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Matches 51 - 100 out of 717

Document Document Title
WO/2007/009798A2
A process of producing a compound of formula (3), wherein R1 is a C1-5alkyl group, R2 is a halogen atom, a C1-5 alkyl group, a C2-5 alkenyl group, a C2-5 alkynyl group, a C1-5 alkyl group, a C1-5 alkoxy group, a nitro group, or a hydroxy...  
WO/2006/029532A1
Nitrate esters and methods for mitigating neurodegeneration, affecting neuroprotection, affecting cognition enhancement, and/or preventing or mitigating tissue and/or cellular damage in a subject are described. Neurological or cognitive ...  
WO/2005/112915A2
The present invention provides compositions, methods, and kits for reducing oxidative stress thereby extending life span. The compositions, methods, and kits of the present invention can also be used to treat diseases of aging resulting ...  
WO/2005/068488A1
The invention relates to a solid phase synthesis method for synthesising compounds of general formula (I) on a resin, wherein Z is, in particular a hydrogen atom or a fluorogenic or chromogenic group, m and p are, in particular equal to ...  
WO/2005/060569A2
New bifunctional chelation complexes are described. These are based on the structure of the so-called 'TAME-HexA' molecule. The compounds are especially useful for forming chelation complexes with metal ions, including radioisotopes.  
WO/2005/057207A1
The present invention provides a method of forming an ion of formula (I) comprising the steps of: (i) reacting a compound of the formula (IIa); with a biopolymer, BP, having at least one group capable of reacting with M to form a covalen...  
WO/2005/054174A2
The invention relates to compounds for modulating the glycolysis enzyme complex and the transaminase complex, pharmaceutical compositions containing said compounds, and to the uses of said compounds for the production of pharmaceutical c...  
WO/2004/105929A2
A method and system for reactively destroying alkyl halides in volume or stream of gas. The method and device employ nucleophilic reaction of the alkyl halide under phase transfer catalysis conditions. The method and system are useful fo...  
WO/2004/089539A1
A catalyst composition comprising a support having a surface area of at least 500 m2/kg, and deposited on the support: - silver metal, - a metal or component comprising rhenium, tungsten, molybdenum or a nitrate- or nitrite-forming compo...  
WO/2004/039768A1
The invention relates to a method for producing phenyliso(thio)cyanates of general formula (I) according to which a compound of general formula (II) or the HCl adduct thereof is reacted with a phosgenating agent, wherein W represents oxy...  
WO/2004/031137A1
Compounds of formula (I) inhibit the processing of APP by gamma-secretase, and hence are useful in treatment of Alzheimer's disease.  
WO/2004/027388A2
The present invention provides novel fluorescent compounds and covalent attachment chemistries which facilitate the use of these compounds as labels for ultrasensitive and quantitative fluorescent detection of low levels of biomolecules....  
WO/2004/018414A2
The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein X=NH Y=CO, CS, -C(=N-CN) or X and Y together form an alkene, or C3-C5 cycloalkyl; R1 is -COOH; R2 is an electron withdrawing g...  
WO/2003/082946A1
Disclosed is a method for activating a composition comprising monomer units (TCM and/or SCM) which contain thiocyanate and/or selenocyanate, particularly vinylbenzyl thiocyanate and/or vinylbenzyl selenocyanate, according to which said c...  
WO/2003/074449A2
This invention provides androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpecte...  
WO/2003/074473A2
In one embodiment, this invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). The SARM compounds have unexpected a...  
WO/2003/070666A2
A method for preparing organic products from aqueous solutions, such as waste or byproduct liquid streams and waste or byproduct gas or vapor streams, uses phase transfer catalysis to transfer a chemical species in low concentration from...  
WO/2003/059896A1
The invention relates to a method for producing compounds of formula (I), wherein R represents H or F. Said method is characterised in that a compound of formula (II), wherein X represents halogen, mesylate or tosylate, is reacted with a...  
WO/2003/000647A1
The invention relates to a novel class of ligands, complexes comprising such ligands and a metal ion, and adducts of these metal complexes and a macromolecule. Pharmaceutical compositions and methods of making and using the ligand-metal ...  
WO/2002/076928A2
The invention relates to methods for preventing the attachment of aquatic organisms to surfaces that are submerged for extensive periods of time in water. More particularly, this invention relates to the protection of submerged surfaces ...  
WO/2002/057739A2
This invention relates to novel tracers and their synthesis and use in an immunoassay for the detection of controlled drugs such as amphetamine (APM), methamphetamine (MAPM) and their derivatives, in a biological or aqueous sample. In pa...  
WO/2002/020531A2
The invention relates to a method for producing anellated tetrahydro-[1H]-triazoles of formula I wherein the variables R?a¿, Z, Z?1¿, X, W, n and Q have the designations cited in patent claim 1, by cyclising compounds of general formul...  
WO/2002/004406A2
The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocyline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms...  
WO/2002/004411A1
Novel sulfate ester agents and the use of those agents for treating gastroesophageal reflux disease (GERD) are described, exemplary agents being of formula (I), wherein X is OCH¿2?- or CH¿2?O-; Y is a group pendant from X comprising at...  
WO/2001/070667A1
A compound represented by the formula (I) or a salt or solvate thereof; and a composition and a kit both containing any of these. In said formula X represents CH, sulfur, or nitrogen; Y represents CH, sulfur, or nitrogen or is absent; (a...  
WO/2001/068743A2
Disclosed are porous polymer/carrier solid phase reactants which consist of a polymer that consists of fine particles and is situated in the pore space of porous carrier materials. Reactive groups are bound to the polymer. Said groups ac...  
