short time and with high selectivity; and a separ...
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WO/2014/084898A1 |
The present invention relates to synthetic organic antioxidants of small molecules. The novel dithiol-containing compounds in this invention possess strongest possible capability as both scavenger for free radicals and antioxidant. This ...
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WO/2014/078282A1 |
The present invention discloses polythiol compositions containing polythiol molecules having both thiol groups and intermolecular sulfide groups. Processes for producing such polythiol compositions also are described.
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WO/2014/071000A1 |
Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are prov...
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WO/2014/063983A1 |
The invention relates to new polysulfide mixtures containing compounds of formula (I), wherein n stands for 2 to 6 and R stands for C1-C8 alkyl, method for the production of said polysulfide mixtures, use of said polysulfide mixtures to ...
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WO/2014/066811A1 |
Degradable polymers were synthesized that self-assemble with nucleic acids, proteins, hydrophobic drugs, and other small molecules to form particles that are effective for delivery into a cell, tissue and/or organism either in vitro or i...
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WO/2014/061734A1 |
The present application addresses the problem of providing a novel salty taste-enhancing agent and a manufacturing method therefor, as well as a method for enhancing the salty taste of a food or drink. As a means for solving said problem...
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WO/2014/048958A1 |
The present invention relates to a method for the preparation of optionally substituted aryl and pyridyl pyrrolidines which are useful intermediates for the preparation of certain biologically active compounds.
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WO/2014/051057A1 |
The purpose of the present invention is to provide a gelling agent that enables an ionic liquid to be converted into a gel, even if the concentration of the ionic liquid is low, thereby providing an electrolyte gel having a low rate of d...
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WO/2014/045293A1 |
The disclosure herein provides a compound of formula 1, 2 and 3 or its pharmaceutical acceptable salts, as well as polymorphs, solvates, and hydrates thereof. These salts may be formulated as pharmaceutical compositions. The pharmaceutic...
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WO/2014/033967A1 |
A photo acid generator and/or a photo initiator consisting of sulfonium cation shown an formula (I) below and a tetra(fluorinated-aryl) borate anion; (In the formula (I), Ar1 is an hydrocarbon group comprising at least an aromatic group,...
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WO/2014/033399A1 |
The invention relates to a method for the production of symmetric or asymmetric dialkyl disulphides using at least one mixture of symmetric and/or asymmetric dialkyl disulphides in a photochemical and/or basic catalytic reaction, with th...
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WO/2014/027427A1 |
This production method for a polythiol compound comprises: a step in which 2-mercaptoethanol and an epihalohydrin compound represented by general formula (1) are reacted at a temperature of 10-50 °C in order to obtain a polyalcohol comp...
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WO/2014/027428A1 |
This production method for a polythiol compound comprises: a step in which the polyalcohol compound represented by formula (4) and thiourea are reacted in the presence of hydrogen chloride in order to obtain an isothiuronium salt; a step...
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WO/2014/027665A1 |
This polythiol composition contains: a polythiol compound (A) that has three or more mercapto groups; and a nitrogen-containing compound (B) that is obtained by substituting one mercapto group of the polythiol compound (A) with a group t...
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WO/2014/022879A1 |
The present invention relates to compounds for the treatment of mTOR (mammalian Target Of Rapamycin) pathway related diseases. Specifically, the present invention relates to the use of aminoactonitrile derivatives (AADs) in the treatment...
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WO/2013/185116A1 |
The description is directed to ionizable lipids useful for enhancing the delivery of therapeutic agents in liposomes.
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WO/2013/180271A1 |
Provided are a fluorine-containing amino acid prodrug represented by general formula (I) that makes a fluorine-containing amino acid which is a group 2 metabotropic glutamate receptor agonist into a prodrug, or a pharmacologically accept...
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WO/2013/176506A1 |
The present invention relates to a novel method for preparing a polythiol compound which is used for an optical material, and to a polymeric composition comprising the polythiol compound, and more particularly, to a composition and metho...
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WO/2013/175053A1 |
Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.
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WO/2013/168925A1 |
The present invention relates to a nanoparticle-based nitroaromatic explosive sensor for detecting nitroaromatic compounds, more specifically to stably detecting explosives in an aqueous solution by introducing, on the surface of the nan...
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WO/2013/157528A1 |
Provided is a medicinal agent comprising a compound represented by general formula (1), a pharmaceutically acceptable salt of the compound or a solvate of the compound or the pharmaceutically acceptable salt. A compound represented by ge...
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WO/2013/149019A1 |
A flavour composition comprising a compound of formula (I) and edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 t...
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WO/2013/134520A1 |
Novel tridentate-, bidentate-, and monodentate-based aromatic adsorbates including self-assembled monolayers (SAMs), especially, mixed multi-component SAMs, where the adsorbates comprise an aromatic ring including one head group or a plu...
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WO/2013/111999A1 |
The present invention relates to a polythiol compound for optical materials exhibiting desirable characteristics from a coloring perspective, a composition comprising same for optical materials, and a method for producing optical materia...
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WO/2013/112001A1 |
The present invention relates to a method for producing a polythiol compound used in thioepoxy-based optical materials and to a copolymer composition, comprising the polythiol compound, for thioepoxy-based optical materials, and particul...
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WO/2013/105688A1 |
The present invention relates to a novel method for preparing 1-(1'-(carboxymethyl)cyclopropane methyl disulfonyl methyl)cyclopropane acetic acid and derivatives thereof which are precursors of 1-(mercaptomethyl)cyclopropane acetic acid,...
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WO/2013/105873A1 |
The present invention relates to the use of soluble pentakis(alkylthio)derivatives of [60] fullerene as precursors for semiconducting thin [60] fullerene films by thermal decomposition and organic electronic devices using these films.
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WO/2013/098826A1 |
The present invention provides a process for the preparation of N-[2-[(acetylthio) methyl]-1-oxo-3-phenylpropyl] glycine phenyl methyl ester and intermediates thereof.
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WO/2013/097064A1 |
The present invention relates to an industrial method for producing diphenyl disulfide that may have a substituent, and to an industrially advantageous method for producing a high-purity disulfide with high yield and low environmental lo...
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WO/2013/098374A1 |
The present invention relates to novel 1,3-diphenylpropane derivatives, pharmaceutical compositions comprising the same and therapeutic uses thereof, in particular in the fields of human and animal health. The compounds according to the ...
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WO/2013/092129A1 |
The present invention relates to a catalyst which comprises a support material and an oxidic composition containing at least one alkali metal and tungsten, a process for producing such catalysts and also a process for preparing alkyl mer...
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WO/2013/082462A1 |
Provided herein is an amorphous form of a pharmaceutically acceptable salt of ezatiostat, for example, ezatiostat hydrochloride, compositions, uses and methods of preparation thereof.
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WO/2013/082299A1 |
Methods and therapeutic compositions are disclosed for treating neurodegenerative disorders and, in particular Amyotrophic Lateral Sclerosis, using sphingosine1-phosphate receptor modulators, such as fingolimod or a pharmaceutically acce...
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WO/2013/080049A2 |
The present invention provides efficient and economical methods for synthesis of (-)-2-exo-morpholinoisoborne-10-thiol, its enantiomer, and related chiral catalysts. Novel compounds and methods of asymmetric synthesis are also disclosed.
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WO/2013/076969A1 |
This method for producing a β-mercaptocarboxylic acid involves: a step (a) of obtaining a reaction solution including a compound represented by general formula (2) and a compound represented by general formula (3) by reacting a compound...
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WO/2013/055545A1 |
The present invention is directed towards a new class of semi-conducting acene derivatives. These compounds are soluble species and they all possess superior thermal stability and photooxidative resistance as compared to their counterpar...
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WO/2013/052943A2 |
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having sulfonamido-1-hydroxynaphthalene structure which function as inhibitors of Mcl-1 protein, and their use ...
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WO/2013/025999A2 |
Carbon dioxide capture and release includes contacting a gas comprising carbon dioxide with a mixture comprising a precursor and a solvent and reducing the precursor to form a capture agent. The capture agent is reacted with the carbon d...
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WO/2013/016839A1 |
Provided are photocurable compositions prepared from mercapto-benzophenone compounds as the key raw materials. The aim of the present invention is to solve the problems in the prior photocurable art that the small molecular photoinitiato...
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WO/2013/010102A2 |
The present invention provides compositions and methods for the administration and targeted delivery, release and/or formation of a drug compound from a halogenated phenol starting compound of the present invention at site(s) within the ...
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WO/2012/164118A1 |
The invention relates to compounds containing at least one polyphenol group and sulphur or selenium and to the uses thereof as antioxidants and free radical scavengers. In addition, the invention relates to pharmaceutical, nutraceutical ...
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WO/2012/155764A1 |
An α-diimine metal complex catalyst, wherein the metal may be nickel or palladium. The catalyst may be used for direct catalytic polymerization of olefins to provide the olefin polymer, further preparing the highly branched alkane mixtu...
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