WO/2001/056962A1
Perfluoroisopropylbenzene derivatives of the general formula (I) or salts thereof, useful as intermediates or raw materials in the synthesis of various industrial materials including agricultural chemicals, drugs and surfactants, wherein...  
WO/2001/049275A2
Methods and therapeutic compounds for treating pain, mitigating inflammation, effecting analgesia and/or effecting sedation in a subject are described. A subject is administered an effective amount of a therapeutic compound which is a ni...  
WO/2001/044204A1
Disclosed are phenoxy and thiophenoxy acrylic acid compounds of general formula (I), wherein Z, V and W, independently from one another, mean oxygen or sulphur and Het stands for an unsaturated, five- or six-membered, heterocyclic radica...  
WO/2001/036400A1
The invention relates to a method for producing 2-chloro-5-chloromethyl-1,3-thiazol from compounds of formula (I), wherein X means Cl, -OR, -SR or NR¿2?, R being H or a suitable protective group; Y means H or Cl and Z means Cl or O, the...  
WO/2000/055117A1
The invention relates to new and known compounds as well as methods for preventing the attachment of aquatic organisms to surfaces which are submerged for extensive periods of time in water. More particularly, this invention relates to t...  
WO/2000/054756A2
Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effect...  
WO/2000/051976A1
The present invention provides a process for high yield regioselective synthesis of DTPA derivatives that eliminates the need for ion exchange chromatographic separation of intermediates. Moreover, as this process yields a single regiois...  
WO/2000/035860A2
The subject invention involves novel acyl isothiocyanate resins of formula (I) and processes for making them: (a) starting with a phenyl carboxy resin, treating the resin with any reagent that converts the carboxy to an acyl halide, foll...  
WO/2000/015625A2
The present invention relates to methods of making dihydropyrone HIV protease inhibitors.  
WO/2000/003975A2
The invention relates to aryl vinyl ether derivatives of general formula (I), wherein the substituents are as defined in the description; compositions containing them, processes and intermediates for their preparation and a method of con...  
WO/2000/002851A1
The present invention relates to compounds of formula (I), wherein A?1¿, A?2¿, R?1¿, R?2¿, R?3¿, X and n are as defined in the claims, which are valuable pharmaceutically active compounds for the therapy and prophylaxis of diseases,...  
WO/2000/001663A1
The present invention provides complexing agents of Formula (I) which contain novel photosensitizers and produce long-lived fluorescence for use in bioaffinity assays, especially HTRF (homogeneous time-resolved fluorescence) assays.  
WO/1999/043212A2
Biocidal preservatives for use especially in preventing rotting and deterioration of wood include quaternary ammonium compounds which preferably have a fatty aliphatic substituent on the quaternary nitrogen atom. Especially preferred are...  
WO/1998/053684A1
The invention relates to a fungicidal mixture characterized in that it contains in synergistically effective quantities a) a phenyl-benzylether derivative of the formula (I.a), (I.b) or (I.c), and/or a carbamate of the formula (Id), in w...  
WO/1998/025894A1
A process for the preparation of a thiocyanate of the Formula (II): R�f?-A�m?-(CH�2?)�n?-SCN wherein R�f? is a C�2?-C�20? perfluoroalkyl radical, or a C�5?-C�38? perfluoroalkyl radical having at least one ether oxygen a...  
WO/1998/016826A1
The subject invention provides a method of measuring very low levels of DBNPA. Novel DBNPA analogs are linked to a carrier protein and injected into an animal to provoke an immune response. The immune response is utilized to provide a hy...  
WO/1998/005659A1
Compounds of formula (3), and pharmaceutically acceptable salts and derivatives thereof, in which R?1� is vinyl or ethyl; and R?2� is a group R?3�, R?4�CH�2?-, or R?5�R?6�C=CH-; wherein each of R?3� and R?4� is an azabi...  
WO/1997/048684A1
This invention provides advantageous processes for preparing quinazolinones of Formula (I) wherein: R1 is C1-C10 alkyl; C3-C10 alkenyl; C3-C10 cycloalkyl; C3-C10 halocycloalkyl; C4-C10 cycloalkylalkyl; C4-C10 halocycloalkylalkyl; or C3-C...  
WO/1997/046540A1
The invention relates to novel sulphonyl amino(thio)carbonyl compounds of the formula (I) in which n is 0, 1 or 2, A is a single bond, oxygen, sulphur or the group N-R, where R is hydrogen, alkyl, alkenyl, alkinyl or cycloalkyl, Q is oxy...  
WO/1997/046521A1
Aliphatic nitrate esters having a sulfur or phosphorus atom 'beta' or 'gamma' to a nitrate group and their congeners having efficacy as neuroprotective agents are described. Preferred nitrate esters may be synthesized by nitration of a 3...  
WO/1997/043274A1
The present invention provides linker lipids for use in attaching a membrane including a plurality of ionophores to an electrode and providing a space between the membrane and the electrode. The membrane is either in part or totally made...  
WO/1997/034865A1
Compounds of formula (I), wherein R1, R2, R3, R4, R5 and G are as defined in the description and the dotted lines indicate an optional second bond, as well as the acid, base and ester addition salts thereof, a method for preparing said c...  
WO/1997/027203A1
Formation of an intramolecular cross-link in enzyme donor polypeptide fragments of 'beta'-galactosidase, thereby forming a cyclic enzyme donor which is hindered from complementation with an enzyme acceptor fragment to form active of 'bet...  
WO/1997/025309A1
Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful...  

Matches 51 - 100 out of 717